AB9787

Anti-IL-1 beta antibody

Name: Anti-IL-1 beta antibody (ab9787) | Abcam
Brand: Abcam Limited
SKU: AB9787
Price: 400 USD
Availability: InStock
Rating: 3 (3 reviews)

Lab Essentials
What is this?

(3 Reviews)

(99 Publications)

Rabbit Polyclonal IL-1 beta antibody. Suitable for sELISA and reacts with Recombinant full length protein - Rat samples. Cited in 99 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Rat Il1b.

View Alternative Names

Interleukin-1 beta, IL-1 beta, Il1b

1 Images

Sandwich ELISA - Anti-IL-1 beta antibody (AB9787)

sELISA

Supplier Data

Sandwich ELISA - Anti-IL-1 beta antibody (AB9787)

This antigen affinity purified antibody, in conjunction with a suitable detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant Rat IL-1 beta.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Light chain type

unknown

Carrier free

Applications

sELISA

applications

Immunogen

Recombinant Full Length Protein corresponding to Rat Il1b.

Q63264

Specificity

This antibody is used in our Rat IL-1beta EDK and was tested against the following rat growth factors at 50ng/ml to determine if there was any cross reactivity: GM-CSF, IL1alpha, IL-2, IL-4, IL-10, SCF, & TNFalpha. No significant cross reactivity was detected. The antibody has not been tested against endogenous IL1beta, only recombinant protein and we cannot guarantee it will detect endogenous protein.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Recombinant full length protein - Rat": { "sELISA-species-checked": "testedAndGuaranteed", "sELISA-species-dilution-info": "0.5-2 µg/mL", "sELISA-species-notes": "<p>To detect Rat IL-1 beta by sandwich ELISA (using 100 μl/well antibody solution) a concentration of 0.5 - 2.0 μg/ml of ab9787 is required. This antigen affinity purified antibody, in conjunction with a ab245863 detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant Rat IL-1 beta.</p>" } } }

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Product details

This product is no longer batch tested in IHC, for an IHC validated antibody please see ab156791

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Properties and storage information

Form

Lyophilized

Reconstitution

reconstitute with water at 200µL

Purification technique

Affinity purification Immunogen

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis : its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.

See full target information Il1b

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Publications (99)

Recent publications for all applications. Explore the full list and refine your search

Naunyn-Schmiedeberg's archives of pharmacology : PubMed41006906

2025

Combined dapagliflozin and pioglitazone therapy in diabetic nephropathy: no added benefit beyond monotherapy in inflammation and fibrosis.

Applications

Unspecified application

Species

Unspecified reactive species

Cinakova A,Vavrincova-Yaghi D,Vavrinec P,Krenek P,Klimas J,Kralova E

Iranian journal of basic medical sciences 28:1004-1011 PubMed40584448

2025

Inhibition of HDAC3 induces neuroprotection by activating the Npas4 signaling pathway following surgical brain injury in rats.

Applications

Unspecified application

Species

Unspecified reactive species

Haiping Gu,Yating Gong,Muyao Wu,Mengying Shi,Jiejie Yu,Hongfei Zhu,Ya-Ming Sun,Baoqi Dang

Arthritis research & therapy 27:47 PubMed40038756

2025

Does extracorporeal shockwave therapy treat leg length discrepancy? an experimental animal study.

Applications

Unspecified application

Species

Unspecified reactive species

Shun-Wun Jhan,Kuan-Ting Wu,Wen-Yi Chou,Jeng-Wei Chen,Ka-Kit Siu,Wen-Chiung Huang,Ching-Jen Wang,Jai-Hong Cheng

Molecular medicine (Cambridge, Mass.) 30:173 PubMed39390372

2024

Drp1 acetylation mediated by CDK5-AMPK-GCN5L1 axis promotes cerebral ischemic injury via facilitating mitochondrial fission.

Applications

Unspecified application

Species

Unspecified reactive species

Jiejie Zhang,Shan Wang,Haitao Zhang,Xiaotong Yang,Xin Ren,Lei Wang,Yihan Yang,Yi Yang,Ya Wen

Aging 16:3404-3419 PubMed38349868

2024

Orexin-A alleviates ferroptosis by activating the Nrf2/HO-1 signaling pathway in traumatic brain injury.

Applications

Unspecified application

Species

Unspecified reactive species

Junwei Kang,Bingkai Ren,Lianghua Huang,Xiaoyang Dong,Qi Xiong,Zhen Feng

The Tohoku journal of experimental medicine 262:245-252 PubMed38267059

2024

Reduction of Edema and Pain in Transcutaneous Electrical Nerve Stimulation Treated-Arthritic Rat.

Applications

Unspecified application

Species

Unspecified reactive species

Hye Rim Suh,Hwi-Young Cho

Molecular neurobiology 61:1580-1592 PubMed37731080

2023

Description of Novel Molecular Factors in Lumbar DRGs and Spinal Cord Factors Underlying Development of Neuropathic Pain Component in the Animal Model of Osteoarthritis.

Applications

Unspecified application

Species

Unspecified reactive species

Natalia Malek,Jakub Mlost,Magdalena Kostrzewa,Jolanta Rajca,Katarzyna Starowicz

BMC cardiovascular disorders 23:410 PubMed37596540

2023

Allicin protects against LPS-induced cardiomyocyte injury by activating Nrf2-HO-1 and inhibiting NLRP3 pathways.

Applications

Unspecified application

Species

Unspecified reactive species

Fangyuan Sun,Kailiang Xu,Jiayi Zhou,Wei Zhang,Guihe Duan,Ming Lei

Brain, behavior, and immunity 110:125-139 PubMed36863493

2023

Chronic ethanol induces a pro-inflammatory switch in interleukin-1β regulation of GABAergic signaling in the medial prefrontal cortex of male mice.

Applications

Unspecified application

Species

Unspecified reactive species

F P Varodayan,A R Pahng,T D Davis,P Gandhi,M Bajo,M Q Steinman,W B Kiosses,Y A Blednov,M D Burkart,S Edwards,A J Roberts,M Roberto

International journal of oral science 15:10 PubMed36797252

2023

PPAR-γ activation promotes xenogenic bioroot regeneration by attenuating the xenograft induced-oxidative stress.

Applications

Unspecified application

Species

Unspecified reactive species

Tingting Lan,Fei Bi,Yuchan Xu,Xiaoli Yin,Jie Chen,Xue Han,Weihua Guo

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-IL-1 beta antibody

Sandwich ELISA - Anti-IL-1 beta antibody (AB9787)

Key facts

Host species

Clonality

Isotype

Light chain type

Carrier free

Applications

Immunogen

Specificity

Reactivity data

Product details

Properties and storage information

Form

Reconstitution

Purification technique

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Product protocols

Target data

Publications (99)

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