AB172570

Anti-HOXA13 antibody [EPR10357]

RabMAb
Recombinant
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(5 Publications)

Rabbit Recombinant Monoclonal HOXA13 antibody. Suitable for WB and reacts with Human samples. Cited in 5 publications.

View Alternative Names

HOX1J, HOXA13, Homeobox protein Hox-A13, Homeobox protein Hox-1J

1 Images

Supplier Data

Western blot - Anti-HOXA13 antibody [EPR10357] (AB172570)

All lanes:

Western blot - Anti-HOXA13 antibody [EPR10357] (ab172570) at 1/1000 dilution

Lane 1:

293T cell lysate at 10 µg

Lane 2:

K562 cell lysate at 10 µg

Lane 3:

Y79 cell lysate at 10 µg

Predicted band size: 39 kDa

true

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR10357

Isotype

IgG

Carrier free

Reacts with

Human

Applications

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "IHCP" : {"fullname" : "Immunohistochemistry paraffin embedded sections", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Mouse": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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Product details

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

pH: 7.2 - 7.4 Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.35% Sodium citrate, 0.17% Sodium chloride, 0.05% BSA, 0.03% EDTA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

HOXA13 also known as Homeobox protein Hox-A13 is a transcription factor belonging to the homeobox gene family. It plays an essential role in regulating gene expression during developmental processes. This protein weighs approximately 38 kDa. Researchers find HOXA13 expression in tissues of the limb and genitourinary tract during embryogenesis. It shows differential expression patterns which are significant in patterning these anatomical structures.

Biological function summary

Homeobox protein Hox-A13 influences limb and organ development. Its transcriptional regulation ensures proper tissue and organ formation by directing cellular differentiation. It forms a complex with other proteins necessary for executing specific genetic programs during development facilitating the fine-tuning of gene networks critical for morphogenesis of limbs and genitourinary systems.

Pathways

Homeobox protein Hox-A13 participates in the retinoic acid signaling pathway impacting cellular growth and differentiation. It also operates within the Wnt signaling pathway which is essential for developmental patterning. Through these pathways HOXA13 interacts with proteins such as HOXD13 and GLI3 which also participate in limb development and cellular differentiation processes creating a network that coordinates developmental signals.

Aberrant function of Homeobox protein Hox-A13 can lead to hand-foot-genital syndrome a condition involving limb and genitourinary tract malformations. Mutations or dysregulation in HOXA13 contribute to syndromes characterized by deformities in limb and organ structure. Additionally researchers link HOXA13 to the digenic inheritance of certain congenital malformations where it interacts with proteins like HOXD13 indicating its role in complex genetic disorders associated with developmental defects.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Sequence-specific, AT-rich binding transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.. Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

See full target information HOXA13

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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Hereditas 162:176 PubMed40877960

2025

HOXA13 promotes high glucose-induced trophoblast cell growth and migration during gestational diabetes by regulating the smad2 pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Fei Zhao,Xinhong Liu,Hong Qin

Computational and mathematical methods in medicine 2022:7214904 PubMed36276991

2022

Apatinib Functioned as Tumor Suppressor of Synovial Sarcoma through Regulating miR-34a-5p/HOXA13 Axis.

Applications

Unspecified application

Species

Unspecified reactive species

Qi Feng,Donglai Wang,Peng Guo,Zibo Zhang,Jiangang Feng

Cellular and molecular life sciences : CMLS 78:6505-6532 PubMed34420069

2021

A look into retinal organoids: methods, analytical techniques, and applications.

Applications

Unspecified application

Species

Unspecified reactive species

Tess A V Afanasyeva,Julio C Corral-Serrano,Alejandro Garanto,Ronald Roepman,Michael E Cheetham,Rob W J Collin

Free radical biology & medicine 168:25-43 PubMed33785413

2021

Targeting SLC3A2 subunit of system X is essential for mA reader YTHDC2 to be an endogenous ferroptosis inducer in lung adenocarcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Lifang Ma,Xiao Zhang,Keke Yu,Xin Xu,Tianxiang Chen,Yi Shi,Yikun Wang,Shiyu Qiu,Susu Guo,Jiangtao Cui,Yayou Miao,Xiaoting Tian,Lutao Du,Yongchun Yu,Jinjing Xia,Jiayi Wang

Frontiers in physiology 12:626248 PubMed33746773

2021

ETS Proto-Oncogene 1 Suppresses MicroRNA-128 Transcription to Promote Osteogenic Differentiation Through the HOXA13/β-Catenin Axis.

Applications

Unspecified application

Species

Unspecified reactive species

Renyao Li,Ying Dong,Feipeng Li

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-HOXA13 antibody [EPR10357]

Western blot - Anti-HOXA13 antibody [EPR10357] (AB172570)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Product details

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (5)

Complementary Products

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Product promise