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AB18955

Anti-IL-1 beta antibody

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(2 Publications)

Rabbit Polyclonal IL-1 beta antibody. Suitable for WB, FuncS (Neut/Block) and reacts with Recombinant full length protein - Mouse, Mouse samples. Cited in 2 publications.

View Alternative Names

Interleukin-1 beta, IL-1 beta, Il1b

1 Images
Western blot - Anti-IL-1 beta antibody (AB18955)
  • WB

Supplier Data

Western blot - Anti-IL-1 beta antibody (AB18955)

All lanes:

Western blot - Anti-IL-1 beta antibody (ab18955) at 4 µg/mL

Lane 1:

Recombinant Murine IL-1β at 0.01 µg

Lane 2:

Recombinant Murine IL-1β at 0.05 µg

Lane 3:

Recombinant Murine IL-1β at 0.25 µg

Predicted band size: 30 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse

Applications

FuncS (Neut/Block), WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Primary Antibodies

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "FuncSNeutBlock" : {"fullname" : "Functional Studies (Neut/Block)", "shortname":"FuncS (Neut/Block)"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "FuncSNeutBlock-species-checked": "guaranteed", "FuncSNeutBlock-species-dilution-info": "", "FuncSNeutBlock-species-notes": "<p></p>" }, "Recombinant full length protein - Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>", "FuncSNeutBlock-species-checked": "notRecommended", "FuncSNeutBlock-species-dilution-info": "", "FuncSNeutBlock-species-notes": "" } } }
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Product details

This product is manufactured by BioVision, an Abcam company and was previously called 5129 Anti-Murine IL-1β Polyclonal Antibody. 5129-100 is the same size as the 100 µg size of ab18955.

The antibody solution should be gently mixed before use.

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Properties and storage information

Form
Liquid
Storage buffer
pH: 7.2 Preservative: 0.03% Proclin 300 Constituents: PBS, 30% Glycerol (glycerin, glycerine), 0.5% BSA, 0.1% EDTA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis : its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
See full target information Il1b
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in microbiology 15:1518150 PubMed39850131

2025

Exploring the alleviating effects of metabolite lactic acid on non-alcoholic steatohepatitis through the gut-liver axis.

Applications

Unspecified application

Species

Unspecified reactive species

Hongmei Zhao,Juan Zhou,Lingzhi Yuan,Zhiyi Sun,Yi Liu,Xinyu Zhao,Feng Ye

Frontiers in pharmacology 15:1366479 PubMed38595921

2024

Inhibition of ACOX1 enhances the therapeutic efficacy of obeticholic acid in treating non-alcoholic fatty liver disease and mitigates its lipotoxicity.

Applications

Unspecified application

Species

Unspecified reactive species

Yuping Yang,Weinan Yuan,Kun He,Chuangzhen Lin,Shenshen Du,Yanqi Kou,Biao Nie
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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