Goat Polyclonal Respiratory Syncytial Virus antibody - conjugated to HRP. Suitable for ELISA, IHC-P, Neut and reacts with Respiratory syncytial virus samples. Cited in 3 publications. Immunogen corresponding to Virus preparation containing Respiratory Syncytial Virus protein.
Preservative: 0.002% Thimerosal (merthiolate)
Constituents: PBS, 1% BSA
ELISA | IHC-P | Neut | |
---|---|---|---|
Respiratory syncytial virus | Expected | Expected | Expected |
Species | Dilution info | Notes |
---|---|---|
Species Respiratory syncytial virus | Dilution info Use at an assay dependent concentration. | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Respiratory syncytial virus | Dilution info Use at an assay dependent concentration. | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Respiratory syncytial virus | Dilution info Use at an assay dependent concentration. | Notes - |
Select an associated product type
RS virus, RSV
Goat Polyclonal Respiratory Syncytial Virus antibody - conjugated to HRP. Suitable for ELISA, IHC-P, Neut and reacts with Respiratory syncytial virus samples. Cited in 3 publications. Immunogen corresponding to Virus preparation containing Respiratory Syncytial Virus protein.
Preservative: 0.002% Thimerosal (merthiolate)
Constituents: PBS, 1% BSA
Covalently coupled to a highly purified preparation of Horseradish Peroxidase (RZ>3). Care is taken to ensure adequate conjugation while preserving maximum enzyme activity. Free enzyme is removed.
Respiratory Syncytial Virus (RSV) is a negative-sense single-stranded RNA virus known to cause respiratory infections. It belongs to the Paramyxoviridae family and is sometimes referred to by its alternate names like Human Orthopneumovirus. RSV is approximately 15 kb in size. It is predominantly expressed in the respiratory tract where it attacks epithelial cells leading to infection. The virus's ability to form a syncytium a large multinucleate cell is one of its mechanical strategies to aid in the spread across the host cells.
The virus propagates efficiently within the host tissue leading to serious respiratory illness in infants and young children. RSV is not part of a specific complex but it engages host cellular machinery to promote its replication and prevent immune detection. The fusion (F) protein of RSV plays a critical role in mediating membrane fusion facilitating viral entry into the host cells. The involvement of viral proteins in modulating host immune responses is significant for the virus's life cycle.
Respiratory infections caused by RSV connect to the host's immune signaling pathways including the toll-like receptor (TLR) pathways and the interferon response pathway. The interaction of RSV proteins with these pathways leads to an increased inflammatory response. Proteins such as the RSV G protein interface with the chemokine receptor pathway which helps in modulation of the immune system to allow viral persistence. These interactions demonstrate the virus's strategies to evade immune surveillance and promote infection.
Respiratory syncytial virus is a major cause of bronchiolitis and pneumonia in infants and young children. The virus's activity in the respiratory tract contributes to severe inflammation and cell damage which can lead to hospitalization. Other proteins like RSV M protein are involved in virus assembly and budding and they passively influence disease progression by impacting viral load and the host's immune response. Understanding these interactions is important for developing therapeutic strategies including anti-RSV monoclonal antibodies like palivizumab (2F7) which target prominent viral components to prevent severe disease outcomes.
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This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
We do not recommend this combination. It is not covered by our product promise.
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