Goat Polyclonal alpha Lactalbumin antibody - conjugated to HRP. Suitable for ICC, ELISA, WB, IHC-P and reacts with Cow samples.
pH: 6.8 - 7.4
Preservative: 0.05% CMIT/MIT based preservative
Constituents: 0.2% BSA
| ICC | ELISA | WB | IHC-P | |
|---|---|---|---|---|
| Cow | Expected | Expected | Expected | Expected |
| Species | Dilution info | Notes |
|---|---|---|
Species Cow | Dilution info Use at an assay dependent concentration. | Notes - |
| Species | Dilution info | Notes |
|---|---|---|
Species Cow | Dilution info Use at an assay dependent concentration. | Notes - |
| Species | Dilution info | Notes |
|---|---|---|
Species Cow | Dilution info - | Notes Colorimetric: Use 1/1000-1/10000 dilution; Chemiluminescent: Use 1/1000-1/30000 dilution. |
| Species | Dilution info | Notes |
|---|---|---|
Species Cow | Dilution info Use at an assay dependent concentration. | Notes - |
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Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.
ALACTA, LALBA, Alpha-lactalbumin, Lactose synthase B protein
Goat Polyclonal alpha Lactalbumin antibody - conjugated to HRP. Suitable for ICC, ELISA, WB, IHC-P and reacts with Cow samples.
pH: 6.8 - 7.4
Preservative: 0.05% CMIT/MIT based preservative
Constituents: 0.2% BSA
Antiserum was solid phase adsorbed to ensure specificity. ab112973 was isolated by affinity chromatography using antigen coupled to agarose beads.
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Alpha-lactalbumin commonly known as lactalbumin or alpha-lactoglobulin has a mass of approximately 14.2 kDa. This protein is mainly expressed in the mammary glands of mammals where it serves an important function in lactose synthesis. It modifies the action of galactosyltransferase an enzyme to enable the transfer of sugar units resulting in the production of lactose. The biochemical role of this lactalbumin protein including its unique structure is important in adapting the lactation system to meet the nutritional needs of offspring.
Alpha-lactalbumin's role is closely linked to the synthesis and secretion of milk. It functions as part of the lactose synthase complex which is essential for converting glucose to lactose. This conversion is important because lactose dictates milk osmotic pressure affecting milk volume and overall composition. In addition to its primary role in milk production this protein structure supports various cellular processes due to its ability to bind calcium and other ions.
Alpha-lactalbumin participates mainly in the lactose synthesis pathway. In this metabolic map it interacts extensively with other proteins involved in milk production particularly beta-14-galactosyltransferase. This interaction enhances the efficiency of lactose production. Its presence in these pathways epitomizes the close relationship and cellular coordination needed for effective lactose synthesis during lactation.
Researchers have identified connections between alpha-lactalbumin and breast cancer as well as lactose intolerance. Changes in the expression levels of this protein can impact the development and regulation of tumors in breast tissue linked to interactions with proteins such as casein. Furthermore variants of alpha-lactalbumin can affect individuals with lactose intolerance where the protein's role in regulating lactose production must be managed to alleviate symptoms.
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This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
We do not recommend this combination. It is not covered by our product promise.
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