AB208035

Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95]

Name: Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (ab208035) | Abcam
Brand: Abcam Limited
SKU: AB208035
Price: 370 USD
Availability: InStock
Rating: 5 (1 reviews)

20ul selling size
RabMAb
Recombinant
What is this?

(1 Review)

(82 Publications)

Rabbit Recombinant Monoclonal JNK1 antibody. Suitable for IP, WB, ICC/IF, Flow Cyt (Intra) and reacts with Human, Mouse, Rat, Recombinant full length protein - Human samples. Cited in 82 publications.

View Alternative Names

JNK1, PRKM8, SAPK1, SAPK1C, MAPK8, Mitogen-activated protein kinase 8, MAP kinase 8, MAPK 8, JNK-46, Stress-activated protein kinase 1c, Stress-activated protein kinase JNK1, c-Jun N-terminal kinase 1, SAPK1c, JNK3, JNK3A, PRKM10, SAPK1B, MAPK10, Mitogen-activated protein kinase 10, MAP kinase 10, MAPK 10, MAP kinase p49 3F12, Stress-activated protein kinase 1b, Stress-activated protein kinase JNK3, c-Jun N-terminal kinase 3, SAPK1b, JNK2, PRKM9, SAPK1A, MAPK9, Mitogen-activated protein kinase 9, MAP kinase 9, MAPK 9, JNK-55, Stress-activated protein kinase 1a, Stress-activated protein kinase JNK2, c-Jun N-terminal kinase 2, SAPK1a

10 Images

Flow Cytometry (Intracellular) - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (AB208035)

Flow Cyt (Intra)

Supplier Data

Flow Cytometry (Intracellular) - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (AB208035)

Intracellular flow cytometric analysis of 4% paraformaldehyde-fixed Jurkat (Human T cell leukemia cell line from peripheral blood) cell linelabeling JNK1+JNK2+JNK3 with ab208035 at 1/100 dilution (red) compared with a Rabbit IgG, monoclonal [EPR25A] - Isotype Control (ab172730) (black) and an unlabelled control (cells without incubation with primary antibody and secondary antibody) (blue).

Goat anti-Rabbit IgG (Alexa Fluor^® 488) at 1/500 dilution was used as the secondary antibody.

Immunocytochemistry/ Immunofluorescence - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (AB208035)

ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (AB208035)

Immunofluorescent analysis of 4% paraformaldehyde-fixed, 0.1% Triton X-100 permeabilized HeLa (Human epithelial cell line from cervix adenocarcinoma) cell line labeling JNK1+JNK2+JNK3 with ab208035 at 1/1000 dilution, followed by Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077) secondary antibody at 1/1000 dilution (green).

Confocal image showing cytoplasm and weak nuclear staining on HeLa cell line.

The nuclear counterstain is DAPI (blue).

Tubulin is detected with Anti-alpha Tubulin antibody [DM1A] - Loading Control (ab7291) at 1/1000 dilution and Goat Anti-Mouse IgG H&L (Alexa Fluor® 594) preadsorbed (ab150120) at 1/1000 dilution (red).

The negative controls are as follows : -

-ve control 1 : ab208035 at 1/1000 dilution followed by ab150120 at 1/1000 dilution.

-ve control 2 : ab7291 at 1/1000 dilution followed by ab150077 at 1/1000 dilution.

Flow Cyt (Intra)

Supplier Data

Flow Cytometry (Intracellular) - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (AB208035)

Intracellular flow cytometric analysis of 4% paraformaldehyde-fixed HeLa (Human epithelial cell line from cervix adenocarcinoma) cell linelabeling JNK1+JNK2+JNK3with ab208035 at 1/100 dilution (red) compared with a Rabbit IgG, monoclonal [EPR25A] - Isotype Control (ab172730) (black) and an unlabelled control (cells without incubation with primary antibody and secondary antibody) (blue).

Goat anti-Rabbit IgG (Alexa Fluor^® 488) at 1/500 dilution was used as the secondary antibody.

Supplier Data

Immunoprecipitation - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (AB208035)

JNK1+JNK2+JNK3 was immunoprecipitated from 1mg of HeLa (Human epithelial cell line from cervix adenocarcinoma) whole cell lysate with ab208035 at 1/40 dilution.

