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Rabbit Polyclonal IL-36RN antibody. Suitable for WB and reacts with Human samples. Immunogen corresponding to Synthetic Peptide within Human IL36RN.

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Images

Western blot - Anti-IL-36RN antibody (AB228532), expandable thumbnail

Key facts

Isotype
IgG
Host species
Rabbit
Storage buffer

pH: 7
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 10% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine

Form
Liquid
Clonality
Polyclonal

Immunogen

  • Synthetic Peptide within Human IL36RN. The exact immunogen used to generate this antibody is proprietary information. Database link Q9UBH0

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
WB
Human
Tested

Tested
Tested

Species
Human
Dilution info
1/500.00000 - 1/3000.00000
Notes

-

Target data

Function

Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.

Alternative names

FIL1D, IL1F5, IL1HY1, IL1L1, IL1RP3, UNQ1896/PRO4342, IL36RN, Interleukin-36 receptor antagonist protein, IL-36Ra, FIL1 delta, IL-1-related protein 3, Interleukin-1 HY1, Interleukin-1 delta, Interleukin-1 family member 5, Interleukin-1 receptor antagonist homolog 1, Interleukin-1-like protein 1, IL-1RP3, IL-1HY1, IL-1 delta, IL-1F5, IL-1ra homolog 1, IL-1L1

Recommended products

Rabbit Polyclonal IL-36RN antibody. Suitable for WB and reacts with Human samples. Immunogen corresponding to Synthetic Peptide within Human IL36RN.

Key facts

Isotype
IgG
Form
Liquid
Clonality
Polyclonal
Immunogen
  • Synthetic Peptide within Human IL36RN. The exact immunogen used to generate this antibody is proprietary information. Database link Q9UBH0
Purification technique
Affinity purification Immunogen
Concentration
Loading...

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Notes

Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.

If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.

Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.

Product promise

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1 product image

  • Western blot - Anti-IL-36RN antibody (ab228532), expandable thumbnail

    Western blot - Anti-IL-36RN antibody (ab228532)

    12% SDS-PAGE

    All lanes: Western blot - Anti-IL-36RN antibody (ab228532) at 1/500 dilution

    Lane 1: Non-transfected HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) cell lysate

    Lane 2: IL36RN-transfected HEK-293T cell lysate

    Developed using the ECL technique.

    Predicted band size: 17 kDa

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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