Rabbit Polyclonal IL-22RA1 antibody. Suitable for ICC, WB, IHC-P, ICC/IF and reacts with Human, Rat samples. Cited in 21 publications. Immunogen corresponding to Synthetic Peptide within Human IL22RA1 aa 1-50.
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- PloS one 18:e02869072023Endogenous interleukin-22 prevents cardiac rupture after myocardial infarction in mice.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMai Yamamoto,Hideo Yasukawa,Jinya Takahashi,Shoichiro Nohara,Tomoko Sasaki,Kodai Shibao,Daiki Akagaki,Kota Okabe,Toshiyuki Yanai,Tatsuhiro Shibata,Yoshihiro FukumotoPubMed 37319277
- Journal of immunology (Baltimore, Md. : 1950) 209:1768-17772022Th17-Derived Cytokines Synergistically Enhance IL-17C Production by the Colonic Epithelium.Applications:Unspecified applicationReactive species:Unspecified reactive speciesStephanie M Swedik,Abson Madola,Michelle A Cruz,Braulio J Llorens-Bonilla,Alan D LevinePubMed 36130829
- Disease markers 2022:43519492022Folate Receptor 4-Expressing T cell Is Associated with Disease-Free Survival in Patients with Esophageal Squamous Cell Carcinoma.Applications:Unspecified applicationReactive species:Unspecified reactive speciesXiangmei Zhang,Qi Zhao,Miao Cao,Xinhui Li,Xin Chen,Ming He,Yunjiang Liu,Jidong ZhaoPubMed 35756495
- Frontiers in pharmacology 12:6578272021Microbiome-Metabolomics Analysis Reveals the Protection Mechanism of -Ketoacid on Adenine-Induced Chronic Kidney Disease in Rats.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYenan Mo,Huang Sun,Lei Zhang,Wenjia Geng,Lixin Wang,Chuan Zou,Yuchi Wu,Chunlan Ji,Xusheng Liu,Zhaoyu LuPubMed 34045965
- EBioMedicine 64:1032132021Interleukin-24 protects against liver injury in mouse models.Applications:Unspecified applicationReactive species:Unspecified reactive speciesHsiao-Hsuan Wang et. al.PubMed 33508745
- Cancer biotherapy & radiopharmaceuticals 36:160-1662020Tumor Cells Interleukin-22 Expression Associates with Elevated Tumor-Associated Macrophages Infiltrating and Poor Prognosis in Patients with Breast Cancer.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJidong Zhao,Hongzhang Liu,Xiangmei Zhang,Wenqing Zhang,Li Liu,Yang Yu,Shuguang Ren,Qing Yang,Beichen Liu,Jingping Li,Xinhui Li,Yunjiang Liu,Liyan ZhaoPubMed 33090014
- Experimental and therapeutic medicine 20:2148-21562020IL-22/IL-22R1 promotes proliferation and collagen synthesis of MRC-5 cells via the JAK/STAT3 signaling pathway and regulates airway subepithelial fibrosis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJuan Liu et. al.PubMed 32765690
- Journal of the American Heart Association 9:e0148142020Interleukin-22 Directly Activates Myocardial STAT3 (Signal Transducer and Activator of Transcription-3) Signaling Pathway and Prevents Myocardial Ischemia Reperfusion Injury.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJinya Takahashi et. al.PubMed 32301368
- Gastroenterology 158:1417-1432.e112019Interleukin 22 Signaling Regulates Acinar Cell Plasticity to Promote Pancreatic Tumor Development in Mice.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMirna Perusina Lanfranca,Yaqing Zhang,Alexander Girgis,Samantha Kasselman,Jenny Lazarus,Illona Kryczek,Lawrence Delrosario,Andrew Rhim,Lada Koneva,Maureen Sartor,Lei Sun,Christopher Halbrook,Hari Nathan,Jiaqi Shi,Howard C Crawford,Marina Pasca di Magliano,Weiping Zou,Timothy L FrankelPubMed 31843590
- World journal of gastroenterology 25:2473-24882019Interleukin-22 receptor 1 is expressed in multinucleated giant cells: A study on intestinal tuberculosis and Crohn's disease.Applications:Unspecified applicationReactive species:Unspecified reactive speciesZi-Qi Yu,Wen-Fei Wang,You-Chao Dai,Xin-Chun Chen,Jian-Yong ChenPubMed 31171891
