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AB198043

Anti-KCNK17 antibody - N-terminal

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(2 Publications)

Rabbit Polyclonal KCNK17 antibody. N-terminal. Suitable for WB, IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human KCNK17.

View Alternative Names

TALK2, TASK4, UNQ5816/PRO19634, KCNK17, Potassium channel subfamily K member 17, 2P domain potassium channel Talk-2, Acid-sensitive potassium channel protein TASK-4, TWIK-related acid-sensitive K(+) channel 4, TWIK-related alkaline pH-activated K(+) channel 2, TALK-2

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KCNK17 antibody - N-terminal (AB198043)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KCNK17 antibody - N-terminal (AB198043)

Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue labeling KCNK17 with ab198043 at 1/60 dilution.

Western blot - Anti-KCNK17 antibody - N-terminal (AB198043)
  • WB

Supplier Data

Western blot - Anti-KCNK17 antibody - N-terminal (AB198043)

8% SDS-PAGE

All lanes:

Western blot - Anti-KCNK17 antibody - N-terminal (ab198043) at 1/300 dilution

All lanes:

LO2 cell lysate at 40 µg

Predicted band size: 37 kDa

false

Exposure time: 10s

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Human KCNK17. The exact immunogen used to generate this antibody is proprietary information.

Q96T54

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/300 - 1/2000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/60 - 1/300", "IHCP-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.4 Preservative: 0.05% Sodium azide Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

K(+) channel that conducts voltage-dependent outward rectifying currents upon membrane depolarization. Voltage sensing is coupled to K(+) electrochemical gradient in an 'ion flux gating' mode where outward but not inward ion flow opens the gate (PubMed : 11248242, PubMed : 11263999, PubMed : 26919430, PubMed : 36063992). Homo- and heterodimerizes to form functional channels with distinct regulatory and gating properties (PubMed : 36063992). Present in the cardiac conduction system where it may regulate action potential duration and beating frequency of cardiac myocytes (PubMed : 24972929). Permeable to other monovalent cations such as Rb(+) and Cs(+) (By similarity) (PubMed : 26919430).
See full target information KCNK17
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Molecular biology of the cell 30:1425-1436 PubMed30969900

2019

N-glycosylation-dependent regulation of hK17.1 currents.

Applications

Unspecified application

Species

Unspecified reactive species

Felix Wiedmann,Daniel Schlund,Niels Voigt,Antonius Ratte,Manuel Kraft,Hugo A Katus,Constanze Schmidt

Naunyn-Schmiedeberg's archives of pharmacology 391:1119-1131 PubMed30008082

2018

Cardiovascular pharmacology of K17.1 (TASK-4, TALK-2) two-pore-domain K channels.

Applications

Unspecified application

Species

Unspecified reactive species

Ingo Staudacher,Claudius Illg,Sam Chai,Isabelle Deschenes,Sebastian Seehausen,Dominik Gramlich,Mara Elena Müller,Teresa Wieder,Ann-Kathrin Rahm,Christina Mayer,Patrick A Schweizer,Hugo A Katus,Dierk Thomas
View all publications
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