Rabbit Polyclonal IGF2 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 4 publications.
Images
Publications
Filter by
- Medicine 102:e328622023Urinary insulin signaling pathway related proteins may serve as potential biomarkers for monitoring diabetes mellitus without hypertension and hyperlipidemia.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMan Zhao,Qian Meng,Man ZhangPubMed 36749274
- Journal of clinical and translational hepatology 11:787-7992023IGF2-NR4A2 Signaling Regulates Macrophage Subtypes to Attenuate Liver Cirrhosis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLichao Yao,Xue Hu,Mengqin Yuan,Qiuling Zhang,Pingji Liu,Lian Yang,Kai Dai,Yingan JiangPubMed 37408817
- Nature communications 13:20832022Astroblastomas exhibit radial glia stem cell lineages and differential expression of imprinted and X-inactivation escape genes.Applications:Unspecified applicationReactive species:Unspecified reactive speciesNorman L Lehman,Nathalie Spassky,Müge Sak,Amy Webb,Cory T Zumbar,Aisulu Usubalieva,Khaled J Alkhateeb,Joseph P McElroy,Kirsteen H Maclean,Paolo Fadda,Tom Liu,Vineela Gangalapudi,Jamie Carver,Zied Abdullaev,Cynthia Timmers,John R Parker,Christopher R Pierson,Bret C Mobley,Murat Gokden,Eyas M Hattab,Timothy Parrett,Ralph X Cooke,Trang D Lehman,Stefan Costinean,Anil Parwani,Brian J Williams,Randy L Jensen,Kenneth Aldape,Akshitkumar M MistryPubMed 35440587
- Cell reports 32:1080072020Runx2+ Niche Cells Maintain Incisor Mesenchymal Tissue Homeostasis through IGF Signaling.Applications:Unspecified applicationReactive species:Unspecified reactive speciesShuo Chen,Junjun Jing,Yuan Yuan,Jifan Feng,Xia Han,Quan Wen,Thach-Vu Ho,Chelsea Lee,Yang ChaiPubMed 32783935
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine)- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
Reactivity data
Select an application| WB | IHC-P | |
|---|---|---|
| Human | Tested | Expected |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/500 - 1/3000 | Notes - |
IHC-P
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/100 - 1/1000 | Notes - |
Associated Products
Select an associated product type
3 products for Alternative Product
Target data
Function
The insulin-like growth factors possess growth-promoting activity (By similarity). Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF2 is influenced by placental lactogen. Also involved in tissue differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver (Probable). Acts as a ligand for integrin which is required for IGF2 signaling (PubMed:28873464). Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation (By similarity). Inhibits myoblast differentiation and modulates metabolism via increasing the mitochondrial respiration rate (By similarity). Preptin undergoes glucose-mediated co-secretion with insulin, and acts as a physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
Alternative names
IGF-2, PP1446, IGF2, Insulin-like growth factor 2, Insulin-like growth factor II, Somatomedin-A, T3M-11-derived growth factor, IGF-II
Recommended products
Rabbit Polyclonal IGF2 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 4 publications.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine)- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
- Purification technique
- Affinity purification Immunogen
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
2 product images
Western blot - Anti-IGF2 antibody (ab262713)
12% SDS-PAGE
All lanes: Western blot - Anti-IGF2 antibody (ab262713) at 1/1000 dilution
Lane 1: HepG2 whole cell extract at 30 µg
Lane 2: HepG2 conditioned medium at 30 µg
Predicted band size: 20 kDa
Western blot - Anti-IGF2 antibody (ab262713)
15% SDS-PAGE
All lanes: Western blot - Anti-IGF2 antibody (ab262713) at 1/1000 dilution
Lane 1: Non-transfected HEK-293T whole cell extract/lysate at 30 µg
Lane 2: IGF2-transfected HEK-293T whole cell extract/lysate at 30 µg
Predicted band size: 20 kDa
Downloads
Product protocols
- Visit the general protocols
- Visit troubleshooting
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com