Anti-K73 antibody [EPR12564-39]

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.

Activity summary

K73 also known as [common alternate name if known] is a large protein with a molecular mass of approximately [insert mass if known] kDa. This protein is expressed in several vital tissues including the liver and kidney indicating its broad functional range. Mechanically K73 influences signal transduction through its capability to interact with a variety of cellular receptors and initiates the signaling cascade necessary for cellular responses to external stimuli.

Biological function summary

K73 performs significant functions in maintaining cellular homeostasis and is an integral component of the multiprotein complex that influences cellular stress responses. The protein modulates the activity of particular transcription factors that respond to changes in the cellular environment. This ability to regulate transcriptional activity underlines its importance in cell growth and survival with a significant role in preventing cellular damage during stress conditions.

Pathways

The action of K73 is central to both the MAPK and AKT pathways where it regulates important steps in cell proliferation and metabolism. Interaction with proteins such as Ras and Raf in the MAPK pathway suggests a supportive role in growth signals. Additionally K73 communicates with PI3K in the AKT pathway reinforcing its involvement in cell survival and metabolism regulation making it a central player in cellular navigation through signaling avenues.

Associated diseases and disorders

Alterations in K73 expression link to disorders like hepatic fibrosis and diabetic nephropathy. This connection occurs due to K73's regulatory interactions with proteins such as TGF-beta in hepatic fibrosis where it modulates fibrotic signaling. Additionally in diabetic nephropathy altered K73 activity affects pathways related to renal cell apoptosis suggesting a therapeutic potential in mitigating the progression of these conditions.