AB89887

Anti-IL-11 antibody [MM0361-9T27]

Name: Anti-IL-11 antibody [MM0361-9T27] (ab89887) | Abcam
Brand: Abcam Limited
SKU: AB89887

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(2 Publications)

Mouse Monoclonal IL-11 antibody. Suitable for WB, FuncS (Neut/Block) and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human IL11.

View Alternative Names

Interleukin-11, IL-11, Adipogenesis inhibitory factor, AGIF, IL11, IL 11, Interleukin 11

1 Images

Supplier Data

Western blot - Anti-IL-11 antibody [MM0361-9T27] (AB89887)

All lanes:

Western blot - Anti-IL-11 antibody [MM0361-9T27] (ab89887) at 1/500 dilution

All lanes:

Human placenta tissue lysate

Predicted band size: 21 kDa

false

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

MM0361-9T27

Isotype

IgG2

Carrier free

Reacts with

Human

Applications

FuncS (Neut/Block), WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human IL11.

P20809

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "FuncSNeutBlock" : {"fullname" : "Functional Studies (Neut/Block)", "shortname":"FuncS (Neut/Block)"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>", "FuncSNeutBlock-species-checked": "guaranteed", "FuncSNeutBlock-species-dilution-info": "", "FuncSNeutBlock-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Purification notes

The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and 0.2 µm filtered.

Storage buffer

Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed : 2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and IL11RA activates a signaling cascade that promotes cell proliferation (PubMed : 12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. The interaction with the membrane-bound IL11RA and IL6ST stimulates 'classic signaling', whereas the binding of IL11 and soluble IL11RA to IL6ST stimulates 'trans-signaling' (PubMed : 30279168).

See full target information IL11

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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Journal of experimental & clinical cancer research : CR 43:67 PubMed38429845

2024

Single-cell deconvolution algorithms analysis unveils autocrine IL11-mediated resistance to docetaxel in prostate cancer via activation of the JAK1/STAT4 pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Bisheng Cheng,Lingfeng Li,Tianlong Luo,Qiong Wang,Yong Luo,Shoumin Bai,Kaiwen Li,Yiming Lai,Hai Huang

Theranostics 7:3972-3988 PubMed29109792

2017

MiR-205/YAP1 in Activated Fibroblasts of Breast Tumor Promotes VEGF-independent Angiogenesis through STAT3 Signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Yan-E Du,Gang Tu,Guanglun Yang,Genyou Li,Dan Yang,Lei Lang,Lei Xi,Kexin Sun,Yanlin Chen,Kunxian Shu,Huadong Liao,Manran Liu,Yixuan Hou

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-IL-11 antibody [MM0361-9T27]

Western blot - Anti-IL-11 antibody [MM0361-9T27] (AB89887)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

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Reactivity data

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (2)

Product promise