Western blot was performed from the immunoprecipitate using ab208035 at 1/1000 dilution.

VeriBlot for IP Detection Reagent (HRP) (ab131366), was used for detection at 1/10000 dilution.

Lane 1 : HeLa whole cell lysate, 10ug (Input).

Lane 2 : ab208035 IP in HeLa whole cell lysate.

Lane 3 : Rabbit IgG, monoclonal [EPR25A] - Isotype Control (ab172730) instead of ab208035 in HeLa whole cell lysate.

Blocking and dilution buffer and concentration : 5% NFDM/TBST.

Exposure time : 10 seconds.

All lanes:

Immunoprecipitation - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (ab208035)

Predicted band size: 48 kDa

Observed band size: 46-54 kDa

false

ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (AB208035)

Immunofluorescent analysis of 4% paraformaldehyde-fixed, 0.1% Triton X-100 permeabilized NIH/3T3 (Mouse embryonic fibroblast cell line) cell line labeling JNK1+JNK2+JNK3 with ab208035 at 1/1000 dilution, followed by Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077) secondary antibody at 1/1000 dilution (green).

Confocal image showing cytoplasm and nuclear staining on NIH/3T3 cell line.

The nuclear counterstain is DAPI (blue).

The negative controls are as follows : -

-ve control 1 : ab208035 at 1/1000 dilution followed by ab150120 at 1/1000 dilution.

-ve control 2 : ab7291 at 1/1000 dilution followed by ab150077 at 1/1000 dilution.

Supplier Data

Western blot - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (AB208035)

Blocking/Dilution buffer : 5% NFDM/TBST.

All lanes:

Western blot - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (ab208035) at 1/2000 dilution

Lane 1:

Jurkat (Human T cell leukemia cell line from peripheral blood) whole cell lysate at 20 µg

Lane 2:

HeLa (Human epithelial cell line from cervix adenocarcinoma) whole cell lysate at 20 µg

Lane 3:

K562 (Human chronic myelogenous leukemia cell line from bone marrow) whole cell lysate at 20 µg

Lane 4:

MCF7 (Human breast adenocarcinoma cell line) whole cell lysate at 20 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/en-us/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/100000 dilution

Predicted band size: 48 kDa

Observed band size: 46-54 kDa

false

Exposure time: 3min

Supplier Data

Western blot - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (AB208035)

Blocking/Dilution buffer : 5% NFDM/TBST.

Exposure time : Lane 1 & 2 : 5 seconds; Lane 3 : 15 seconds.

Human JNK1 full length recombinant protein contains aa1-427 with a His-Tag®. Human JNK2 full length recombinant protein contains aa1-424 with a His-Tag®. Human JNK3 full length recombinant protein contains aa1-464 with a His-Tag®.

All three recombinant human full length proteins were made in-house.

All lanes:

Western blot - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (ab208035) at 1/2000 dilution

Lane 1:

Human JNK1 full length recombinant protein at 0.01 µg

Lane 2:

Human JNK2 full length recombinant protein at 0.01 µg

Lane 3:

Human JNK3 full length recombinant protein at 0.01 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/en-us/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/100000 dilution

Predicted band size: 48 kDa

false

Supplier Data

Western blot - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (AB208035)

Blocking/Dilution buffer : 5% NFDM/TBST.

All lanes:

Western blot - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (ab208035) at 1/2000 dilution

Lane 1:

Human fetal liver lysate at 10 µg

Lane 2:

Human fetal heart lysate at 10 µg

Lane 3:

Human fetal kidney lysate at 10 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG Peroxidase Conjugate, specific to the non-reduced form of IgG at 1/10000 dilution

Predicted band size: 48 kDa

Observed band size: 46-54 kDa

false

Exposure time: 30s

Supplier Data

Western blot - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (AB208035)

Blocking and Diluting buffer and concentration : 5% NFDM/TBST

All lanes:

Western blot - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (ab208035) at 1/2000 dilution

Lane 1:

C6 (Rat glial tumor cell line) whole cell lysate at 10 µg

Lane 2:

RAW 264.7 (Mouse macrophage cell line transformed with Abelson murine leukemia virus) whole cell lysate at 10 µg

Lane 3:

PC-12 (Rat adrenal gland pheochromocytoma cell line) whole cell lysate at 10 µg

Lane 4:

NIH/3T3 (Mouse embryonic fibroblast cell line) whole cell lysate at 10 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/en-us/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/100000 dilution

Predicted band size: 48 kDa

Observed band size: 46-54 kDa

false

Exposure time: 8s

Supplier Data

Western blot - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (AB208035)

Blocking/Dilution buffer : 5% NFDM/TBST.

