AB305591

HRP Anti-Histone H3 (mutated K36M) antibody [EPR23614-91]

RabMAb
Recombinant
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Rabbit Recombinant Monoclonal H3 mutated K36M antibody - conjugated to HRP.

View Alternative Names

H3.3A, H3F3, H3F3A, PP781, H3-3B, H3.3B, H3F3B, H3-3A, Histone H3.3, H3K36M, H3.3K36M, H3K36

665 Alexa Fluor® 647

Alexa Fluor® 647 Anti-Histone H3 (mutated K36M) antibody [EPR23614-91]
578 PE

PE Anti-Histone H3 (mutated K36M) antibody [EPR23614-91]
660 APC

APC Anti-Histone H3 (mutated K36M) antibody [EPR23614-91]
519 Alexa Fluor® 488

Alexa Fluor® 488 Anti-Histone H3 (mutated K36M) antibody [EPR23614-91]
617 Alexa Fluor® 594

Alexa Fluor® 594 Anti-Histone H3 (mutated K36M) antibody [EPR23614-91]
565 Alexa Fluor® 555

Alexa Fluor® 555 Anti-Histone H3 (mutated K36M) antibody [EPR23614-91]
603 Alexa Fluor® 568

Alexa Fluor® 568 Anti-Histone H3 (mutated K36M) antibody [EPR23614-91]
775 Alexa Fluor® 750

Alexa Fluor® 750 Anti-Histone H3 (mutated K36M) antibody [EPR23614-91]
Unconjugated

Anti-Histone H3 (mutated K36M) antibody [EPR23614-91]
Carrier free

Anti-Histone H3 (mutated K36M) antibody [EPR23614-91] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR23614-91

Isotype

IgG

Conjugation

HRP

Excitation/Emission

Carrier free

Applications

Antibody Labelling, Target Binding Affinity

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Product details

This conjugated primary antibody is "made to order" and it is released using a quantitative quality control method that ensures binding affinity and labelling efficiency of the conjugate. Via leveraging the power of the Lightning-Link^® conjugation technology, Abcam will deliver highly consistent recombinant conjugates in <2 weeks, giving you access to an ever growing portfolio of antibody-label combinations.

For suitable applications and species reactivity, please refer to the unconjugated version of this clone.

How are conjugated primary antibodies validated?
This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling.
For suitable applications and species reactivity, please refer to the unconjugated version of this clone.

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

pH: 7.4 Preservative: 0.1% Proclin 300 Solution Constituents: PBS, 30% Glycerol (glycerin, glycerine), 1% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle|Store in the dark

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

See full target information H3-3A mutated K36M

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

HRP Anti-Histone H3 (mutated K36M) antibody [EPR23614-91]

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Key facts

Host species

Clonality

Clone number

Isotype

Conjugation

Excitation/Emission

Carrier free

Applications

Immunogen

Product details

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

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Product promise