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AB103167

Anti-Inhibin beta E chain antibody

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Anti-Inhibin beta E chain antibody (ab103167) is a rabbit polyclonal antibody detecting Inhibin beta E chain in Western Blot. Suitable for Human, Mouse.

View Alternative Names

Inhibin beta E chain, Activin beta-E chain, INHBE

3 Images
Western blot - Anti-Inhibin beta E chain antibody (AB103167)
  • WB

Unknown

Western blot - Anti-Inhibin beta E chain antibody (AB103167)

All lanes:

Western blot - Anti-Inhibin beta E chain antibody (ab103167) at 1/500 dilution

All lanes:

Mouse liver tissue lysate at 50 µg

Predicted band size: 39 kDa

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Western blot - Anti-Inhibin beta E chain antibody (AB103167)
  • WB

Unknown

Western blot - Anti-Inhibin beta E chain antibody (AB103167)

All lanes:

Western blot - Anti-Inhibin beta E chain antibody (ab103167) at 1/500 dilution

All lanes:

Human liver tissue lysate at 50 µg

Predicted band size: 118 kDa,39 kDa,49 kDa,67 kDa

false

Western blot - Anti-Inhibin beta E chain antibody (AB103167)
  • WB

Unknown

Western blot - Anti-Inhibin beta E chain antibody (AB103167)

All lanes:

Western blot - Anti-Inhibin beta E chain antibody (ab103167) at 1/500 dilution

Lane 1:

INHBE transfected 293T cell line lysate at 25 µg

Lane 2:

Non-transfected 293T cell line lysate at 25 µg

Predicted band size: 23 kDa,29 kDa,31 kDa,32 kDa,33 kDa,39 kDa,41 kDa,43 kDa,48 kDa,59 kDa,60 kDa,69 kDa,96 kDa

Observed band size: 35 kDa,60 kDa

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Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Yes

Reacts with

Mouse, Human

Applications

WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human INHBE.

P58166

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500.00000 - 1/1000.00000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500.00000 - 1/1000.00000", "WB-species-notes": "<p></p>" } } }
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AB324257

Human INHBE ELISA Kit (Inhibin beta E)

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We recommend this product because it’s often used in the same experiment or related research.

We advise that you always check the datasheet to ensure it fits your experiments, or contact ourtechnical teamfor help.

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Product details

What is this antibody validated in?
Anti-Inhibin beta E chain antibody (ab103167) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB) in Human, Mouse samples.

What is the molecular weight of Inhibin beta E chain?
Anti-Inhibin beta E chain (ab103167) specifically detects a band for Inhibin beta E chain (UniProt: P58166) at a molecular weight of 39kDa.
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.4 Constituents: 100% PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The Inhibin beta E chain also known as 'INHBE' is a protein with multiple roles in the human body weighing about 42 kDa. It is a member of the transforming growth factor-beta (TGF-Β) superfamily. The protein can be expressed in many tissues including the liver and placenta. INHBE is associated with other proteins to form different complexes affecting various biological processes.
Biological function summary

The Inhibin beta E chain participates in the regulation of reproductive hormone activity. It forms either homodimers or heterodimers combining with other inhibin and activin molecules. The dimerization with alpha chains forms inhibins while pairing with other beta subunits forms activins. These complexes then modulate signaling pathways that adjust hormonal secretion particularly in the pituitary and gonadal tissues.

Pathways

Inhibin beta E chain plays a significant role in the activin signaling pathway. This pathway affects the regulation of FSH (follicle-stimulating hormone) secretion which is important for reproductive processes. INHBE relates to proteins such as follistatin and activin A within these pathways influencing activities flowing from ligand-receptor interactions to transcriptional regulation.

Inhibin beta E chain has been linked to certain reproductive and metabolic disorders. For instance abnormal expression or dysfunction of INHBE may relate to polycystic ovary syndrome (PCOS) affecting women’s fertility. Liver diseases such as non-alcoholic fatty liver disease (NAFLD) also show associations with INHBE levels. In these contexts INHBE interacts with various TGF-Β family proteins contributing to either disease progression or regulation.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
See full target information INHBE
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions
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