Exposure time : Lane 1 : 4 seconds; Lane 2,3 & 4 : 30 seconds; Lane 5 : 15 seconds; Lane 6 & 7 : 3 minutes.

All lanes:

Western blot - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (ab208035) at 1/2000 dilution

Lane 1:

Mouse brain lysate at 10 µg

Lane 2:

Mouse heart lysate at 10 µg

Lane 3:

Mouse kidney lysate at 10 µg

Lane 4:

Mouse spleen lysate at 10 µg

Lane 5:

Rat brain lysate at 10 µg

Lane 6:

Rat kidney lysate at 10 µg

Lane 7:

Rat spleen lysate at 10 µg

Secondary

All lanes:

Western blot - Goat Anti-Rabbit IgG H&L (HRP) (<a href='/en-us/products/secondary-antibodies/goat-rabbit-igg-h-l-hrp-ab97051'>ab97051</a>) at 1/100000 dilution

Predicted band size: 48 kDa

Observed band size: 46-54 kDa

false

Carrier free

Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] - BSA and Azide free
Carrier free

Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] - BSA and Azide free (Detector)
519 Alexa Fluor® 488

Alexa Fluor® 488 Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95]
HRP

HRP Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95]

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR18841-95

Isotype

IgG

Carrier free

Reacts with

Mouse, Rat, Human

Applications

ICC/IF, IP, Flow Cyt (Intra), WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "FlowCytIntra" : {"fullname" : "Flow Cytometry (Intracellular)", "shortname":"Flow Cyt (Intra)"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "1/40", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000", "WB-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/1000", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "testedAndGuaranteed", "FlowCytIntra-species-dilution-info": "1/100", "FlowCytIntra-species-notes": "" }, "Mouse": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000", "WB-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/1000", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "guaranteed", "FlowCytIntra-species-dilution-info": "", "FlowCytIntra-species-notes": "" }, "Rat": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000", "WB-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "guaranteed", "FlowCytIntra-species-dilution-info": "", "FlowCytIntra-species-notes": "" }, "Recombinant full length protein - Human": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000", "WB-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "notRecommended", "FlowCytIntra-species-dilution-info": "", "FlowCytIntra-species-notes": "" } } }

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Product details

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

JNK1 JNK2 and JNK3 collectively known as c-Jun N-terminal kinases are important members of the mitogen-activated protein kinase (MAPK) family. JNK1 JNK2 and JNK3 have molecular weights of approximately 46 to 55 kDa with JNK1 being around 46 kDa JNK2 about 54 kDa and JNK3 also around 54 kDa. They are expressed differently across tissues: JNK1 and JNK2 are widely present in many tissues while JNK3 is mostly in brain heart and testis. These kinases primarily phosphorylate serine and threonine residues acting on various transcription factors including c-Jun to regulate cellular processes.

Biological function summary

These kinases function as significant regulators of cellular responses to stress and cytokines. They do not act alone but often form part of larger signaling complexes that include other MAPKs and various scaffold proteins. Their roles are substantial in cell differentiation proliferation apoptosis and migration. Precise regulation by JNK molecules influences these critical cellular events which play a role in maintaining homeostasis and response to external stresses.

Pathways

JNK proteins are central to the MAPK signaling pathway and are tightly linked to the MAPK/ERK pathway. Activation of the JNK pathways leads to the regulation of various other proteins including those in the apoptosis pathway such as Bcl-2 and Bax. These interactions focus on cellular stress response regulation and contribute to processes like inflammation stress-induced apoptosis and some metabolic processes.

