Rabbit Recombinant Monoclonal VL1 antibody. Suitable for IHC-P and reacts with Human papillomavirus samples. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human papillomavirus type 16 Major capsid protein L1.
Images
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HPV16 L1 antibody [HPV16/2058R] (AB234305), expandable thumbnail](https://content.abcam.com/products/images/hpv16-l1-antibody-hpv16-2058r-ab234305--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img114804.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HPV16 L1 antibody [HPV16/2058R] (AB234305)")
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2 - 7.4
Preservative: 0.05% Sodium azide
Constituents: PBS, 0.05% BSA- Form
- Liquid
- Clonality
- Monoclonal
Immunogen
- Recombinant Full Length Protein corresponding to Human papillomavirus type 16 Major capsid protein L1. Database link P03101
Reactivity data
Select an application| IHC-P | |
|---|---|
| Human papillomavirus | Tested |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human papillomavirus | Dilution info 0.5-1 µg/mL | Notes Incubate with primary antibody for 30 minutes at room temperature. Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Associated Products
Select an associated product type
2 products for Alternative Product
Target data
Function
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2.
Additional Targets
HPV16 L1
Alternative names
Major capsid protein L1, L1
Recommended products
Rabbit Recombinant Monoclonal VL1 antibody. Suitable for IHC-P and reacts with Human papillomavirus samples. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human papillomavirus type 16 Major capsid protein L1.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2 - 7.4
Preservative: 0.05% Sodium azide
Constituents: PBS, 0.05% BSA- Form
- Liquid
- Clonality
- Monoclonal
- Immunogen
- Recombinant Full Length Protein corresponding to Human papillomavirus type 16 Major capsid protein L1. Database link P03101
- Clone number
- HPV16/2058R
- Purification technique
- Affinity purification Protein A/G
- Concentration
- Purification notes
Purified from bioreactor concentrate by Protein A/G.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HPV16 L1 antibody [HPV16/2058R] (ab234305), expandable thumbnail](https://content.abcam.com/products/images/hpv16-l1-antibody-hpv16-2058r-ab234305--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img114804.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HPV16 L1 antibody [HPV16/2058R] (ab234305)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HPV16 L1 antibody [HPV16/2058R] (ab234305)
Formalin-fixed, paraffin-embedded human cervix tissue stained for HPV16 L1 using ab234305 at 1 μg/ml in immunohistochemical analysis.
Downloads
Product protocols
- Visit the general protocols
- Visit troubleshooting
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