Mouse Monoclonal IL-11 antibody - conjugated to HRP. Suitable for sELISA and reacts with Human samples. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human Interleukin-11.
Images
![Sandwich ELISA - HRP Anti-IL-11 antibody [KT62] (AB106492), expandable thumbnail](https://content.abcam.com/products/images/hrp-il-11-antibody-kt62-ab106492--sandwich-elisa-img26782.jpg/_jcr_content/renditions/webp-475.webp "Sandwich ELISA - HRP Anti-IL-11 antibody [KT62] (AB106492)")
Key facts
- Isotype
- IgG1
- Host species
- Mouse
- Conjugation
- HRP
- Storage buffer
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: PBS- Form
- Liquid
- Clonality
- Monoclonal
Immunogen
- Recombinant Full Length Protein corresponding to Human Interleukin-11. Database link P20809
Reactivity data
Select an application| sELISA | |
|---|---|
| Human | Tested |
sELISA
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/1000 | Notes - |
Associated Products
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Target data
Function
Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and IL11RA activates a signaling cascade that promotes cell proliferation (PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. The interaction with the membrane-bound IL11RA and IL6ST stimulates 'classic signaling', whereas the binding of IL11 and soluble IL11RA to IL6ST stimulates 'trans-signaling' (PubMed:30279168).
Alternative names
Interleukin-11, IL-11, Adipogenesis inhibitory factor, AGIF, IL11
Recommended products
Mouse Monoclonal IL-11 antibody - conjugated to HRP. Suitable for sELISA and reacts with Human samples. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human Interleukin-11.
Key facts
- Isotype
- IgG1
- Host species
- Mouse
- Conjugation
- HRP
- Storage buffer
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: PBS- Form
- Liquid
- Clonality
- Monoclonal
- Immunogen
- Recombinant Full Length Protein corresponding to Human Interleukin-11. Database link P20809
- Clone number
- KT62
- Purification technique
- Affinity purification Protein A
- Specificity
ab106492 is specific for Human Interleukin 11
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- +4°C
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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1 product image
![Sandwich ELISA - HRP Anti-IL-11 antibody [KT62] (ab106492), expandable thumbnail](https://content.abcam.com/products/images/hrp-il-11-antibody-kt62-ab106492--sandwich-elisa-img26782.jpg "Sandwich ELISA - HRP Anti-IL-11 antibody [KT62] (ab106492)")
Sandwich ELISA - HRP Anti-IL-11 antibody [KT62] (ab106492)
ab106492 at 1/1000 dilution detecting IL-11 by sandwich ELISA. The capture antibody is an mouse monoclonal (IgG1) raised against Human IL-11.
Downloads
Product protocols
- Visit the general protocols
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