JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB65795

Anti-KCNE1 antibody

Be the first to review this product! Submit a review

|

(3 Publications)

Rabbit Polyclonal KCNE1 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Synthetic Peptide within Human Potassium voltage-gated channel subfamily E member 1.

View Alternative Names

Potassium voltage-gated channel subfamily E member 1, Delayed rectifier potassium channel subunit IsK, IKs producing slow voltage-gated potassium channel subunit beta Mink, Minimal potassium channel, MinK, KCNE1

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF, WB, IHC-P

applications

Immunogen

Synthetic Peptide within Human Potassium voltage-gated channel subfamily E member 1. The exact immunogen used to generate this antibody is proprietary information.

P15382

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purity
Whole antiserum
Storage buffer
Constituents: Whole serum
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

Ancillary protein that functions as a regulatory subunit of the voltage-gated potassium (Kv) channel complex composed of pore-forming and potassium-conducting alpha subunits and of regulatory beta subunits. KCNE1 beta subunit modulates the gating kinetics and enhances stability of the channel complex (PubMed : 19219384, PubMed : 20533308, PubMed : 9230439). Alters the gating of the delayed rectifier Kv channel containing KCNB1 alpha subunit (PubMed : 19219384). Associates with KCNQ1/KVLQT1 alpha subunit to form the slowly activating delayed rectifier cardiac potassium (IKs) channel responsible for ventricular muscle action potential repolarization (PubMed : 20533308). The outward current reaches its steady state only after 50 seconds (Probable). Assembly with KCNH2/HERG alpha subunit Kv channel may regulate the rapidly activating component of the delayed rectifying potassium current (IKr) in heart (PubMed : 9230439).
See full target information Potassium voltage-gated channel subfamily E member 1
style
left-column

Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in physiology 12:761910 PubMed34744797

2021

KCNQ1 Potassium Channel Expressed in Human Sperm Is Involved in Sperm Motility, Acrosome Reaction, Protein Tyrosine Phosphorylation, and Ion Homeostasis During Capacitation.

Applications

Unspecified application

Species

Unspecified reactive species

Tian Gao,Kun Li,Fei Liang,Jianmin Yu,Ajuan Liu,Ya Ni,Peibei Sun

PloS one 13:e0190698 PubMed29470513

2018

Offspring sex impacts DNA methylation and gene expression in placentae from women with diabetes during pregnancy.

Applications

Unspecified application

Species

Unspecified reactive species

Jacqueline Alexander,April M Teague,Jing Chen,Christopher E Aston,Yuet-Kin Leung,Steven Chernausek,Rebecca A Simmons,Sara E Pinney

British journal of pharmacology 173:2046-61 PubMed27076034

2016

A novel transgenic rabbit model with reduced repolarization reserve: long QT syndrome caused by a dominant-negative mutation of the KCNE1 gene.

Applications

Unspecified application

Species

Unspecified reactive species

Péter Major,István Baczkó,László Hiripi,Katja E Odening,Viktor Juhász,Zsófia Kohajda,András Horváth,György Seprényi,Mária Kovács,László Virág,Norbert Jost,János Prorok,Balázs Ördög,Zoltán Doleschall,Stanley Nattel,András Varró,Zsuzsanna Bősze
View all publications
style
left-column
style
left-column
style
right-column

Alternative Products

Primary Antibodies

AB180843

Anti-KCNE1 antibody

Western blot - Anti-KCNE1 antibody (AB180843)

  • 0
  • 0

Complementary Products

Primary Antibodies

AB76818

Anti-IFIT3/P60 antibody

Western blot - Anti-IFIT3/P60 antibody (AB76818)

  • 0
  • 0
Primary Antibodies

AB305231

Anti-IFIT2 antibody [EPR26404-119]

BOND RX™ Validated|20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IFIT2 antibody [EPR26404-119] (AB305231)

  • 0
  • 0
Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Flow Cytometry - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

  • 5
  • 20
Primary Antibodies

AB84819

Anti-KCNQ1 antibody [N37A/10]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KCNQ1 antibody [N37A/10] (AB84819)

  • 0
  • 0

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com