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AB97925

Anti-Influenza B virus Glycoprotein NB antibody

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(1 Publication)

Rabbit Polyclonal VNB antibody. Suitable for ELISA, WB, IHC-P and reacts with Influenza B samples. Cited in 1 publication.

View Alternative Names

Glycoprotein NB, NB

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Influenza B

Applications

ELISA, IHC-P, WB

applications

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Influenza B": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purity
Whole antiserum
Storage buffer
Constituents: Whole serum
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The Influenza B virus Glycoprotein NB also known as NB protein serves as a proton channel important for virus release and is about 27 kDa in mass. It is an integral membrane protein expressed on the surface of virions as well as on the infected cell membrane. NB forms homo-oligomers and is key for maintaining viral particle stability and facilitation of viral egress from host cells.
Biological function summary

This protein aids the virus by modulating the host cell's environment contributing to the virus's replication and spread. NB protein plays a part in ion balance disrupting host cell activities to favor viral replication. Within its function NB aligns with other viral components working together to enhance the virus's ability to sustain infection and evade the immune system.

Pathways

This protein significantly influences ion channel activity and viral replication processes. It interacts within the budding process pathways important for the release of viral particles from host cells. Interacting proteins include the viral neuraminidase and hemagglutinin which also facilitate these pathways ensuring efficient viral propagation.

The Glycoprotein NB plays a significant role in the pathology of seasonal Influenza B outbreaks. This pathology is linked with respiratory tract infections and can exacerbate conditions such as asthma. The NB protein associates with matrix protein 1 (M1) and other viral components contributing to the host’s responses during influenza infections. Understanding these interactions offers a pathway to develop therapeutic reagents targeting specific viral functions.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information Influenza B virus Glycoprotein NB
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Nature 603:131-137 PubMed35197628

2022

TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A.

Applications

Unspecified application

Species

Unspecified reactive species

Anna-Leigh Brown,Oscar G Wilkins,Matthew J Keuss,Sarah E Hill,Matteo Zanovello,Weaverly Colleen Lee,Alexander Bampton,Flora C Y Lee,Laura Masino,Yue A Qi,Sam Bryce-Smith,Ariana Gatt,Martina Hallegger,Delphine Fagegaltier,Hemali Phatnani,Jia Newcombe,Emil K Gustavsson,Sahba Seddighi,Joel F Reyes,Steven L Coon,Daniel Ramos,Giampietro Schiavo,Elizabeth M C Fisher,Towfique Raj,Maria Secrier,Tammaryn Lashley,Jernej Ule,Emanuele Buratti,Jack Humphrey,Michael E Ward,Pietro Fratta
View all publications
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Product promise

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