Rabbit Polyclonal IL-16 antibody. Suitable for WB, ICC/IF and reacts with Human, Mouse samples. Cited in 5 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human IL16.
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Publications
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- Bioengineered 13:1025-10382021microRNA-128-3p inhibits CD4+ regulatory T cells enrichment by targeting interleukin 16 in gastric cancer.Applications:Unspecified applicationReactive species:Unspecified reactive speciesWeidan Fang,Chao Shi,Yiting Wang,Jianping Song,Ling ZhangPubMed 34968167
- Immunology 157:257-2672019Interleukin-16 aggravates ovalbumin-induced allergic inflammation by enhancing Th2 and Th17 cytokine production in a mouse model.Applications:Unspecified applicationReactive species:Unspecified reactive speciesChunxia Li,Jun Dai,Guanjun Dong,Qun Ma,Zhihua Li,Hui Zhang,Fenglian Yan,Junfeng Zhang,Bo Wang,Hui Shi,Yuzhen Zhu,Xiaoying Yao,Chuanping Si,Huabao XiongPubMed 31120548
- Antioxidants & redox signaling 31:39-582018NADPH Oxidase 4 Regulates Inflammation in Ischemic Heart Failure: Role of Soluble Epoxide Hydrolase.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMark D Stevenson,Chandrika Canugovi,Aleksandr E Vendrov,Takayuki Hayami,Dawn E Bowles,Karl-Heinz Krause,Nageswara R Madamanchi,Marschall S RungePubMed 30450923
- Molecular therapy oncolytics 10:40-472018Overexpression of microRNA-34a Attenuates Proliferation and Induces Apoptosis in Pituitary Adenoma Cells via SOX7.Applications:Unspecified applicationReactive species:Unspecified reactive speciesZijiang Yang et. al.PubMed 30109259
- Molecular medicine reports 16:9143-91482017Diagnostic and prognostic value of serum interleukin‑16 in patients with gastric cancer.Applications:Unspecified applicationReactive species:Unspecified reactive speciesHongyun Yang et. al.PubMed 28990054
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.3
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Recombinant Full Length Protein corresponding to Human IL16. Database link Q14005
Reactivity data
Select an application| WB | ICC/IF | |
|---|---|---|
| Human | Tested | Tested |
| Mouse | Tested | Expected |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/500.00000 - 1/2000.00000 | Notes - |
Species Mouse | Dilution info 1/500.00000 - 1/2000.00000 | Notes - |
ICC/IF
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info - | Notes - |
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info Use at an assay dependent concentration. | Notes - |
Associated Products
Select an associated product type
3 products for Alternative Product
Target data
Function
Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. Isoform 1. May act as a scaffolding protein that anchors ion channels in the membrane. Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.
Alternative names
Pro-interleukin-16, IL16
Recommended products
Rabbit Polyclonal IL-16 antibody. Suitable for WB, ICC/IF and reacts with Human, Mouse samples. Cited in 5 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human IL16.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.3
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Recombinant Full Length Protein corresponding to Human IL16. Database link Q14005
- Purification technique
- Affinity purification Immunogen
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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2 product images
Immunocytochemistry/ Immunofluorescence - Anti-IL-16 antibody (ab180792)
Immunocytochemistry/Immunofluorescence analysis of U2OS cells using ab180792. Blue DAPI for nuclear staining.
Western blot - Anti-IL-16 antibody (ab180792)
All lanes: Western blot - Anti-IL-16 antibody (ab180792) at 1/500 dilution
Lane 1: A549 cell line extract
Lane 2: Jurkat cell line extract
Lane 3: Mouse brain extract
Predicted band size: 142 kDa
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