AB233761

Anti-IL-28A antibody [7B9A4]

Name: Anti-IL-28A antibody [7B9A4] (ab233761) | Abcam
Brand: Abcam Limited
SKU: AB233761
Price: 510 USD
Availability: InStock

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(1 Publication)

Mouse Monoclonal IFNL2 antibody. Suitable for WB, IHC-P and reacts with Recombinant full length protein - Human, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human IFNL2.

View Alternative Names

IL28A, ZCYTO20, IFNL2, Interferon lambda-2, IFN-lambda-2, Cytokine Zcyto20, Interleukin-28A, IL-28A

5 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-28A antibody [7B9A4] (AB233761)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-28A antibody [7B9A4] (AB233761)

Paraffin-embedded human esophageal cancer tissue stained for IL28A using ab233761 at 1/200 dilution in immunohistochemical analysis. DAB staining.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-28A antibody [7B9A4] (AB233761)

Paraffin-embedded human brain tissue stained for IL28A using ab233761 at 1/200 dilution in immunohistochemical analysis. DAB staining.

Supplier Data

Western blot - Anti-IL-28A antibody [7B9A4] (AB233761)

All lanes:

Western blot - Anti-IL-28A antibody [7B9A4] (ab233761) at 1/500 dilution

All lanes:

IL28A (AA: 1-200) recombinant protein

Predicted band size: 22 kDa

false

Supplier Data

Western blot - Anti-IL-28A antibody [7B9A4] (AB233761)

All lanes:

Western blot - Anti-IL-28A antibody [7B9A4] (ab233761) at 1/500 dilution

All lanes:

SK-BR-3 (Human mammary gland adenocarcinoma cell line) cell lysate

Predicted band size: 22 kDa

false

Supplier Data

Western blot - Anti-IL-28A antibody [7B9A4] (AB233761)

All lanes:

Western blot - Anti-IL-28A antibody [7B9A4] (ab233761) at 1/500 dilution

Lane 1:

HEK-293 (Human epithelial cell line from embryonic kidney) cell lysate

Lane 2:

IL28A (AA: 1-200)-hIgGFc transfected HEK-293 cell lysate.

Predicted band size: 22 kDa

false

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

7B9A4

Isotype

IgG1

Carrier free

Reacts with

Human

Applications

WB, IHC-P

applications

Immunogen

Recombinant Full Length Protein corresponding to Human IFNL2.

Q8IZJ0

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/1000", "IHCP-species-notes": "" }, "Recombinant full length protein - Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Storage buffer

Preservative: 0.05% Sodium azide Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets : is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.

See full target information IFNL2

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Immunity, inflammation and disease 10:e697 PubMed36169256

2022

Inhibiting P2Y12 receptor relieves LPS-induced inflammation and endothelial dysfunction.

Applications

Unspecified application

Species

Unspecified reactive species

Xiuxia Han

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-IL-28A antibody [7B9A4]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-28A antibody [7B9A4] (AB233761)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-28A antibody [7B9A4] (AB233761)

Western blot - Anti-IL-28A antibody [7B9A4] (AB233761)

Western blot - Anti-IL-28A antibody [7B9A4] (AB233761)

Western blot - Anti-IL-28A antibody [7B9A4] (AB233761)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (1)

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