AB5980

Anti-IL-21R antibody

Name: Anti-IL-21R antibody (ab5980) | Abcam
Brand: Abcam Limited
SKU: AB5980

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(9 Publications)

Rabbit Polyclonal IL-21R antibody. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 9 publications. Immunogen corresponding to Synthetic Peptide within Human IL21R aa 50-150.

View Alternative Names

CD360, NILR, UNQ3121/PRO10273, IL21R, Interleukin-21 receptor, IL-21 receptor, IL-21R, Novel interleukin receptor

2 Images

Immunocytochemistry/ Immunofluorescence - Anti-IL-21R antibody (AB5980)

ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-IL-21R antibody (AB5980)

Immunocytochemistry/Immunofluorescence labelling A431 cells with ab5980 at 20μg/ml.

Supplier Data

Western blot - Anti-IL-21R antibody (AB5980)

Lane 1:

Western blot - Anti-IL-21R antibody (ab5980) at 1 µg/mL

Lane 2:

Western blot - Anti-IL-21R antibody (ab5980) at 2 µg/mL

All lanes:

HepG2 cell lysate

Predicted band size: 59 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

ICC/IF, WB

applications

Immunogen

Synthetic Peptide within Human IL21R aa 50-150. The exact immunogen used to generate this antibody is proprietary information.

Q9HBE5

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1-2 µg/mL", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "20 µg/mL", "ICCIF-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle|Stable for 12 months at -20°C

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

This is a receptor for interleukin-21.

See full target information IL21R

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Publications (9)

Recent publications for all applications. Explore the full list and refine your search

Applied biochemistry and biotechnology 196:6189-6199 PubMed38224392

2024

Th9 Cytokines Inhibit Proliferation, Promote Apoptosis, and Immune Escape in Thyroid Carcinoma Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Xinyu Ying,Xinyi Ma,Ziru Yang,Bo Zhou

Journal of inflammation research 14:5051-5058 PubMed34629885

2021

Expression and Correlation of IgG4 and IL-21 in Collagen-Induced Arthritis Rats.

Applications

Unspecified application

Species

Unspecified reactive species

Zhen-Yi Long,Yi-Feng Zhou,Hao Yuan,Ya-Meng Peng,Si-Xian Wu,Fang Peng

International journal of medical sciences 17:3065-3072 PubMed33173427

2020

IL-21 promotes osteoblastic differentiation of human valvular interstitial cells through the JAK3/STAT3 pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Zongtao Liu,Yixuan Wang,Jiawei Shi,Si Chen,Li Xu,Fei Li,Nianguo Dong

Aging 12:18396-18414 PubMed32991326

2020

Elevated serum IL-21 levels are associated with stable immune status in kidney transplant recipients and a mouse model of kidney transplantation.

Applications

Unspecified application

Species

Unspecified reactive species

Luying Guo,Junhao Lv,Jian Zhang,Hao Deng,Shi Feng,Shuaihui Liu,Pengpeng Yan,Jingyi Zhou,Hui Chen,Meifang Wang,Qin Zhou,Huiping Wang,Jianghua Chen,Yu Kuang,Jia Shen,Rending Wang

International journal of molecular medicine 44:1697-1706 PubMed31573051

2019

IL‑21/IL‑21R inhibit tumor growth and invasion in non‑small cell lung cancer cells via suppressing Wnt/β‑catenin signaling and PD‑L1 expression.

Applications

Unspecified application

Species

Unspecified reactive species

Dan Xue,Ping Yang,Qiongying Wei,Xiaoping Li,Lan Lin,Tingyan Lin

International journal of oncology 55:1077-1089 PubMed31545408

2019

Genome profiling revealed the activation of IL2RG/JAK3/STAT5 in peripheral T‑cell lymphoma expressing the ITK‑SYK fusion gene.

Applications

Unspecified application

Species

Unspecified reactive species

Lei-Lei Zhang,Hua-Xiong Pan,Yi-Xuan Wang,Tao Guo,Lin Liu

International journal of oncology 54:7-16 PubMed30387833

2018

IL-21R functions as an oncogenic factor and is regulated by the lncRNA MALAT1/miR-125a-3p axis in gastric cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Lei Yan,Jing Zhang,Dong Guo,Ji Ma,Shao-Feng Shui,Xin-Wei Han

International journal of molecular medicine 38:1125-34 PubMed27599586

2016

Interleukin-21 promotes osteoclastogenesis in RAW264.7 cells through the PI3K/AKT signaling pathway independently of RANKL.

Applications

Unspecified application

Species

Unspecified reactive species

Rui Xing,Yingjian Zhang,Changhong Li,Lin Sun,Lin Yang,Jinxia Zhao,Xiangyuan Liu

Vascular medicine (London, England) 21:99-104 PubMed26705256

2015

Endothelial interleukin-21 receptor up-regulation in peripheral artery disease.

Applications

Unspecified application

Species

Unspecified reactive species

Tao Wang,Alexis Cunningham,Kevin Houston,Aditya M Sharma,Lingdan Chen,Ayotunde O Dokun,R John Lye,Rosanne Spolski,Warren J Leonard,Brian H Annex

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-IL-21R antibody

Immunocytochemistry/ Immunofluorescence - Anti-IL-21R antibody (AB5980)

Western blot - Anti-IL-21R antibody (AB5980)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (9)

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Product promise