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AB6511

Anti-HSV1 gG Envelope Protein antibody [7F5]

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(3 Publications)

Mouse Monoclonal GG antibody. Suitable for ICC/IF, WB, ELISA and reacts with Herpes simplex virus samples. Cited in 3 publications.

View Alternative Names

Glycoprotein G, HHV1 gG envelope protein, Herpes simplex virus 1 glycoprotein G, US4

1 Images
Western blot - Anti-HSV1 gG Envelope Protein antibody [7F5] (AB6511)
  • WB

Unknown

Western blot - Anti-HSV1 gG Envelope Protein antibody [7F5] (AB6511)

Western blot with ab6511.
Lane 1 : ab6511 at 1 : 10,000
Lane 2 : ab6511 at 1 : 20,000
Lane 3 : ab6511 at 1 : 40,000
Lane 4 : ab6511 at 1 : 80,000

All lanes:

Western blot - Anti-HSV1 gG Envelope Protein antibody [7F5] (ab6511)

Predicted band size: 25 kDa

false

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

7F5

Isotype

IgG2a

Light chain type

kappa

Carrier free

No

Reacts with

Herpes simplex virus

Applications

ELISA, ICC/IF, WB

applications

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Herpes simplex virus": { "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "1/25600", "ICCIF-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/80000", "WB-species-notes": "<p></p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "1/102400", "ELISA-species-notes": "<p></p>" } } }

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.4
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The HSV1 gG envelope protein also known as glycoprotein G is an important part of the Herpes Simplex Virus 1. This protein has a molecular mass of approximately 71 kDa. It is a type I membrane protein found in the viral envelope and on the surface of infected host cells. Glycoprotein G plays a role in viral attachment and entry into the host cells helping the virus infect and propagate within the host organism.
Biological function summary

Glycoprotein G assists in the immune evasion by binding to host immune modulators reducing immune detection. Glycoprotein G is part of the larger complex involved in viral infection along with other glycoproteins such as gB gD and gH. These components work together to facilitate the fusion of the viral and host cell membranes which allows viral entry into the host cell.

Pathways

Glycoprotein G participates in the viral entry pathway and immune modulation pathways. In the viral entry pathway it interacts with other viral glycoproteins like gD which binds to host cell receptors like nectin-1. This interaction is important for the viral fusion process. The immune modulation pathway involves interference with host immune responses where glycoprotein G assists in decreasing the recognition by host antibodies.

Glycoprotein G expression relates to Herpes Simplex Virus type 1 (HSV-1) infections and complications such as herpes labialis and encephalitis. These infections can result in recurrent lesions around the oral or facial area and severe complications in neural tissues. Glycoprotein G has connections to other viral proteins like glycoprotein B and D through its role in initiating viral infections contributing to disease progression and symptom manifestations.

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Molecular therapy : the journal of the American Society of Gene Therapy 33:703-722 PubMed39674886

2024

Single-cell data-driven design of armed oncolytic virus to boost cooperative innate-adaptive immunity against cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Jiliang Zhao,Han Wang,Chunlei Wang,Fan Li,Jingru Chen,Feilong Zhou,Yiping Zhu,Jinhua Chen,Jinming Liu,Hao Zheng,Nanxin Gong,Yazhuo Du,Yufan Zhang,Li Deng,Yuyao Du,Yanqin Liu,Yuanke Li,Na Li,Hongru Zhang,Dan Ding,Shouzhi Yu,Cuizhu Zhang,Yingbin Yan,Wei Wang,Youjia Cao,Yuntao Zhang,Hongkai Zhang

mBio 15:e0330823 PubMed38275838

2024

Herpes simplex virus type 1 modifies the protein composition of extracellular vesicles to promote neurite outgrowth and neuroinfection.

Applications

Unspecified application

Species

Unspecified reactive species

Guorong Sun,Kai Alexander Kropp,Marieluise Kirchner,Nina Plückebaum,Anton Selich,Manutea Serrero,Akshay Dhingra,Jorge Rubén Cabrera,Birgit Ritter,Rudolf Bauerfeind,Emanuel Wyler,Markus Landthaler,Axel Schambach,Beate Sodeik,Philipp Mertins,Abel Viejo-Borbolla

Cell death and differentiation 23:197-206 PubMed26068589

2015

The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress.

Applications

Unspecified application

Species

Unspecified reactive species

M Petroni,F Sardina,C Heil,M Sahún-Roncero,V Colicchia,V Veschi,S Albini,D Fruci,B Ricci,A Soriani,L Di Marcotullio,I Screpanti,A Gulino,G Giannini
View all publications

Product promise

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