AB154187

Anti-IL-19 antibody [EPNCIR168]

RabMAb
Recombinant
What is this?

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(6 Publications)

Rabbit Recombinant Monoclonal IL-19 antibody. Suitable for WB, ICC/IF and reacts with Mouse, Human samples. Cited in 6 publications.

View Alternative Names

ZMDA1, IL19, Interleukin-19, IL-19, Melanoma differentiation-associated protein-like protein, NG.1

2 Images

Immunocytochemistry/ Immunofluorescence - Anti-IL-19 antibody [EPNCIR168] (AB154187)

ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-IL-19 antibody [EPNCIR168] (AB154187)

Immunofluorescent analysis of U937 cells labeling IL19 with ab154187 at 1/50 dilution

Unknown

Western blot - Anti-IL-19 antibody [EPNCIR168] (AB154187)

All lanes:

Western blot - Anti-IL-19 antibody [EPNCIR168] (ab154187) at 1/1000 dilution

All lanes:

Mouse IL19 recombinant protein at 0.01 µg

Predicted band size: 20 kDa

false

Carrier free

Anti-IL-19 antibody [EPNCIR168] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPNCIR168

Isotype

IgG

Carrier free

Reacts with

Mouse, Human

Applications

ICC/IF, WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/50 - 1/100", "ICCIF-species-notes": "" }, "Mouse": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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Product details

This antibody was developed as part of a collaboration between the National Cancer Institute's Center for Cancer Research and the lab of Juergen Mueller. View antibodies from NCI Center for Cancer Research Collaboration.

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

Species reactivity
Rat: We have preliminary internal testing data to indicate this antibody may not react with this species.
Please contact us for more information.

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Properties and storage information

Form

Liquid

Purity

Tissue culture supernatant

Storage buffer

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Cytokine that functions as an anti-inflammatory and proangiogenic factor (PubMed : 34932373). Polarizes adaptive immunity to an anti-inflammatory phenotype through induction of T-helper 2 responses by both down-regulation of IFN-gamma and up-regulation of IL4 and IL13 (PubMed : 16365913). Produced by osteocytes, stimulates granulopoiesis and neutrophil formation (By similarity). Exerts its biological effect through a receptor complex consisting of a heterodimer of IL20RA and IL20RB (PubMed : 12351624). In turn, activates the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) pathway, and importantly, STAT3 (PubMed : 11564763).

See full target information IL19

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Publications (6)

Recent publications for all applications. Explore the full list and refine your search

Cells 12: PubMed37887308

2023

IL-20 Cytokines Are Involved in the Repair of Airway Epithelial Barrier: Implication in Exposure to Cigarette Smoke and in COPD Pathology.

Applications

Unspecified application

Species

Unspecified reactive species

Olivia Barada,Sophie Salomé-Desnoulez,Fahima Madouri,Gaëtan Deslée,Christelle Coraux,Philippe Gosset,Muriel Pichavant

The Journal of clinical investigation 132: PubMed36006737

2022

IL-20RB mediates tumoral response to osteoclastic niches and promotes bone metastasis of lung cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Yunfei He,Wenqian Luo,Yingjie Liu,Yuan Wang,Chengxin Ma,Qiuyao Wu,Pu Tian,Dasa He,Zhenchang Jia,Xianzhe Lv,Yu-Shui Ma,Haitang Yang,Ke Xu,Xue Zhang,Yansen Xiao,Peiyuan Zhang,Yajun Liang,Da Fu,Feng Yao,Guohong Hu

Mediators of inflammation 2022:6755407 PubMed35281428

2022

Interleukin-19 Aggravates Pulmonary Fibrosis via Activating Fibroblast through TGF-/Smad Pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Yu Wang,Sibo Sun,Kai Wang,Mingjiong Zhang,Min Li,Yumin Zan,Qiqing Huang,Shuangshuang Wu,Weihong Zhao,Wei Xu,Jianqing Wu

Biomedicines 9: PubMed34944654

2021

IL-20 Cytokines Are Involved in Epithelial Lesions Associated with Virus-Induced COPD Exacerbation in Mice.

Applications

Unspecified application

Species

Unspecified reactive species

Mélina Le Roux,Anaïs Ollivier,Gwenola Kervoaze,Timothé Beke,Laurent Gillet,Muriel Pichavant,Philippe Gosset

Bioscience, biotechnology, and biochemistry 83:1284-1288 PubMed30915898

2019

LncRNA CASC11 improves atherosclerosis by downregulating IL-9 and regulating vascular smooth muscle cell apoptosis and proliferation.

Applications

Unspecified application

Species

Unspecified reactive species

Kaiyu Tao,Zhanglong Hu,Yigong Zhang,Daming Jiang,Haifeng Cheng

EBioMedicine 37:417-427 PubMed30361066

2018

Production of Interleukin-20 cytokines limits bacterial clearance and lung inflammation during infection by Streptococcus pneumoniae.

Applications

Unspecified application

Species

Unspecified reactive species

Fahima Madouri,Olivia Barada,Gwenola Kervoaze,François Trottein,Muriel Pichavant,Philippe Gosset

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-IL-19 antibody [EPNCIR168]

Immunocytochemistry/ Immunofluorescence - Anti-IL-19 antibody [EPNCIR168] (AB154187)

Western blot - Anti-IL-19 antibody [EPNCIR168] (AB154187)

Related conjugates and formulations (1)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Product details

Properties and storage information

Form

Purity

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Product protocols

Target data

Publications (6)

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