Goat Polyclonal M1 antibody - conjugated to HRP. Suitable for ELISA, WB, ICC/IF and reacts with Influenza A samples. Cited in 1 publication.
Preservative: 0.002% Thimerosal (merthiolate)
Constituents: PBS, 1% BSA
| IHC | ELISA | WB | ICC/IF | |
|---|---|---|---|---|
| Influenza A | Not recommended | Expected | Expected | Expected |
| Species | Dilution info | Notes |
|---|---|---|
Species Influenza A | Dilution info - | Notes - |
| Species | Dilution info | Notes |
|---|---|---|
Species Influenza A | Dilution info Use at an assay dependent concentration. | Notes - |
| Species | Dilution info | Notes |
|---|---|---|
Species Influenza A | Dilution info Use at an assay dependent concentration. | Notes - |
| Species | Dilution info | Notes |
|---|---|---|
Species Influenza A | Dilution info Use at an assay dependent concentration. | Notes - |
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Plays critical roles in virus replication, from virus entry and uncoating to assembly and budding of the virus particle. M1 binding to ribonucleocapsids (RNPs) in nucleus seems to inhibit viral transcription. Interaction of viral NEP with M1-RNP is thought to promote nuclear export of the complex, which is targeted to the virion assembly site at the apical plasma membrane in polarized epithelial cells. Interactions with NA and HA may bring M1, a non-raft-associated protein, into lipid rafts. Forms a continuous shell on the inner side of the lipid bilayer in virion, where it binds the RNP. During virus entry into cell, the M2 ion channel acidifies the internal virion core, inducing M1 dissociation from the RNP. M1-free RNPs are transported to the nucleus, where viral transcription and replication can take place. Determines the virion's shape: spherical or filamentous. Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology. Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
Matrix protein 1, M1, M
Goat Polyclonal M1 antibody - conjugated to HRP. Suitable for ELISA, WB, ICC/IF and reacts with Influenza A samples. Cited in 1 publication.
Preservative: 0.002% Thimerosal (merthiolate)
Constituents: PBS, 1% BSA
Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.
The antibody is covalently coupled to a highly purified preparation of horseradish peroxidase (RZ>3). Care is taken to ensure adequate conjugation while preserving maximum enzyme activity. Free enzyme is removed.
We have tested this species and application combination and it works. It is covered by our product promise.
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
We do not recommend this combination. It is not covered by our product promise.
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