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: PBS- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Synthetic Peptide within Human IL22RA1 aa 1-50. The exact immunogen used to generate this antibody is proprietary information. Database link Q8N6P7
Reactivity data
Select an application| ICC | WB | IHC-P | ICC/IF | |
|---|---|---|---|---|
| Human | Tested | Tested | Expected | Tested |
| Rat | Expected | Expected | Tested | Expected |
ICC
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 10 µg/mL | Notes - |
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Rat | Dilution info Use at an assay dependent concentration. | Notes - |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 0.50000-1.00000 µg/mL | Notes - |
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Rat | Dilution info Use at an assay dependent concentration. | Notes - |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Rat | Dilution info 5 µg/mL | Notes - |
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info Use at an assay dependent concentration. | Notes - |
ICC/IF
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 10 µg/mL | Notes - |
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Rat | Dilution info Use at an assay dependent concentration. | Notes - |
Associated Products
Select an associated product type
2 products for Alternative Product
Target data
Function
Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.
Alternative names
IL22R, IL22RA1, Interleukin-22 receptor subunit alpha-1, IL-22 receptor subunit alpha-1, IL-22R-alpha-1, IL-22RA1, Cytokine receptor class-II member 9, Cytokine receptor family 2 member 9, ZcytoR11, CRF2-9
Recommended products
Rabbit Polyclonal IL-22RA1 antibody. Suitable for ICC, WB, IHC-P, ICC/IF and reacts with Human, Rat samples. Cited in 21 publications. Immunogen corresponding to Synthetic Peptide within Human IL22RA1 aa 1-50.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: PBS- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Synthetic Peptide within Human IL22RA1 aa 1-50. The exact immunogen used to generate this antibody is proprietary information. Database link Q8N6P7
- Purification technique
- Affinity purification Immunogen
- Concentration
- Purification notes
IL-22RA1 Antibody is affinity chromatography purified via peptide column.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Storage information
- Avoid freeze / thaw cycle, Stable for 12 months at -20°C
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
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6 product images
Western blot - Anti-IL-22RA1 antibody (ab5984)
Lane 1: Western blot - Anti-IL-22RA1 antibody (ab5984) at 0.5 µg/mL
Lane 2: Western blot - Anti-IL-22RA1 antibody (ab5984) at 1 µg/mL
All lanes: HepG2 cell lysates
Predicted band size: 63 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-22RA1 antibody (ab5984)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of rat kidney tissue labelling IL-22RA1 with ab5984 at 5μg/ml.
Immunocytochemistry - Anti-IL-22RA1 antibody (ab5984)
Immunocytochemistry of IL-22R in HepG2 cells with IL-22RA1 antibody at 10 μg/ml.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-22RA1 antibody (ab5984)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of rat kidney tissue labelling IL-22RA1 with ab5984 at 20μg/ml.
Immunocytochemistry/ Immunofluorescence - Anti-IL-22RA1 antibody (ab5984)
Immunocytochemistry/Immunofluorescence analysis of HepG2 cells labelling IL-22RA1 with ab5984 at 10μg/ml.
Western blot - Anti-IL-22RA1 antibody (ab5984)
Western blot analysis of IL-22RA1 expression in human HepG2 cell lysate with ab5984 at 1μg /ml. Western blot analysis of IL-22R expression in human HepG2 cell lysate with ab5984 at 1μg /ml.
All lanes: Western blot - Anti-IL-22RA1 antibody (ab5984)
Predicted band size: 63 kDa
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