Mouse Monoclonal ICAM1 antibody. Suitable for WB and reacts with Human samples. Cited in 26 publications. Immunogen corresponding to Cell preparation containing ICAM1 protein.
Images
![Western blot - Anti-ICAM1 antibody [15.2] (AB20), expandable thumbnail](https://content.abcam.com/products/images/icam1-antibody-152-ab20--western-blot-img53146.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-ICAM1 antibody [15.2] (AB20)")
Publications
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- Frontiers in cell and developmental biology 8:152020Agrin Influences Botulinum Neurotoxin A-Induced Nerve Sprouting via miR-144-agrin-MuSK Signaling.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLin Ma,Lizhen Pan,Wuchao Liu,Ying Liu,Xuerui Xiang,Yougui Pan,Xiaolong Zhang,Lingjing JinPubMed 32083076
- Nature communications 10:56882019Involvement of condensin in cellular senescence through gene regulation and compartmental reorganization.Applications:Unspecified applicationReactive species:Unspecified reactive speciesOsamu Iwasaki,Hideki Tanizawa,Kyoung-Dong Kim,Andrew Kossenkov,Timothy Nacarelli,Sanki Tashiro,Sonali Majumdar,Louise C Showe,Rugang Zhang,Ken-Ichi NomaPubMed 31831736
- Medical science monitor : international medical jo 25:6946-69542019The Effects of the CXCR4 Antagonist, AMD3465, on Human Retinal Vascular Endothelial Cells (hRVECs) in a High Glucose Model of Diabetic Retinopathy.Applications:Unspecified applicationReactive species:Unspecified reactive speciesDi Wu et. al.PubMed 31860633
- PPAR research 2019:27151762019Peroxisome Proliferator-Activated Receptor-γ Antagonizes LOX-1-Mediated Endothelial Injury by Transcriptional Activation of miR-590-5p.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLei Xu et. al.PubMed 31354796
- mBio 10:2019Binding Heterogeneity of Plasmodium falciparum to Engineered 3D Brain Microvessels Is Mediated by EPCR and ICAM-1.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMaria Bernabeu et. al.PubMed 31138740
- International journal of molecular sciences 20:2018Protective Effects of Total Saponins of (Miq.) on Endothelial Cell Injury Induced by TNF-α via Modulation of the PI3K/Akt and NF-κB Signalling Pathways.Applications:Unspecified applicationReactive species:Unspecified reactive speciesPing Zhou et. al.PubMed 30577658
- Journal of colloid and interface science 538:630-6372018Intercellular adhesion molecule 1 antibody-mediated mesoporous drug delivery system for targeted treatment of triple-negative breast cancer.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMengru Wang et. al.PubMed 30554096
- Frontiers in immunology 9:3312018Tissue Damage Caused by Myeloablative, but Not Non-Myeloablative, Conditioning before Allogeneic Stem Cell Transplantation Results in Dermal Macrophage Recruitment without Active T-Cell Interaction.Applications:Unspecified applicationReactive species:Unspecified reactive speciesPeter van Balen et. al.PubMed 29535719
- Molecular medicine reports 17:3877-38832018Puerarin protects endothelial progenitor cells from damage of angiotensin II via activation of ERK1/2‑Nrf2 signaling pathway.Applications:Unspecified applicationReactive species:Unspecified reactive speciesChen Fu,Baoxin Chen,Xianglan Jin,Xuemei Liu,Fengli Wang,Rongjuan Guo,Zhigang Chen,Hong Zheng,Le Wang,Yunling ZhangPubMed 29359784
- Molecular medicine reports 16:8635-86422017Calcium dobesilate may alleviate diabetes‑induced endothelial dysfunction and inflammation.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYijun Zhou et. al.PubMed 29039485
Key facts
- Isotype
- IgG1
- Host species
- Mouse
- Storage buffer
pH: 7.2
Preservative: 0.09% Sodium azide
Constituents: 0.87% Sodium chloride, 0.14% Sodium dihydrogen phosphate- Form
- Liquid
- Clonality
- Monoclonal
Immunogen
- Cell preparation containing ICAM1 protein. The exact immunogen used to generate this antibody is proprietary information. Database link P05362
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Reactivity data
Select an application| WB | IHC-P | |
|---|---|---|
| Human | Tested | Not recommended |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info - | Notes - |
IHC-P
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info - | Notes - |
Associated Products
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Target data
Function
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. (Microbial infection) Acts as a receptor for major receptor group rhinovirus A-B capsid proteins. (Microbial infection) Acts as a receptor for Coxsackievirus A21 capsid proteins. (Microbial infection) Upon Kaposi's sarcoma-associated herpesvirus/HHV-8 infection, is degraded by viral E3 ubiquitin ligase MIR2, presumably to prevent lysis of infected cells by cytotoxic T-lymphocytes and NK cell.
Alternative names
CD54, Intercellular adhesion molecule 1, ICAM-1, Major group rhinovirus receptor, ICAM1
Recommended products
Mouse Monoclonal ICAM1 antibody. Suitable for WB and reacts with Human samples. Cited in 26 publications. Immunogen corresponding to Cell preparation containing ICAM1 protein.
Key facts
- Isotype
- IgG1
- Host species
- Mouse
- Storage buffer
pH: 7.2
Preservative: 0.09% Sodium azide
Constituents: 0.87% Sodium chloride, 0.14% Sodium dihydrogen phosphate- Form
- Liquid
- Clonality
- Monoclonal
- Immunogen
- Cell preparation containing ICAM1 protein. The exact immunogen used to generate this antibody is proprietary information. Database link P05362
- Clone number
- 15.2
- Purification technique
- Affinity purification
- Concentration
- Purification notes
This purified format is guaranteed to be >90% pure as determined by SDS-PAGE analysis.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- +4°C
- Storage information
- Do Not Freeze, Store undiluted
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
![Western blot - Anti-ICAM1 antibody [15.2] (ab20), expandable thumbnail](https://content.abcam.com/products/images/icam1-antibody-152-ab20--western-blot-img53146.jpg "Western blot - Anti-ICAM1 antibody [15.2] (ab20)")
Western blot - Anti-ICAM1 antibody [15.2] (ab20)
All lanes: Western blot - Anti-ICAM1 antibody [15.2] (ab20) at 5 µg/mL
Lane 1: SK N BE (Human neuroblastoma) whole cell lysate at 10 µg
Lane 2: Saos-2 (Human epithelial-like osteosarcoma cell line) whole cell lysate at 10 µg
Lane 3: HT1080 (Human fibrosarcoma) whole cell lysate at 10 µg
SecondaryAll lanes: Goat polyclonal to Mouse IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
Predicted band size: 57 kDa
Observed band size: 58 kDa
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