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AB128255

Anti-ILP3 antibody

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(1 Publication)

Rabbit Polyclonal INSL3 antibody. Suitable for ELISA, WB and reacts with Drosophila melanogaster samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Drosophila melanogaster Ilp3.

View Alternative Names

CG14167, Ilp3, Probable insulin-like peptide 3, dILP3, Insulin-related peptide 3

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Drosophila melanogaster

Applications

WB, ELISA

applications

Immunogen

Synthetic Peptide within Drosophila melanogaster Ilp3. The exact immunogen used to generate this antibody is proprietary information.

Q9VT52

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Drosophila melanogaster": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Lyophilized
Reconstitution
Reconstitute in 100 µL of water
Purification technique
Affinity purification Protein A
Storage buffer
Constituents: 2% Sucrose, 1.21% Tris, 0.75% Glycine
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Interleukin-Like Peptide 3 (ILP3) sometimes known as Insulin-Like Peptide 3 is a peptide hormone involved in metabolic regulation. ILP3 has a molecular mass of approximately 12 kDa. It is expressed mainly in the Leydig cells of the testes and ovaries. This expression pattern suggests a role in reproductive functions. ILP3 is also present in various other tissues indicating a wider range of physiological effects.
Biological function summary

ILP3 functions in growth and metabolic signaling. It does not form part of a larger protein complex but interacts with receptors like INSR and IGF1R. These interactions influence cellular proliferation and glucose metabolism. Its activities highlight important roles in maintaining metabolic homeostasis and reproductive processes affecting cell growth and differentiation.

Pathways

ILP3 is active in insulin signaling and growth factor pathways. It shares functional relationships with insulin receptor (INSR) and insulin-like growth factor 1 receptor (IGF1R). These pathways mediate important metabolic and growth processes aligning ILP3's function with that of other insulin-like peptides. Consequently ILP3 contributes to the regulation of key cellular activities concerning energy balance and growth.

ILP3 relates to metabolic syndrome and reproductive health issues. Its role in insulin signaling connects it to conditions like Type 2 diabetes. Altered ILP3 expression or function might contribute to these metabolic disorders. Furthermore its importance in reproductive processes links it with fertility-related conditions interacting with proteins such as IGF1 and INSR within these contexts.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information Ilp3
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Translational psychiatry 12:234 PubMed35668055

2022

Rare CACNA1H and RELN variants interact through mTORC1 pathway in oligogenic autism spectrum disorder.

Applications

Unspecified application

Species

Unspecified reactive species

André Luíz Teles E Silva,Talita Glaser,Karina Griesi-Oliveira,Juliana Corrêa-Velloso,Jaqueline Yu Ting Wang,Gabriele da Silva Campos,Henning Ulrich,Andrea Balan,Mehdi Zarrei,Edward J Higginbotham,Stephen W Scherer,Maria Rita Passos-Bueno,Andrea Laurato Sertié
View all publications
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