Rabbit Recombinant Monoclonal HOXD10 antibody. Suitable for WB, Flow Cyt (Intra) and reacts with Human, Mouse samples. Cited in 10 publications.
IgG
Rabbit
pH: 7.2 - 7.4
Preservative: 0.01% Sodium azide
Constituents: 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 9% PBS, 0.05% BSA
Liquid
Monoclonal
IP | WB | IHC-P | ICC/IF | Flow Cyt (Intra) | |
---|---|---|---|---|---|
Human | Not recommended | Tested | Not recommended | Not recommended | Tested |
Mouse | Not recommended | Tested | Not recommended | Not recommended | Expected |
Rat | Not recommended | Predicted | Not recommended | Not recommended | Predicted |
Species | Dilution info | Notes |
---|---|---|
Species Mouse, Human, Rat | Dilution info - | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Human | Dilution info 1/1000 - 1/10000 | Notes - |
Species Mouse | Dilution info 1/1000 - 1/10000 | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Rat | Dilution info - | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Mouse, Human, Rat | Dilution info - | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Mouse, Human, Rat | Dilution info - | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Human | Dilution info 1/100 - 1/500 | Notes ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody. |
Species | Dilution info | Notes |
---|---|---|
Species Mouse | Dilution info Use at an assay dependent concentration. | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Rat | Dilution info - | Notes - |
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
HOX4D, HOX4E, HOX4E, HOX4D, HOXD10, Homeobox protein Hox-D10, Homeobox protein Hox-4D, Homeobox protein Hox-4E
Rabbit Recombinant Monoclonal HOXD10 antibody. Suitable for WB, Flow Cyt (Intra) and reacts with Human, Mouse samples. Cited in 10 publications.
IgG
Rabbit
pH: 7.2 - 7.4
Preservative: 0.01% Sodium azide
Constituents: 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 9% PBS, 0.05% BSA
Liquid
Monoclonal
EPR9374
Tissue culture supernatant
Blue Ice
+4°C
-20°C
Upon delivery aliquot
Avoid freeze / thaw cycle
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
This product is a recombinant monoclonal antibody, which offers several advantages including:
For more information, read more on recombinant antibodies.
This supplementary information is collated from multiple sources and compiled automatically.
The HOXD10 protein also known as Homeobox D10 is a member of the homeobox family of transcription factors that plays a mechanical role in regulating gene expression. This protein possesses a molecular mass of approximately 39 kDa. It primarily localizes in the nucleus where it binds to DNA and influences transcriptional activity during development and differentiation processes. HOXD10 expression occurs in tissues including the limbs and during various stages of embryonic development.
The HOXD10 protein contributes to limb morphology and development. It functions independently but also interacts with other proteins and factors to control morphogenetic processes. HOXD10 influences cellular differentiation by modulating the expression of target genes necessary for specifying position and structure in developing tissues. Its expression is tightly regulated to ensure proper developmental patterns including in limb formation and spatial organization.
The function of HOXD10 intricately links to the regulation of the developmental pathway known as the HOX gene pathway. This pathway coordinates with other pathways such as those controlling limb development to ensure the correct timing and positioning of structures during embryogenesis. Within these pathways other homeobox proteins like HOXA10 and HOXD11 have similar roles complementing and sometimes interacting with HOXD10 to orchestrate the precise patterning necessary for normal development.
Mutations or dysregulation of HOXD10 associate with limb malformations and possibly contribute to the development of some cancers like breast carcinoma. Its aberrant expression influences the activity of other critical proteins involved in cellular proliferation and differentiation such as p53 which affects tumorigenesis. Understanding the role and regulation of HOXD10 could provide insights into novel therapeutic strategies for these conditions.
We have tested this species and application combination and it works. It is covered by our product promise.
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
We do not recommend this combination. It is not covered by our product promise.
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In the unlikely event of one of our products not working as expected, you are covered by our product promise.
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Terms & Conditions.
All lanes: Western blot - Anti-HOXD10 antibody [EPR9374] (ab138508) at 1/1000 dilution
Lane 1: ECV-304 cell lysate at 10 µg
Lane 2: Fetal heart cell lysate at 10 µg
Lane 3: Mouse heart cell lysate at 10 µg
Lane 4: HeLa cell lysate at 10 µg
All lanes: HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 38 kDa
Intracellular flow cytometrical analysis of permeabilized HeLa cells with ab138508 antibody at a dilution of 1/100 (red) or a rabbit IgG negative (green).
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