AB254906

Anti-KCNC1 antibody

Name: Anti-KCNC1 antibody (ab254906) | Abcam
Brand: Abcam Limited
SKU: AB254906
Price: 655 USD
Availability: InStock

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(1 Publication)

Rabbit Polyclonal KCNC1 antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human KCNC1 aa 100-200.

View Alternative Names

Voltage-gated potassium channel KCNC1, NGK2, Potassium voltage-gated channel subfamily C member 1, Voltage-gated potassium channel subunit Kv3.1, Voltage-gated potassium channel subunit Kv4, KCNC1

5 Images

Immunocytochemistry/ Immunofluorescence - Anti-KCNC1 antibody (AB254906)

ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-KCNC1 antibody (AB254906)

PFA fixed, Triton X-100 permeabilized U-2 OS (Human bone osteosarcoma epithelial cell line) cells labeling KCNC1 using ab254906 at 4µg/ml (green) in ICC/IF.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KCNC1 antibody (AB254906)

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KCNC1 antibody (AB254906)

Paraffin-embedded human cerebellum tissue stained for KCNC1 using ab254906 at 1/500 dilution in immunohistochemical analysis.

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KCNC1 antibody (AB254906)

Paraffin-embedded human kidney tissue stained for KCNC1 using ab254906 at 1/500 dilution in immunohistochemical analysis. No positivity in cells in tubules as expected.

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KCNC1 antibody (AB254906)

Paraffin-embedded human small intestine tissue stained for KCNC1 using ab254906 at 1/500 dilution in immunohistochemical analysis. No positivity in glandular cells as expected.

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KCNC1 antibody (AB254906)

Paraffin-embedded human cerebral cortex tissue stained for KCNC1 using ab254906 at 1/500 dilution in immunohistochemical analysis.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

IHC-P, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human KCNC1 aa 100-200. The exact immunogen used to generate this antibody is proprietary information.

P48547

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/500 - 1/1000", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p>Fixation/Permeabilization: PFA/Triton X-100.</p>" }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Voltage-gated potassium channel that opens in response to the voltage difference across the membrane and through which potassium ions pass in accordance with their electrochemical gradient (PubMed : 25401298, PubMed : 35840580). The mechanism is time-dependent and inactivation is slow (By similarity). Plays an important role in the rapid repolarization of fast-firing brain neurons (By similarity). Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNC2, and possibly other family members as well (By similarity). Contributes to fire sustained trains of very brief action potentials at high frequency in pallidal neurons (By similarity).

See full target information KCNC1

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Oncology letters 22:532 PubMed34079591

2021

miR-590-5p targets RMND5A and promotes migration in pancreatic adenocarcinoma cell lines.

Applications

Unspecified application

Species

Unspecified reactive species

Sixing Chen,Yu Chen,Yao Wen,Wanwan Cai,Ping Zhu,Wuzhou Yuan,Yongqing Li,Xiongwei Fan,Yongqi Wan,Fang Li,Jian Zhuang,Zhigang Jiang,Xiushan Wu,Yuequn Wang

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-KCNC1 antibody

Immunocytochemistry/ Immunofluorescence - Anti-KCNC1 antibody (AB254906)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KCNC1 antibody (AB254906)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KCNC1 antibody (AB254906)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KCNC1 antibody (AB254906)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KCNC1 antibody (AB254906)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (1)

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