JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB34568

Anti-HSV1 + HSV2 antibody

Be the first to review this product! Submit a review

|

(0 Publication)

Goat Polyclonal HSV1 antibody. Suitable for ELISA, ICC/IF and reacts with Herpes simplex virus, Human herpesvirus 2 samples. Immunogen corresponding to Virus preparation containing Human alphaherpesvirus 1 strain F protein.

View Alternative Names

Herpes simplex virus, Herpes simplex virus 1, Herpes simplex virus type 1, Human Herpesvirus 1, Human herpesvirus type 1

Key facts

Host species

Goat

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Herpes simplex virus, Human herpesvirus 2

Applications

ICC/IF, ELISA

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

Specificity

ab34568 recognises ICP's and late structural (virion) antigens. It does not recognise HepG2 cells.

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Herpes simplex virus": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" }, "Human herpesvirus 2": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" } } }
style
left-column
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification notes
ab34568 is a purified IgG. Its purity state is >95%.
Storage buffer
pH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

HSV1 and HSV2 short for Herpes Simplex Virus Type 1 and Type 2 are double-stranded DNA viruses with similar structure and function. They are encapsulated with a lipid envelope featuring glycoproteins which are important for viral entry into host cells. These viruses have a capsid housing the viral genome and weigh around 150 kDa. HSV1 and HSV2 are primarily expressed in epithelial tissues and the nervous system specifically in neurons where they establish latency. HSV1 and HSV2 antibodies as well as anti-HSV1 antibodies and anti-HSV2 antibodies target these viruses aiding in research and diagnostics.
Biological function summary

HSV1 and HSV2 have significant roles in viral infection processes. They form complexes with host cell receptors to facilitate adhesion and entry into cells. Their glycoproteins interact with cellular proteins to trigger fusion and facilitate viral replication. During this process the viruses actively modulate the host's immune response enabling the evasion of immune detection. The ability to remain dormant and reactivate is an important aspect of their biology.

Pathways

HSV1 and HSV2 participate in cell entry and immune evasion processes. These viruses exploit the host's cellular machinery via the MAPK signaling pathway and the PI3K/Akt pathway to enhance viral replication and survival. The viral proteins ICP0 and glycoprotein D are essential for modulating these pathways. These interactions impact the immune response and cellular cycle regulation allowing the virus to maintain its presence within the host.

HSV1 and HSV2 are significant contributors to conditions like oral herpes and genital herpes. They are also associated with severe infections such as Herpes Simplex Encephalitis. The HSV1 and HSV2 target proteins through their interaction with host proteins facilitate these infections. Herpes Simplex Virus type-specific antibodies help in detecting and studying these viruses leading to better understanding and treatment of related conditions.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

See full target information HSV1

Additional targets

HSV2
style
left-column
style
left-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions
style
left-column
style
right-column

Associated Products

Select an associated product type
Alternative Product
Primary Antibodies

AB20922

HRP Anti-HSV1 + HSV2 antibody

primary-antibodies

hrp-hsv1-hsv2-antibody-ab20922

0

(0 reviews)

Alternative Product
Primary Antibodies

AB226858

Anti-HSV1 + HSV2 antibody

primary-antibodies

hsv1-hsv2-antibody-ab226858

0

(0 reviews)

style
bg-slate-100

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com