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AB63510

Anti-IKB beta (phospho T19) antibody

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(1 Publication)

Rabbit Polyclonal IKB beta phospho T19 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human NFKBIB phospho T19.

View Alternative Names

IKBB, TRIP9, NFKBIB, NF-kappa-B inhibitor beta, NF-kappa-BIB, I-kappa-B-beta, Thyroid receptor-interacting protein 9, IkB-B, IkB-beta, IkappaBbeta, TR-interacting protein 9, TRIP-9

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Synthetic Peptide within Human NFKBIB phospho T19. The exact immunogen used to generate this antibody is proprietary information.

Q15653

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AB32518

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>" } } }
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Product details

Detects IkB beta only when phosphorylated at threonine 19.
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Purification notes
The antibody against non-phosphopeptide was removed by chromatographyusing non-phosphopeptide corresponding to the phosphorylation site
Storage buffer
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Storage information
Stable for 12 months at -20°C
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
See full target information NFKBIB phospho T19
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 14:5063 PubMed37604828

2023

Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen.

Applications

Unspecified application

Species

Unspecified reactive species

Katharine M Wright,Sarah R DiNapoli,Michelle S Miller,P Aitana Azurmendi,Xiaowei Zhao,Zhiheng Yu,Mayukh Chakrabarti,WuXian Shi,Jacqueline Douglass,Michael S Hwang,Emily Han-Chung Hsiue,Brian J Mog,Alexander H Pearlman,Suman Paul,Maximilian F Konig,Drew M Pardoll,Chetan Bettegowda,Nickolas Papadopoulos,Kenneth W Kinzler,Bert Vogelstein,Shibin Zhou,Sandra B Gabelli
View all publications
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Product promise

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