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AB238900

Anti-HSD17B7 antibody

5

(1 Review)

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(1 Publication)

Rabbit Polyclonal HSD17B7 antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human HSD17B7 aa 100-200.

View Alternative Names

17HSD7, SDR37C1, UNQ2563/PRO6243, HSD17B7, 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7, 17-beta-hydroxysteroid dehydrogenase 7, 3-keto-steroid reductase, Dihydrotestosterone oxidoreductase, Estradiol 17-beta-dehydrogenase 7, Short chain dehydrogenase/reductase family 37C member 1, 17-beta-HSD 7

2 Images
Immunocytochemistry/ Immunofluorescence - Anti-HSD17B7 antibody (AB238900)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-HSD17B7 antibody (AB238900)

MCF7 (Human breast adenocarcinoma cell line) cells stained for HSD17B7 (green) using ab238900 at 1/100 dilution in ICC/IF. Secondary antibody is an Alexa-Fluor® 488-conjugated Goat Anti-Rabbit IgG (H+L).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HSD17B7 antibody (AB238900)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HSD17B7 antibody (AB238900)

Paraffin-embedded human adrenal gland tissue stained for HSD17B7 using ab238900 at 1/100 dilution in immunohistochemical analysis.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human HSD17B7 aa 100-200. The exact immunogen used to generate this antibody is proprietary information.

P56937

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Primary Antibodies

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SRD5A1 antibody (AB110123)

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Primary Antibodies

AB124785

Anti-LSS antibody [EPR6704(B)]

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-LSS antibody [EPR6704(B)] (AB124785)

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Sample Prep & Detection Kits

AB64261

Rabbit specific HRP/DAB Detection IHC Kit

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Rabbit specific HRP/DAB Detection IHC Kit (AB64261)

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Primary Antibodies

AB65156

Anti-HSD3B1 antibody

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/50 - 1/200", "ICCIF-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Purification notes
Purity greater than 95%.
Storage buffer
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Bifunctional enzyme involved in steroid-hormone metabolism and cholesterol biosynthesis (PubMed : 11165030, PubMed : 12574203, PubMed : 12732193, PubMed : 12829805, PubMed : 19772289, PubMed : 20659585). Catalyzes the NADP(H)-dependent reduction of estrogens and androgens and regulates the biological potency of these steroids. Converts estrone (E1) to a more potent estrogen, 17beta-estradiol (E2) (PubMed : 12574203, PubMed : 12732193, PubMed : 19772289). Converts dihydrotestosterone (DHT) to its inactive form 5a-androstane-3b,17b-diol (PubMed : 12574203, PubMed : 12732193, PubMed : 19772289). Converts moderately progesterone to 3beta-hydroxypregn-4-ene-20-one, leading to its inactivation (PubMed : 12574203, PubMed : 12732193). Additionally, participates in the post-squalene cholesterol biosynthesis, as a 3-ketosteroid reductase (PubMed : 11165030, PubMed : 12829805, PubMed : 20659585).. Isoform 3. Does not have enzymatic activities toward E1 and DHT.
See full target information HSD17B7
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

International journal of biological sciences 20:1045-1063 PubMed38322121

2024

The homeoprotein HOXB2 limits triple-negative breast carcinogenesis via extracellular matrix remodeling.

Applications

Unspecified application

Species

Unspecified reactive species

Ji Hoon Oh,Clara Yuri Kim,Da Som Jeong,Yu Cheon Kim,Myoung Hee Kim,Je-Yoel Cho
View all publications
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Product promise

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For full details, please see our Terms & Conditions

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