AB39418

Anti-IL-13 receptor alpha 1 antibody [GM1E7]

Name: Anti-IL-13 receptor alpha 1 antibody [GM1E7] (ab39418) | Abcam
Brand: Abcam Limited
SKU: AB39418

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(2 Publications)

Mouse Monoclonal IL-13 receptor alpha 1 antibody. Carrier free. Suitable for Flow Cyt, ICC/IF and reacts with Transfected cell line samples. Cited in 2 publications.

View Alternative Names

CD213a1, IL13R, IL13RA, IL13RA1, Interleukin-13 receptor subunit alpha-1, IL-13 receptor subunit alpha-1, IL-13R subunit alpha-1, IL-13R-alpha-1, IL-13RA1, Cancer/testis antigen 19, CT19

3 Images

Immunocytochemistry/ Immunofluorescence - Anti-IL-13 receptor alpha 1 antibody [GM1E7] (AB39418)

ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-IL-13 receptor alpha 1 antibody [GM1E7] (AB39418)

Immunofluorescence staining of CHO cells using ab39418 at 1 μg/10⁶ cells. CHO cells were transiently transfected with an expression vector encoding IL13-R. Binding of ab39418 was visualized with a FITC-conjugated secondary antibody (green). Actin filaments are labeled with Alexa Fluor-555 Phalloidin (red). Cell nuclei are stained with DAPI (blue).

Flow Cytometry - Anti-IL-13 receptor alpha 1 antibody [GM1E7] (AB39418)

Flow Cyt

Supplier Data

Flow Cytometry - Anti-IL-13 receptor alpha 1 antibody [GM1E7] (AB39418)

Flow cytometric analysis of BOSC23 cells using ab39418. BOSC23 cells were transiently transfected with an expression vector encoding either IL13-R (red curve) or an irrelevant protein (control transfectant : black curve). Binding of ab39418 was detected with a PE-conjugated secondary antibody. A positive signal was obtained only with IL13-R transfected cells.

Flow Cyt

Unknown

Flow Cytometry - Anti-IL-13 receptor alpha 1 antibody [GM1E7] (AB39418)

Specificity testing of ab39418. BOSC cells were transiently transfected with an expression vector encoding either the extracellular domain of IL-13Rα1 or an irrelevant protein. Expression of the constructs was tested with an anti-tag monoclonal antibody (B, green curves), an irrelevant monoclonal antibody served as negative control (bluecurves). For specificity testing (A), purified ab39418 was tested on both the IL-13Rα1 (red curve) and the irrelevant protein trans-fectants (green curve). A posi-tive signal was obtained only with IL-13Rα1 transfected cells.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

GM1E7

Isotype

IgG1

Carrier free

Yes

Applications

ICC/IF, Flow Cyt

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

Specificity

The antibody recognises IL-13 Receptor 1 alpha transiently expressed on the cell surface of transfected BOSC cells as well as the native protein on monocytes.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Transfected cell line": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1.2 µg for 10^6 Cells", "FlowCyt-species-notes": "<p><a href='/en-us/products/primary-antibodies/mouse-igg1-kappa-monoclonal-15-6e10a7-isotype-control-ab170190'>ab170190</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": " for 10^6 Cells", "ICCIF-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Storage buffer

Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

+4°C

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity.

See full target information IL13RA1

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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Nature cardiovascular research 1:577-591 PubMed39195867

2022

Piezo1 is the cardiac mechanosensor that initiates the cardiomyocyte hypertrophic response to pressure overload in adult mice.

Applications

Unspecified application

Species

Unspecified reactive species

Ze-Yan Yu,Hutao Gong,Scott Kesteven,Yang Guo,Jianxin Wu,Jinyuan Vero Li,Delfine Cheng,Zijing Zhou,Siiri E Iismaa,Xenia Kaidonis,Robert M Graham,Charles D Cox,Michael P Feneley,Boris Martinac

Journal for immunotherapy of cancer 8: PubMed32616554

2020

Fibroblast activation protein-targeted-4-1BB ligand agonist amplifies effector functions of intratumoral T cells in human cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Marta Trüb,Franziska Uhlenbrock,Christina Claus,Petra Herzig,Martin Thelen,Vaios Karanikas,Marina Bacac,Maria Amann,Rosemarie Albrecht,Claudia Ferrara-Koller,Daniela Thommen,Sacha Rothschield,Spasenija Savic Prince,Kirsten D Mertz,Gieri Cathomas,Robert Rosenberg,Viola Heinzelmann-Schwarz,Mark Wiese,Didier Lardinois,Pablo Umana,Christian Klein,Heinz Laubli,Abhishek S Kashyap,Alfred Zippelius

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-IL-13 receptor alpha 1 antibody [GM1E7]

Immunocytochemistry/ Immunofluorescence - Anti-IL-13 receptor alpha 1 antibody [GM1E7] (AB39418)

Flow Cytometry - Anti-IL-13 receptor alpha 1 antibody [GM1E7] (AB39418)

Flow Cytometry - Anti-IL-13 receptor alpha 1 antibody [GM1E7] (AB39418)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Applications

Immunogen

Specificity

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Product protocols

Target data

Publications (2)

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