Rabbit Polyclonal IL-17C antibody. Suitable for IHC-P, WB and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Recombinant Fragment Protein within Human IL17C aa 1 to C-terminus.
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Publications
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- Journal of virology 96:e01342212021Transcriptomic Landscape of Gene Expression Profiles and Pathways in Juvenile-Onset Recurrent Respiratory Papillomatosis Tumor Tissues and Human Papillomavirus 6 and 11 E6- and E7-Overexpressing Head and Neck Squamous Cell Carcinoma Cell Lines.Applications:Unspecified applicationReactive species:Unspecified reactive speciesXunyao Wu,Yang Xiao,Sihan Zhou,Yuge Wang,Jun WangPubMed 34669519
- Veterinary research 50:482019Toll-like receptor 5-mediated IL-17C expression in intestinal epithelial cells enhances epithelial host defense against F4 ETEC infection.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYu Luo et. al.PubMed 31221216
- Cytokine 65:236-442013Interleukin 17A evoked mucosal damage is attenuated by cannabidiol and anandamide in a human colonic explant model.
- Internal and emergency medicine 8:317-252011Mucosal changes induced by ischemia-reperfusion injury in a jejunal loop transplanted in oropharynx.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAntonio Di Sabatino,Laura Brunetti,Paolo Biancheri,Rachele Ciccocioppo,Marco Guerci,Claudia Casella,Francesca Vidali,Thomas T MacDonald,Marco Benazzo,Gino R CorazzaPubMed 21553237
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Recombinant Fragment Protein within Human IL17C aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link Q9P0M4
Reactivity data
Select an application| IHC-P | WB | |
|---|---|---|
| Human | Tested | Tested |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/100.00000 - 1/1000.00000 | Notes Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/500.00000 - 1/3000.00000 | Notes - |
Target data
Function
Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and pro-inflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes. Depending on the type of insult, may have both protective and pathogenic properties, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype. Enhanced IL17C/IL17RE signaling may also lead to greater susceptibility to autoimmune diseases.
Alternative names
UNQ561/PRO1122, IL17C, Interleukin-17C, IL-17C, Cytokine CX2
Recommended products
Rabbit Polyclonal IL-17C antibody. Suitable for IHC-P, WB and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Recombinant Fragment Protein within Human IL17C aa 1 to C-terminus.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Recombinant Fragment Protein within Human IL17C aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link Q9P0M4
- Purification technique
- Affinity purification Immunogen
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
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2 product images
Western blot - Anti-IL-17C antibody (ab153896)
12% SDS PAGE
All lanes: Western blot - Anti-IL-17C antibody (ab153896) at 1/1000 dilution
All lanes: A549 whole cell lysate at 30 µg
Predicted band size: 22 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-17C antibody (ab153896)
Immunohistochemical analysis of paraffin-embedded Human colon tissue labeling IL17C with ab153896 at 1/250 dilution.
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