JNKs have important roles in inflammatory diseases and neurodegenerative disorders such as Alzheimer's disease and Parkinson’s disease. Their activity links to the regulation of pro-inflammatory cytokines and neuronal apoptosis. JNK1 and JNK2 are particularly connected to inflammatory responses whereas JNK3 with its expression in the brain has associations with neuronal death in neurodegenerative diseases. Modulating JNK activity may offer therapeutic approaches for these conditions targeting pathways involving proteins like TNF-alpha and Aβ-amyloid.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracellular stimuli such as pro-inflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway (PubMed : 28943315). In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK8/JNK1. In turn, MAPK8/JNK1 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity (PubMed : 18307971). Phosphorylates the replication licensing factor CDT1, inhibiting the interaction between CDT1 and the histone H4 acetylase HBO1 to replication origins (PubMed : 21856198). Loss of this interaction abrogates the acetylation required for replication initiation (PubMed : 21856198). Promotes stressed cell apoptosis by phosphorylating key regulatory factors including p53/TP53 and Yes-associates protein YAP1 (PubMed : 21364637). In T-cells, MAPK8 and MAPK9 are required for polarized differentiation of T-helper cells into Th1 cells. Contributes to the survival of erythroid cells by phosphorylating the antagonist of cell death BAD upon EPO stimulation (PubMed : 21095239). Mediates starvation-induced BCL2 phosphorylation, BCL2 dissociation from BECN1, and thus activation of autophagy (PubMed : 18570871). Phosphorylates STMN2 and hence regulates microtubule dynamics, controlling neurite elongation in cortical neurons (By similarity). In the developing brain, through its cytoplasmic activity on STMN2, negatively regulates the rate of exit from multipolar stage and of radial migration from the ventricular zone (By similarity). Phosphorylates several other substrates including heat shock factor protein 4 (HSF4), the deacetylase SIRT1, ELK1, or the E3 ligase ITCH (PubMed : 16581800, PubMed : 17296730, PubMed : 20027304). Phosphorylates the CLOCK-BMAL1 heterodimer and plays a role in the regulation of the circadian clock (PubMed : 22441692). Phosphorylates the heat shock transcription factor HSF1, suppressing HSF1-induced transcriptional activity (PubMed : 10747973). Phosphorylates POU5F1, which results in the inhibition of POU5F1's transcriptional activity and enhances its proteasomal degradation (By similarity). Phosphorylates JUND and this phosphorylation is inhibited in the presence of MEN1 (PubMed : 22327296). In neurons, phosphorylates SYT4 which captures neuronal dense core vesicles at synapses (By similarity). Phosphorylates EIF4ENIF1/4-ET in response to oxidative stress, promoting P-body assembly (PubMed : 22966201). Phosphorylates SIRT6 in response to oxidative stress, stimulating its mono-ADP-ribosyltransferase activity (PubMed : 27568560). Phosphorylates NLRP3, promoting assembly of the NLRP3 inflammasome (PubMed : 28943315). Phosphorylates ALKBH5 in response to reactive oxygen species (ROS), promoting ALKBH5 sumoylation and inactivation (PubMed : 34048572).. JNK1 isoforms display different binding patterns : beta-1 preferentially binds to c-Jun, whereas alpha-1, alpha-2, and beta-2 have a similar low level of binding to both c-Jun or ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms.

See full target information MAPK8

Additional targets

MAPK9,MAPK10

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Publications (82)

Recent publications for all applications. Explore the full list and refine your search

Iranian journal of basic medical sciences 28:1220-1229 PubMed40809170

2025

Heat shock protein 90 mediates the protective effects of vericiguat on myocardial ischemia/reperfusion injury by inhibiting toll-like receptor 4 and c-Jun N-terminal kinases.

Applications

Unspecified application

Species

Unspecified reactive species

Si-Jie Pan,Jun-Yan Chen,Dong-Xiao Wang,Jian-Jun Meng,Min Wang,Guo-Qiang Zhong,Zhi-Yu Zeng,Rong-Hui Tu

Cell communication and signaling : CCS 22:160 PubMed38439009

2024

Pan-histone deacetylase inhibitor vorinostat suppresses osteoclastic bone resorption through modulation of RANKL-evoked signaling and ameliorates ovariectomy-induced bone loss.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaole Peng,Tianhao Wang,Qing Wang,Yuhu Zhao,Hao Xu,Huilin Yang,Ye Gu,Yunxia Tao,Bangsheng Yan,Yaozeng Xu,Dechun Geng

Shock (Augusta, Ga.) 60:400-409 PubMed37477381

2023

THE ALARMIN EFFECT OF HMGB1/RIP3 ON TRANSFUSION-RELATED ACUTE LUNG INJURY VIA TLR4/NF-ΚB OR MAPK PATHWAY.

