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AB25034

Anti-IL-5 antibody [QS-5]

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(4 Publications)

Mouse Monoclonal IL-5 antibody. Suitable for ELISA, WB, FuncS (Neut/Block), ELISPOT, IHC-Fr and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human IL5.

View Alternative Names

Interleukin-5, IL-5, B-cell differentiation factor I, Eosinophil differentiation factor, T-cell replacing factor, TRF, IL5

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

QS-5

Isotype

IgG1

Carrier free

No

Reacts with

Human

Applications

FuncS (Neut/Block), IHC-Fr, ELISPOT, WB, ELISA

applications

Immunogen

Recombinant Full Length Protein corresponding to Human IL5.

P05113

Specificity

Binds with high efficiency to natural and recombinant human IL5.

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Alternative Products

Primary Antibodies

AB9624

Anti-IL-5 antibody

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Complementary Products

Assay Kits

AB215536

Human IL-5 ELISA Kit

Recombinant|SimpleStep

ELISA - Human IL-5 ELISA Kit (AB215536)

  • 0
  • 0
Primary Antibodies

AB285053

Anti-IL-13 antibody [EPR20465-131] - BSA and Azide free (Capture)

RabMAb|Recombinant

Sandwich ELISA - Anti-IL-13 antibody [EPR20465-131] - BSA and Azide free (Capture) (AB285053)

  • 0
  • 0
Primary Antibodies

AB133575

Anti-IL-10 antibody [EPR1114]

20ul selling size|RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-IL-10 antibody [EPR1114] (AB133575)

  • 4
  • 4
Primary Antibodies

AB244788

Anti-IL-29 antibody [EPR19773-96] - BSA and Azide free (Capture)

RabMAb|Recombinant

Functional Studies (Neut/Block) - Anti-IL-29 antibody [EPR19773-96] - BSA and Azide free (Capture) (AB244788)

  • 0
  • 0
Primary Antibodies

AB233706

Anti-IL-6 antibody [EPR21711]

20ul selling size|RabMAb|Recombinant|KO Validated

Immunocytochemistry/ Immunofluorescence - Anti-IL-6 antibody [EPR21711] (AB233706)

  • 5
  • 1
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "FuncSNeutBlock" : {"fullname" : "Functional Studies (Neut/Block)", "shortname":"FuncS (Neut/Block)"}, "ELISPOT" : {"fullname" : "ELISPOT", "shortname":"ELISPOT"}, "IHCFr" : {"fullname" : "Immunohistochemistry (Frozen sections)", "shortname":"IHC-Fr"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>", "FuncSNeutBlock-species-checked": "guaranteed", "FuncSNeutBlock-species-dilution-info": "", "FuncSNeutBlock-species-notes": "<p></p>", "ELISPOT-species-checked": "guaranteed", "ELISPOT-species-dilution-info": "", "ELISPOT-species-notes": "<p></p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Ion exchange chromatography
Storage buffer
Constituents: PBS, 4.275% Trehalose
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils (PubMed : 2653458, PubMed : 9010276). Also acts on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation (By similarity). Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB (PubMed : 1495999, PubMed : 22528658). Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively (PubMed : 7613138).
See full target information IL5
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Publications (4)

Recent publications for all applications. Explore the full list and refine your search

Experimental dermatology 27:1328-1335 PubMed30230040

2018

Down-regulated SHARPIN may accelerate the development of atopic dermatitis through activating interleukin-33/ST2 signalling.

Applications

Unspecified application

Species

Unspecified reactive species

Lingjie Tang,Jiaman Wang,Jingna Zhu,Yanhua Liang

The Journal of allergy and clinical immunology 142:1489-1499.e23 PubMed30102935

2018

IgD-activated mast cells induce IgE synthesis in B cells in nasal polyps.

Applications

Unspecified application

Species

Unspecified reactive species

Guan-Ting Zhai,Hai Wang,Jing-Xian Li,Ping-Ping Cao,Wen-Xiu Jiang,Jia Song,Yin Yao,Zhi-Chao Wang,Zhe-Zheng Wang,Meng-Chen Wang,Bo Liao,Qi-Miao Feng,Xiang Lu,Heng Wang,Peisong Gao,Zheng Liu

International forum of allergy & rhinology 4:453-62 PubMed24504744

2014

Increase of high mobility group box chromosomal protein 1 in eosinophilic chronic rhinosinusitis with nasal polyps.

Applications

Unspecified application

Species

Unspecified reactive species

Daishi Chen,Mingfeng Mao,Luisa M Bellussi,Desiderio Passali,Lei Chen

Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale 32:386-92 PubMed23349558

2013

The role of High Mobility Group Box 1 chromosomal protein in the pathogenesis of chronic sinusitis and nasal polyposis.

Applications

IHC

Species

Unspecified reactive species

L M Bellussi,L Chen,D Chen,F M Passali,D Passali
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
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