JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB239584

Anti-IL-1 alpha antibody [C5]

Be the first to review this product! Submit a review

|

(2 Publications)

Mouse Monoclonal IL-1 alpha antibody. Suitable for WB and reacts with Rat, Goat samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Goat IL1A aa 50 to C-terminus.

View Alternative Names

Interleukin-1 alpha, IL-1 alpha, Il1a

4 Images
Western blot - Anti-IL-1 alpha antibody [C5] (AB239584)
  • WB

Supplier Data

Western blot - Anti-IL-1 alpha antibody [C5] (AB239584)

All lanes:

Western blot - Anti-IL-1 alpha antibody [C5] (ab239584) at 3 µg/mL

All lanes:

Rat lung lysate

Predicted band size: 31 kDa

false

Western blot - Anti-IL-1 alpha antibody [C5] (AB239584)
  • WB

Supplier Data

Western blot - Anti-IL-1 alpha antibody [C5] (AB239584)

All lanes:

Western blot - Anti-IL-1 alpha antibody [C5] (ab239584) at 3 µg/mL

All lanes:

Goat liver lysate

Predicted band size: 31 kDa

false

Western blot - Anti-IL-1 alpha antibody [C5] (AB239584)
  • WB

Supplier Data

Western blot - Anti-IL-1 alpha antibody [C5] (AB239584)

All lanes:

Western blot - Anti-IL-1 alpha antibody [C5] (ab239584) at 3 µg/mL

All lanes:

Goat lung lysate

Predicted band size: 31 kDa

false

Western blot - Anti-IL-1 alpha antibody [C5] (AB239584)
  • WB

Supplier Data

Western blot - Anti-IL-1 alpha antibody [C5] (AB239584)

All lanes:

Western blot - Anti-IL-1 alpha antibody [C5] (ab239584) at 3 µg/mL

All lanes:

Rat liver lysate

Predicted band size: 31 kDa

false

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

C5

Isotype

IgG

Carrier free

No

Reacts with

Rat, Goat

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Goat IL1A aa 50 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

P79161

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-5 µg/mL", "WB-species-notes": "<p></p>" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Goat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-5 µg/mL", "WB-species-notes": "<p></p>" }, "Sheep": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A/G
Purification notes
Purified from TCS.
Storage buffer
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Cytokine constitutively present intracellularly in nearly all resting non-hematopoietic cells that plays an important role in inflammation and bridges the innate and adaptive immune systems. After binding to its receptor IL1R1 together with its accessory protein IL1RAP, forms the high affinity interleukin-1 receptor complex. Signaling involves the recruitment of adapter molecules such as MYD88, IRAK1 or IRAK4. In turn, mediates the activation of NF-kappa-B and the three MAPK pathways p38, p42/p44 and JNK pathways. Within the cell, acts as an alarmin and cell death results in its liberation in the extracellular space after disruption of the cell membrane to induce inflammation and alert the host to injury or damage. In addition to its role as a danger signal, which occurs when the cytokine is passively released by cell necrosis, directly senses DNA damage and acts as signal for genotoxic stress without loss of cell integrity.
See full target information Il1a

Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in pharmacology 16:1567942 PubMed40535769

2025

Pomolic acid induces ferroptosis-mediated cell death in non-small cell lung cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Wenbin Ji,Yanbin Zhang,Wenhao Ji,Hui Zhang,Biao Qin,Xiao-Liang Xing,Zaiqi Zhang

Pharmaceutical biology 60:2229-2236 PubMed36367996

2022

Ginsenoside Rb1 reduces oxidative/carbonyl stress damage and ameliorates inflammation in the lung of streptozotocin-induced diabetic rats.

Applications

Unspecified application

Species

Unspecified reactive species

Hao Su,Cheng-Ju Tian,Ying Wang,Jiaojiao Shi,Xiaoxiao Chen,Zhong Zhen,Yu Bai,Lan Deng,Chunpeng Feng,Zhuang Ma,Jinfeng Liu
View all publications

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com