AB91270

Anti-IL-15RA antibody [JM7A4]

Name: Anti-IL-15RA antibody [JM7A4] (ab91270) | Abcam
Brand: Abcam Limited
SKU: AB91270

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(4 Publications)

Mouse Monoclonal IL-15RA antibody. Suitable for IP, Flow Cyt, WB and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human IL15RA.

View Alternative Names

CD215, Interleukin-15 receptor subunit alpha, IL-15 receptor subunit alpha, IL-15R-alpha, IL-15RA, IL15RA

1 Images

Flow Cytometry - Anti-IL-15RA antibody [JM7A4] (AB91270)

Flow Cyt

Unknown

Flow Cytometry - Anti-IL-15RA antibody [JM7A4] (AB91270)

ab91270 staining IL-15RA in normal Human PBMCs by Flow cytometry.
Normal Human PBMCs were isolated, and cultured in standard conditions for 3 hours. Non adherent cells were removed from culture, and remaining cells were stimulated with LPS and IFN-gamma for 24 hours.
Open/green histogram; stained with 0.25 μg of Purified Mouse IgG2b Isotype Control
Closed/blue histogram; stained with 0.25 μg of ab91270.
Detection utilised Biotin Anti-Mouse IgG and SAv-PE.
Cells in the large scatter population were used for analysis.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

JM7A4

Isotype

IgG2b

Carrier free

Reacts with

Human

Applications

Flow Cyt, WB, IP

applications

Immunogen

Recombinant Full Length Protein corresponding to Human IL15RA.

Q13261

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "0.5 µg for 10^6 Cells", "FlowCyt-species-notes": "<a href='/en-us/products/primary-antibodies/mouse-igg2b-kappa-monoclonal-7e10g10-isotype-control-ab170192'>ab170192</a> - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody.", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Purification notes

ab91270 is affinity purified

Storage buffer

pH: 7.2 Preservative: 0.09% Sodium azide Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

High-affinity receptor for interleukin-15 (PubMed : 8530383). Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells (By similarity). In neutrophils, binds and activates kinase SYK in response to IL15 stimulation (PubMed : 15123770). In neutrophils, required for IL15-induced phagocytosis in a SYK-dependent manner (PubMed : 15123770). Expression of different isoforms may alter or interfere with signal transduction (PubMed : 10480910).. Isoform 5. Does not bind IL15.. Isoform 6. Does not bind IL15.. Isoform 7. Does not bind IL15.. Isoform 8. Does not bind IL15.

See full target information IL15RA

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Publications (4)

Recent publications for all applications. Explore the full list and refine your search

International journal of molecular sciences 26: PubMed40869132

2025

IL-15 Promotes the Survival of Anti-Inflammatory (M2), Immunoinhibitory (IL-10+) Dermal Macrophages in Human Eyelid Skin Under IFNγ-Dominated Inflammatory Conditions.

Applications

Unspecified application

Species

Unspecified reactive species

Dana-Lee Demetrius,Sofia M Perez,Takahiro Suzuki,Jennifer Gherardini,Wendy Lee,Jérémy Chéret,Ralf Paus

Journal of immunology (Baltimore, Md. : 1950) 203:676-685 PubMed31201235

2019

CD137 (4-1BB) Engagement Fine-Tunes Synergistic IL-15- and IL-21-Driven NK Cell Proliferation.

Applications

Unspecified application

Species

Unspecified reactive species

Laurent Vidard,Christine Dureuil,Jérémy Baudhuin,Lionel Vescovi,Laurence Durand,Véronique Sierra,Eric Parmantier

Proceedings of the National Academy of Sciences of 101:11082-7 PubMed15263076

2004

IL-2 and IL-15 receptor alpha-subunits are coexpressed in a supramolecular receptor cluster in lipid rafts of T cells.

Applications

Unspecified application

Species

Unspecified reactive species

György Vámosi,Andrea Bodnár,György Vereb,Attila Jenei,Carolyn K Goldman,Jörg Langowski,Katalin Tóth,László Mátyus,János Szöllösi,Thomas A Waldmann,Sándor Damjanovich

Immunity 17:537-47 PubMed12433361

2002

IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells.

Applications

Unspecified application

Species

Unspecified reactive species

Sigrid Dubois,Jennifer Mariner,Thomas A Waldmann,Yutaka Tagaya

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-IL-15RA antibody [JM7A4]

Flow Cytometry - Anti-IL-15RA antibody [JM7A4] (AB91270)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

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Reactivity data

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Storage information

Product protocols

Target data

Publications (4)

Product promise