Rabbit Polyclonal IL-36R antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Synthetic Peptide within Human IL1RL2.
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Publications
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- Investigative ophthalmology & visual science 62:102021Role of IL-36γ/IL-36R Signaling in Corneal Innate Defense Against Candida albicans Keratitis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesChenyang Dai,Rao Me,Nan Gao,Guanyu Su,Xinyi Wu,Fu-Shin X YuPubMed 33970198
- Technology in cancer research & treatment 20:15330338219952822021The Potential Role of IL1RAP on Tumor Microenvironment-Related Inflammatory Factors in Stomach Adenocarcinoma.Applications:Unspecified applicationReactive species:Unspecified reactive speciesQing Lv,Qinghua Xia,Anshu Li,Zhiyong WangPubMed 33602046
- International journal of molecular sciences 22:2020Role of IL-36 Cytokines in the Regulation of Angiogenesis Potential of Trophoblast Cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJosé M Murrieta-Coxca et. al.PubMed 33396613
- Glia 67:438-4512018Spinal IL-36γ/IL-36R participates in the maintenance of chronic inflammatory pain through astroglial JNK pathway.Applications:Unspecified applicationReactive species:Unspecified reactive speciesQian Li,Shenbin Liu,Lingling Li,Xiaoli Ji,Min Wang,Junmei ZhouPubMed 30578562
- Mucosal immunology 9:1193-2042016IL-36α expression is elevated in ulcerative colitis and promotes colonic inflammation.Applications:Unspecified applicationReactive species:Unspecified reactive speciesS E Russell et. al.PubMed 26813344
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 99% PBS- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Synthetic Peptide within Human IL1RL2. The exact immunogen used to generate this antibody is proprietary information. Database link Q9HB29
Reactivity data
Select an application| WB | IHC-P | |
|---|---|---|
| Human | Tested | Tested |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1.00000-2.00000 µg/mL | Notes - |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 5.00000-20.00000 µg/mL | Notes - |
Associated Products
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Target data
Function
Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways (By similarity). The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway.
Alternative names
IL1RRP2, IL1RL2, Interleukin-1 receptor-like 2, IL-36 receptor, Interleukin-1 receptor-related protein 2, IL-36R, IL-1Rrp2, IL1R-rp2
Recommended products
Rabbit Polyclonal IL-36R antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Synthetic Peptide within Human IL1RL2.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 99% PBS- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Synthetic Peptide within Human IL1RL2. The exact immunogen used to generate this antibody is proprietary information. Database link Q9HB29
- Purification technique
- Affinity purification Immunogen
- Specificity
ab180894 will detect all three isoforms of IL1RL2. ab180894 is predicted to not cross-react with IL1 Receptor I or ST2.
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- +4°C
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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3 product images
Western blot - Anti-IL-36R antibody (ab180894)
Lane 1: Western blot - Anti-IL-36R antibody (ab180894) at 1 µg/mL
Lane 2: Western blot - Anti-IL-36R antibody (ab180894) at 2 µg/mL
All lanes: Human small intestine lysate at 15 µg
Predicted band size: 65 kDa
Observed band size: 55 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-36R antibody (ab180894)
Immunohistochemical analysis of paraffin-embedded Human small intestine tissue labeling IL1RL2 with ab180894 at 5 μg/ml.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-36R antibody (ab180894)
Immunohistochemical analysis of paraffin-embedded Human small intestine tissue labeling IL1RL2 with ab180894 at 20 μg/ml.
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