AB86461

Anti-IGFBP3 antibody [RM0096-11B16]

(1 Review)

(1 Publication)

Rat Monoclonal IGFBP3 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Mouse Igfbp3.

View Alternative Names

Igfbp-3, Igfbp3, Insulin-like growth factor-binding protein 3, IBP-3, IGF-binding protein 3, IGFBP-3

1 Images

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Western blot - Anti-IGFBP3 antibody [RM0096-11B16] (AB86461)

All lanes:

Western blot - Anti-IGFBP3 antibody [RM0096-11B16] (ab86461)

All lanes:

Lysates of human placenta tissue

Predicted band size: 32 kDa

Observed band size: 40 kDa

false

Key facts

Host species

Rat

Clonality

Monoclonal

Clone number

RM0096-11B16

Isotype

IgG2

Carrier free

Reacts with

Human

Applications

applications

Immunogen

Recombinant Full Length Protein corresponding to Mouse Igfbp3.

P47878

Specificity

No cross reactivity seen to other IGFBP proteins.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>" } } }

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Product details

ab86461 was produced from a hybridoma (mouse myeloma fused with spleen cells from an immunized rat).

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Purification notes

IgG fraction of culture supernatant purified by Protein A/G affinity chromatography and 0.2 µm filtered.

Storage buffer

Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. Promotes testicular germ cell apoptosis.

See full target information Igfbp3

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in molecular neuroscience 10:431 PubMed29311819

2017

Neuronal ICAM-5 Inhibits Microglia Adhesion and Phagocytosis and Promotes an Anti-inflammatory Response in LPS Stimulated Microglia.

Applications

Unspecified application

Species

Unspecified reactive species

Sonja Paetau,Taisia Rolova,Lin Ning,Carl G Gahmberg

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-IGFBP3 antibody [RM0096-11B16]

Western blot - Anti-IGFBP3 antibody [RM0096-11B16] (AB86461)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

Specificity

Alternative Products

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Primary Antibodies

Secondary Antibodies

Reactivity data

Product details

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (1)

Product promise