Applications

Unspecified application

Species

Unspecified reactive species

Shuangchun Liu,Ronghai Lin,Xianchao Zhang,Yinyi Lv,Jie Zhu,Guang Chen,Yunting Du

Experimental and therapeutic medicine 25:260 PubMed37153901

2023

ADAM metallopeptidase domain 10 knockdown enables podocytes to resist high glucose stimulation by inhibiting pyroptosis via MAPK pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Chunjie Sui,Dan Zhou

Frontiers in pharmacology 14:1078205 PubMed36891270

2023

Dapagliflozin alleviates myocardial ischemia/reperfusion injury by reducing ferroptosis MAPK signaling inhibition.

Applications

Unspecified application

Species

Unspecified reactive species

Weixiang Chen,Yue Zhang,Zuoxiang Wang,Mingyue Tan,Jia Lin,Xiaodong Qian,Hongxia Li,Tingbo Jiang

International journal of chronic obstructive pulmonary disease 17:2589-2602 PubMed36267325

2022

IL-17A Promotes Epithelial ADAM9 Expression in Cigarette Smoke-Related COPD.

Applications

Unspecified application

Species

Unspecified reactive species

Danyang Li,Tong Wang,Qianli Ma,Lu Zhou,Yanqing Le,Yafei Rao,Liang Jin,Yuqiang Pei,Yaning Cheng,Chen Huang,Xiaoyan Gai,Yongchang Sun

Aging 14:5013-5022 PubMed35759577

2022

Huangqi Guizhi Wuwu Decoction can prevent and treat oxaliplatin-induced neuropathic pain by TNFα/IL-1β/IL-6/MAPK/NF-kB pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Mingzhu Li,Zheng Li,Xiande Ma,Shengbo Jin,Yang Cao,Xuebing Wang,Jian Zhao,Jianbo Wang,Xin Wang,Jian Xu

Journal of healthcare engineering 2022:9928546 PubMed35399826

2022

Qi Sui Zhu Shui Plaster Inhibits AQP1 and MAPK Signaling Reduces Liver Damage Induced by Cirrhotic Ascites.

Applications

Unspecified application

Species

Unspecified reactive species

Rong Zhen Zhang,Yin Liu,Min Li,Yong Lin Huang,Zhen Heng Song

Bioengineered 13:4869-4884 PubMed35196185

2022

MicroRNA miR-3646 promotes malignancy of lung adenocarcinoma cells by suppressing sorbin and SH3 domain-containing protein 1 via the c-Jun NH2-terminal kinase signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Chun Wang,Bo Cheng

Pharmaceutical biology 60:427-436 PubMed35175176

2022

Cyanidin attenuates the apoptosis of rat nucleus pulposus cells and the degeneration of intervertebral disc via the JAK2/STAT3 signal pathway and .

Applications

Unspecified application

Species

Unspecified reactive species

Xiaoliang Bai,Meichao Jiang,Jie Wang,Shuai Yang,Zhiwei Liu,Hongxin Zhang,Xiaojuan Zhu

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95]

Flow Cytometry (Intracellular) - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (AB208035)

Immunocytochemistry/ Immunofluorescence - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (AB208035)

Flow Cytometry (Intracellular) - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (AB208035)

Immunoprecipitation - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (AB208035)

Immunocytochemistry/ Immunofluorescence - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (AB208035)

Western blot - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (AB208035)

Western blot - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (AB208035)

Western blot - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (AB208035)

Western blot - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (AB208035)

Western blot - Anti-JNK1 + JNK2 + JNK3 antibody [EPR18841-95] (AB208035)

Related conjugates and formulations (4)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

Alternative Products

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Primary Antibodies

Primary Antibodies

Secondary Antibodies

Primary Antibodies

Reactivity data

Product details

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Additional targets

Publications (82)

Product promise