AB109765

Anti-IGFBP6 antibody

Name: Anti-IGFBP6 antibody (ab109765) | Abcam
Brand: Abcam Limited
SKU: AB109765
Price: 630 USD
Availability: InStock

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(4 Publications)

Goat Polyclonal IGFBP6 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Synthetic Peptide within Human IGFBP6 aa 100-150.

View Alternative Names

IBP6, IGFBP6, Insulin-like growth factor-binding protein 6, IBP-6, IGF-binding protein 6, IGFBP-6

2 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IGFBP6 antibody (AB109765)

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IGFBP6 antibody (AB109765)

ab109765 at 5μg/ml staining IGFBP6 in Human Skeletal Muscle, Formalin-Fixed, Paraffin-Embedded.

Unknown

Western blot - Anti-IGFBP6 antibody (AB109765)

Primary incubation was 1 hour

All lanes:

Western blot - Anti-IGFBP6 antibody (ab109765) at 0.5 µg/mL

All lanes:

Human Adrenal Gland lysate at 35 µg

Predicted band size: 25 kDa

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Key facts

Host species

Goat

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

WB, IHC-P

applications

Immunogen

Synthetic Peptide within Human IGFBP6 aa 100-150. The exact immunogen used to generate this antibody is proprietary information.

P24592

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-1.5 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5 µg/mL", "IHCP-species-notes": "<p></p>" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Pig": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Sheep": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.3 Preservative: 0.02% Sodium azide Constituents: Tris buffered saline, 0.5% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Activates the MAPK signaling pathway and induces cell migration (PubMed : 24003225).

See full target information IGFBP6

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Publications (4)

Recent publications for all applications. Explore the full list and refine your search

Animal bioscience 35:544-555 PubMed34530511

2021

Alterations of mRNA and lncRNA profiles associated with the extracellular matrix and spermatogenesis in goats.

Applications

Unspecified application

Species

Unspecified reactive species

Haolin Chen,Xiaomeng Miao,Jinge Xu,Ling Pu,Liang Li,Yong Han,Fengxian Mao,Youji Ma

Frontiers in genetics 12:662843 PubMed34149804

2021

Effect of the Expression of and Genes on the Metastatic Potential of Breast Cancer Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Sergey Nikulin,Galina Zakharova,Andrey Poloznikov,Maria Raigorodskaya,Daniel Wicklein,Udo Schumacher,Stepan Nersisyan,Jonas Bergquist,Georgy Bakalkin,Lidiia Astakhova,Alexander Tonevitsky

Molecular & cellular proteomics : MCP 18:818-836 PubMed30705123

2019

Integration of Two In-depth Quantitative Proteomics Approaches Determines the Kallikrein-related Peptidase 7 (KLK7) Degradome in Ovarian Cancer Cell Secretome.

Applications

Unspecified application

Species

Unspecified reactive species

Lakmali Munasinghage Silva,Thomas Kryza,Thomas Stoll,Christine Hoogland,Ying Dong,Carson Ryan Stephens,Marcus Lachlan Hastie,Viktor Magdolen,Oded Kleifeld,Jeffrey John Gorman,Judith Ann Clements

Oncology letters 13:4161-4168 PubMed28588703

2017

Decreased expression of insulin-like growth factor binding protein 6 is associated with gastric adenocarcinoma prognosis.

Applications

Unspecified application

Species

Unspecified reactive species

Changqing Zeng,Xingyu Feng,Wei Wang,Lin Lv,Cheng Fang,Liangjie Chi,Liangxiang Huang,Zhiwei Zhou

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-IGFBP6 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IGFBP6 antibody (AB109765)

Western blot - Anti-IGFBP6 antibody (AB109765)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (4)

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