AB106492

HRP Anti-IL-11 antibody [KT62]

Name: HRP Anti-IL-11 antibody [KT62] (ab106492) | Abcam
Brand: Abcam Limited
SKU: AB106492

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(1 Publication)

Mouse Monoclonal IL-11 antibody - conjugated to HRP. Suitable for sELISA and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human IL11.

View Alternative Names

Interleukin-11, IL-11, Adipogenesis inhibitory factor, AGIF, IL11, IL 11, Interleukin 11

1 Images

Sandwich ELISA - HRP Anti-IL-11 antibody [KT62] (AB106492)

sELISA

Unknown

Sandwich ELISA - HRP Anti-IL-11 antibody [KT62] (AB106492)

ab106492 at 1/1000 dilution detecting IL-11 by sandwich ELISA. The capture antibody is an mouse monoclonal (IgG1) raised against Human IL-11.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

KT62

Isotype

IgG1

Conjugation

HRP

Excitation/Emission

Carrier free

Reacts with

Human

Applications

sELISA

applications

Immunogen

Recombinant Full Length Protein corresponding to Human IL11.

P20809

Specificity

ab106492 is specific for Human Interleukin 11

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "sELISA-species-checked": "testedAndGuaranteed", "sELISA-species-dilution-info": "1/1000", "sELISA-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

+4°C

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed : 2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and IL11RA activates a signaling cascade that promotes cell proliferation (PubMed : 12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. The interaction with the membrane-bound IL11RA and IL6ST stimulates 'classic signaling', whereas the binding of IL11 and soluble IL11RA to IL6ST stimulates 'trans-signaling' (PubMed : 30279168).

See full target information IL11

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Oncotarget 6:26651-62 PubMed26450852

2015

Liver X receptor ligand cytotoxicity in colon cancer cells and not in normal colon epithelial cells depends on LXRβ subcellular localization.

Applications

Unspecified application

Species

Unspecified reactive species

Flavie Courtaut,Valentin Derangère,Angélique Chevriaux,Sylvain Ladoire,Alexia K Cotte,Laurent Arnould,Romain Boidot,Mickaël Rialland,François Ghiringhelli,Cédric Rébé

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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HRP Anti-IL-11 antibody [KT62]

Sandwich ELISA - HRP Anti-IL-11 antibody [KT62] (AB106492)

Key facts

Host species

Clonality

Clone number

Isotype

Conjugation

Excitation/Emission

Carrier free

Reacts with

Applications

Immunogen

Specificity

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Product protocols

Target data

Publications (1)

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