AB105392

Anti-KIAA0652/ATG13 antibody

Name: Anti-KIAA0652/ATG13 antibody (ab105392) | Abcam
Brand: Abcam Limited
SKU: AB105392
Rating: 4 (1 reviews)

(1 Review)

(8 Publications)

Rabbit Polyclonal KIAA0652/ATG13 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Rat, Mouse, Human samples. Cited in 8 publications. Immunogen corresponding to Synthetic Peptide within Human ATG13.

View Alternative Names

KIAA0652, ATG13, Autophagy-related protein 13

1 Images

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Western blot - Anti-KIAA0652/ATG13 antibody (AB105392)

All lanes:

Western blot - Anti-KIAA0652/ATG13 antibody (ab105392) at 1 µg/mL

Lane 1:

Rat heart tissue lysate without blocking peptide at 15 µg

Lane 2:

Rat heart tissue lysate with blocking peptide at 15 µg

Predicted band size: 56 kDa

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Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Rat, Mouse, Human

Applications

IHC-P, WB, ICC/IF

applications

Immunogen

Synthetic Peptide within Human ATG13. The exact immunogen used to generate this antibody is proprietary information.

O75143

Specificity

ab105392 is predicted to not cross-react with other ATG members. Two isoforms of KIAA0652/ATG13 are known to exist; this antibody will recognize both isoforms.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Mouse": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1-2 µg/mL", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.

See full target information ATG13

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Publications (8)

Recent publications for all applications. Explore the full list and refine your search

Autophagy 19:3079-3095 PubMed37464898

2023

Aging Differentially Affects Axonal Autophagosome Formation and Maturation.

Applications

Unspecified application

Species

Unspecified reactive species

Heather Tsong,Erika Lf Holzbaur,Andrea Kh Stavoe

Frontiers in oncology 12:937209 PubMed36313671

2022

CircHADHA-augmented autophagy suppresses tumor growth of colon cancer by regulating autophagy-related gene miR-361.

Applications

Unspecified application

Species

Unspecified reactive species

Ying Shi,Jinying Li,Ming Tang,Jingwen Liu,Yalu Zhong,Wei Huang

Molecular medicine reports 23: PubMed33846806

2021

miR‑654‑5p inhibits autophagy by targeting ATG7 via mTOR signaling in intervertebral disc degeneration.

Applications

Unspecified application

Species

Unspecified reactive species

Shanzheng Wang,Yudong Guo,Xuejun Zhang,Chen Wang

eLife 8: PubMed31309927

2019

Expression of WIPI2B counteracts age-related decline in autophagosome biogenesis in neurons.

Applications

Unspecified application

Species

Unspecified reactive species

Andrea Kh Stavoe,Pallavi P Gopal,Andrea Gubas,Sharon A Tooze,Erika Lf Holzbaur

Frontiers in pharmacology 10:603 PubMed31214032

2019

Shen-Yuan-Dan Capsule Attenuates Atherosclerosis and Foam Cell Formation by Enhancing Autophagy and Inhibiting the PI3K/Akt/mTORC1 Signaling Pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Mingxue Zhou,Pan Ren,Ying Zhang,Sinai Li,Mengjie Li,Ping Li,Juju Shang,Weihong Liu,Hongxu Liu

Autophagy 15:1495-1505 PubMed30821607

2019

Down-regulated TMED10 in Alzheimer disease induces autophagy via ATG4B activation.

Applications

Unspecified application

Species

Unspecified reactive species

Ji Hyun Shin,So Jung Park,Doo Sin Jo,Na Yeon Park,Joon Bum Kim,Ji-Eun Bae,Yoon Kyung Jo,Jung Jin Hwang,Jin-A Lee,Dong-Gyu Jo,Jin Cheon Kim,Yong Keun Jung,Jae-Young Koh,Dong-Hyung Cho

International journal of molecular medicine 37:309-18 PubMed26647915

2015

Electroacupuncture protects against ischemic stroke by reducing autophagosome formation and inhibiting autophagy through the mTORC1-ULK1 complex-Beclin1 pathway.

Applications

Species

Unspecified reactive species

Weilin Liu,Guanhao Shang,Shanli Yang,Jia Huang,Xiehua Xue,Yunjiao Lin,Yi Zheng,Xian Wang,Lulu Wang,Ruhui Lin,Jing Tao,Lidian Chen

Cancer research 72:230-8 PubMed22102692

2011

HMGB1 promotes drug resistance in osteosarcoma.

Applications

Species

Human

Jun Huang,Jiangdong Ni,Ke Liu,Yan Yu,Min Xie,Rui Kang,Philip Vernon,Lizhi Cao,Daolin Tang

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-KIAA0652/ATG13 antibody

Western blot - Anti-KIAA0652/ATG13 antibody (AB105392)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Specificity

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Product protocols

Target data

Publications (8)

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