AB233830

Anti-IL-9R antibody [1C2A6]

Name: Anti-IL-9R antibody [1C2A6] (ab233830) | Abcam
Brand: Abcam Limited
SKU: AB233830

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(1 Publication)

Mouse Monoclonal IL-9R antibody. Suitable for Flow Cyt, WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human IL9R aa 1-300.

View Alternative Names

CD129, Interleukin-9 receptor, IL-9 receptor, IL-9R, IL9R

3 Images

Flow Cytometry - Anti-IL-9R antibody [1C2A6] (AB233830)

Flow Cyt

Supplier Data

Flow Cytometry - Anti-IL-9R antibody [1C2A6] (AB233830)

Flow cytometric analysis of Ramos (Human Burkitt's lymphoma cell line) cells labeling IL9R using ab233830 at 1/200 dilution (green) compared with a negative control (red).

Supplier Data

Western blot - Anti-IL-9R antibody [1C2A6] (AB233830)

All lanes:

Western blot - Anti-IL-9R antibody [1C2A6] (ab233830) at 1/500 dilution

Lane 1:

HEK-293 (human epithelial cell line from embryonic kidney) cell lysate

Lane 2:

IL9R (aa: 41-270)-hIgGFc transfected HEK-293 cell lysate

Predicted band size: 57 kDa

false

Supplier Data

Western blot - Anti-IL-9R antibody [1C2A6] (AB233830)

Expected MW is 51.9

Lane 1:

Western blot - Anti-CHRND antibody [1H1F9] (<a href='/en-us/products/primary-antibodies/chrnd-antibody-1h1f9-ab233758'>ab233758</a>) at 1/500 dilution

Lane 1:

Western blot - Anti-IL-9R antibody [1C2A6] (ab233830) at 1/500 dilution

All lanes:

Recombinant human IL9R protein

Predicted band size: 57 kDa,59 kDa

true

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

1C2A6

Isotype

IgG1

Carrier free

Reacts with

Human

Applications

Flow Cyt, WB

applications

Immunogen

Recombinant Fragment Protein within Human IL9R aa 1-300. The exact immunogen used to generate this antibody is proprietary information.

Q01113

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1/200 - 1/400", "FlowCyt-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Purification notes

Purified from tissue culture supernatant.

Storage buffer

Preservative: 0.05% Sodium azide Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Interleukin 9 receptor (IL-9R) also known as CD129 is a transmembrane protein that belongs to the cytokine receptor family. It weighs approximately 54 kDa. IL-9R is expressed on various cell types including T cells B cells mast cells and certain epithelial cells. This receptor primarily binds to interleukin 9 (IL-9) and forms a heterodimer with the common gamma chain a component shared with other interleukin receptors.

Biological function summary

IL-9R plays essential roles in immune system signaling and regulation. As part of a receptor complex it activates downstream signaling pathways upon IL-9 binding influencing the immune responses such as cell survival proliferation and differentiation. IL-9R is also known to modulate allergic inflammation and has effects on both innate and adaptive immune responses.

Pathways

Research indicates that IL-9R is a participant in the JAK/STAT signaling pathway. This pathway includes janus kinase 1 (JAK1) and signal transducer and activator of transcription 5 (STAT5) both important for transmitting signals from IL-9 to exert cellular effects. IL-9R also connects to pathways involving other immune-modulating interleukins suggesting its broad role in immune regulation.

IL-9R holds a significant relationship with asthma and allergic diseases. It plays a role in promoting inflammatory responses in the airways related to conditions like asthma. Moreover IL-9R has connections with IL-13 in the context of allergic inflammation and this interaction may amplify disease pathology. Understanding the dynamics of IL-9R could offer insights into therapeutic targets for managing such immune-related disorders.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Plays an important role in the immune response against parasites by acting as a receptor of IL9.

See full target information IL9R

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Archives of medical science : AMS 20:1631-1654 PubMed39649262

2023

Oxymatrine inhibits the development of radioresistance in NSCLC cells by reversing EMT through the DcR3/AKT/GSK-3β pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Jianming Tang,Yu Cao,Hong Zhang,Rui Wang

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-IL-9R antibody [1C2A6]

Flow Cytometry - Anti-IL-9R antibody [1C2A6] (AB233830)

Western blot - Anti-IL-9R antibody [1C2A6] (AB233830)

Western blot - Anti-IL-9R antibody [1C2A6] (AB233830)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (1)

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