JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB181007

Anti-IL-22 antibody

Be the first to review this product! Submit a review

|

(3 Publications)

Rabbit Polyclonal IL-22 antibody. Suitable for WB and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Synthetic Peptide within Human IL22.

View Alternative Names

ILTIF, ZCYTO18, UNQ3099/PRO10096, IL22, Interleukin-22, IL-22, Cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor, IL-TIF

1 Images
Western blot - Anti-IL-22 antibody (AB181007)
  • WB

Supplier Data

Western blot - Anti-IL-22 antibody (AB181007)

All lanes:

Western blot - Anti-IL-22 antibody (ab181007) at 1 µg

Lane 1:

HeLa cell lysate at 15 µg with absent

Lane 2:

HeLa cell lysate at 15 µg with present

Predicted band size: 20 kDa

Observed band size: 25 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Synthetic Peptide within Human IL22. The exact immunogen used to generate this antibody is proprietary information.

Q9GZX6

style
left-column

Alternative Products

Primary Antibodies

AB134035

Anti-IL-22 antibody [IMG8F11E2]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-22 antibody [IMG8F11E2] (AB134035)

  • 3
  • 1
Primary Antibodies

AB133545

Anti-IL-22 antibody [EPR5741]

RabMAb|Recombinant

Western blot - Anti-IL-22 antibody [EPR5741] (AB133545)

  • 0
  • 0

Complementary Products

Assay Kits

AB216170

Human IL-22 ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Human IL-22 ELISA Kit (AB216170)

  • 0
  • 0
Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Primary Antibodies

AB233706

Anti-IL-6 antibody [EPR21711]

RabMAb|Recombinant|KO Validated

Immunocytochemistry/ Immunofluorescence - Anti-IL-6 antibody [EPR21711] (AB233706)

  • 5
  • 1
Primary Antibodies

AB203211

Anti-IL22 RA2/IL-22BP antibody

Flow Cytometry - Anti-IL22 RA2/IL-22BP antibody (AB203211)

  • 0
  • 0
Primary Antibodies

AB245076

Anti-IL-28A antibody [EPR20974-48] - BSA and Azide free (Detector)

RabMAb|Recombinant

Sandwich ELISA - Anti-IL-28A antibody [EPR20974-48] - BSA and Azide free (Detector) (AB245076)

  • 0
  • 0
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1-2 µg/mL", "WB-species-notes": "<p></p>" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

Cytokine that plays a critical role in modulating tissue responses during inflammation (PubMed : 17204547). Plays an essential role in the regeneration of epithelial cells to maintain barrier function after injury and for the prevention of further tissue damage (PubMed : 17204547). Unlike most of the cytokines, has no effect on immune cells. Signals through a heterodimeric receptor composed of two subunits, the specific receptor IL22RA1 which is present on non-immune cells in many organs and the shared subunit IL10RB (PubMed : 10875937, PubMed : 18599299). Ligation of IL22RA1 with IL22 induces activation of the tyrosine kinases JAK1 and TYK2, which in turn activates STAT3. In turn, promotes cell survival and proliferation through STAT3, ERK1/2 and PI3K/AKT pathways (PubMed : 25793261, PubMed : 31311100). Promotes phosphorylation of GSK3B at 'Ser-9' and CTTN (By similarity). Promotes epithelial cell spreading (By similarity).
See full target information IL22
style
left-column

Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Clinical and translational medicine 11:e509 PubMed34459137

2021

Protective function of interleukin-22 in pulmonary fibrosis.

Applications

Unspecified application

Species

Unspecified reactive species

Peiyu Gu,Dandan Wang,Ji Zhang,Xin Wang,Zhiyong Chen,Lina Gu,Mengying Liu,Fanqing Meng,Jun Yang,Hourong Cai,Yonglong Xiao,Yin Chen,Mengshu Cao

Experimental and therapeutic medicine 19:1379-1387 PubMed32010312

2020

Interleukin-22 modulates cisplatin sensitivity of osteosarcoma cells by regulating the STAT3 signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Zhiqiang Li,Renjie Xu,Xiangxin Zhang,Jun Shen,Guangxiang Chen,Tianming Zou,Xiao Yu

Scientific reports 7:12044 PubMed28935920

2017

Inhibition of PDE2 reverses beta amyloid induced memory impairment through regulation of PKA/PKG-dependent neuro-inflammatory and apoptotic pathways.

Applications

Unspecified application

Species

Unspecified reactive species

Li Wang,Yilixiati Xiaokaiti,Gang Wang,Xiaoxiao Xu,Ling Chen,Xianfeng Huang,Li Liu,Jianchun Pan,Shuqun Hu,Zhuoyou Chen,Ying Xu
View all publications
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com