AB180792

Anti-IL-16 antibody

Name: Anti-IL-16 antibody (ab180792) | Abcam
Brand: Abcam Limited
SKU: AB180792

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(7 Publications)

Rabbit Polyclonal IL-16 antibody. Suitable for WB, ICC/IF and reacts with Human, Mouse samples. Cited in 7 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human IL16.

View Alternative Names

Pro-interleukin-16, IL16

2 Images

Immunocytochemistry/ Immunofluorescence - Anti-IL-16 antibody (AB180792)

ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-IL-16 antibody (AB180792)

Immunocytochemistry/Immunofluorescence analysis of U2OS cells using ab180792. Blue DAPI for nuclear staining.

Supplier Data

Western blot - Anti-IL-16 antibody (AB180792)

All lanes:

Western blot - Anti-IL-16 antibody (ab180792) at 1/500 dilution

Lane 1:

A549 cell line extract

Lane 2:

Jurkat cell line extract

Lane 3:

Mouse brain extract

Predicted band size: 142 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Mouse, Human

Applications

ICC/IF, WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human IL16.

Q14005

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.3 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.. Isoform 1. May act as a scaffolding protein that anchors ion channels in the membrane.. Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.

See full target information IL16

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Publications (7)

Recent publications for all applications. Explore the full list and refine your search

Degenerative neurological and neuromuscular disease 15:81-94 PubMed40937143

2025

TP73-AS1 Regulates MPP+-Induced Cell Inflammation and Apoptosis in SH-SY5Y Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Xue Zhang,Li Xue,Haiyan Li,Xiaolong Yu,Kaixin Dou,Anmu Xie

Cell death & disease 15:103 PubMed38291041

2024

Neutralizing IL-16 enhances the efficacy of targeting Aurora-A therapy in colorectal cancer with high lymphocyte infiltration through restoring anti-tumor immunity.

Applications

Unspecified application

Species

Unspecified reactive species

Shiang-Jie Yang,Sheng-Tsung Chang,Kung-Chao Chang,Bo-Wen Lin,Kwang-Yu Chang,Yao-Wen Liu,Ming-Derg Lai,Liang-Yi Hung

Bioengineered 13:1025-1038 PubMed34968167

2021

microRNA-128-3p inhibits CD4+ regulatory T cells enrichment by targeting interleukin 16 in gastric cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Weidan Fang,Chao Shi,Yiting Wang,Jianping Song,Ling Zhang

Immunology 157:257-267 PubMed31120548

2019

Interleukin-16 aggravates ovalbumin-induced allergic inflammation by enhancing Th2 and Th17 cytokine production in a mouse model.

Applications

Unspecified application

Species

Unspecified reactive species

Chunxia Li,Jun Dai,Guanjun Dong,Qun Ma,Zhihua Li,Hui Zhang,Fenglian Yan,Junfeng Zhang,Bo Wang,Hui Shi,Yuzhen Zhu,Xiaoying Yao,Chuanping Si,Huabao Xiong

Antioxidants & redox signaling 31:39-58 PubMed30450923

2018

NADPH Oxidase 4 Regulates Inflammation in Ischemic Heart Failure: Role of Soluble Epoxide Hydrolase.

Applications

Unspecified application

Species

Unspecified reactive species

Mark D Stevenson,Chandrika Canugovi,Aleksandr E Vendrov,Takayuki Hayami,Dawn E Bowles,Karl-Heinz Krause,Nageswara R Madamanchi,Marschall S Runge

Molecular therapy oncolytics 10:40-47 PubMed30109259

2018

Overexpression of microRNA-34a Attenuates Proliferation and Induces Apoptosis in Pituitary Adenoma Cells via SOX7.

Applications

Unspecified application

Species

Unspecified reactive species

Zijiang Yang,Ting Zhang,Qiping Wang,Heng Gao

Molecular medicine reports 16:9143-9148 PubMed28990054

2017

Diagnostic and prognostic value of serum interleukin‑16 in patients with gastric cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Hongyun Yang,Yanyan Han,Lele Wu,Chaojun Wu

View all publications

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