Rabbit Polyclonal KIAA0652/ATG13 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Rat, Mouse, Human samples. Cited in 7 publications. Immunogen corresponding to Synthetic Peptide within Human ATG13.
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Publications
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- Frontiers in oncology 12:9372092022CircHADHA-augmented autophagy suppresses tumor growth of colon cancer by regulating autophagy-related gene miR-361.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYing Shi,Jinying Li,Ming Tang,Jingwen Liu,Yalu Zhong,Wei HuangPubMed 36313671
- Molecular medicine reports 23:2021miR‑654‑5p inhibits autophagy by targeting ATG7 via mTOR signaling in intervertebral disc degeneration.Applications:Unspecified applicationReactive species:Unspecified reactive speciesShanzheng Wang,Yudong Guo,Xuejun Zhang,Chen WangPubMed 33846806
- eLife 8:2019Expression of WIPI2B counteracts age-related decline in autophagosome biogenesis in neurons.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAndrea Kh Stavoe et. al.PubMed 31309927
- Frontiers in pharmacology 10:6032019Shen-Yuan-Dan Capsule Attenuates Atherosclerosis and Foam Cell Formation by Enhancing Autophagy and Inhibiting the PI3K/Akt/mTORC1 Signaling Pathway.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMingxue Zhou et. al.PubMed 31214032
- Autophagy 15:1495-15052019Down-regulated TMED10 in Alzheimer disease induces autophagy via ATG4B activation.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJi Hyun Shin et. al.PubMed 30821607
- International journal of molecular medicine 37:309-182015Electroacupuncture protects against ischemic stroke by reducing autophagosome formation and inhibiting autophagy through the mTORC1-ULK1 complex-Beclin1 pathway.Applications:WBReactive species:Unspecified reactive speciesWeilin Liu,Guanhao Shang,Shanli Yang,Jia Huang,Xiehua Xue,Yunjiao Lin,Yi Zheng,Xian Wang,Lulu Wang,Ruhui Lin,Jing Tao,Lidian ChenPubMed 26647915
- Cancer research 72:230-82011HMGB1 promotes drug resistance in osteosarcoma.Applications:WBReactive species:HumanJun Huang,Jiangdong Ni,Ke Liu,Yan Yu,Min Xie,Rui Kang,Philip Vernon,Lizhi Cao,Daolin TangPubMed 22102692
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: PBS- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Synthetic Peptide within Human ATG13. The exact immunogen used to generate this antibody is proprietary information. Database link O75143
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Reactivity data
Select an application| WB | IHC-P | ICC/IF | |
|---|---|---|---|
| Human | Predicted | Expected | Predicted |
| Mouse | Expected | Expected | Tested |
| Rat | Tested | Expected | Expected |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Rat | Dilution info 1-2 µg/mL | Notes - |
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info Use at an assay dependent concentration. | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info - | Notes - |
IHC-P
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Rat, Human | Dilution info Use at an assay dependent concentration. | Notes - |
ICC/IF
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info - | Notes - |
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Rat | Dilution info Use at an assay dependent concentration. | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info - | Notes - |
Target data
Function
Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
Alternative names
KIAA0652, ATG13, Autophagy-related protein 13
Recommended products
Rabbit Polyclonal KIAA0652/ATG13 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Rat, Mouse, Human samples. Cited in 7 publications. Immunogen corresponding to Synthetic Peptide within Human ATG13.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: PBS- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Synthetic Peptide within Human ATG13. The exact immunogen used to generate this antibody is proprietary information. Database link O75143
- Purification technique
- Affinity purification Immunogen
- Specificity
ab105392 is predicted to not cross-react with other ATG members. Two isoforms of KIAA0652/ATG13 are known to exist; this antibody will recognize both isoforms.
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
Western blot - Anti-KIAA0652/ATG13 antibody (ab105392)
All lanes: Western blot - Anti-KIAA0652/ATG13 antibody (ab105392) at 1 µg/mL
Lane 1: Rat heart tissue lysate without blocking peptide at 15 µg
Lane 2: Rat heart tissue lysate with blocking peptide at 15 µg
Predicted band size: 56 kDa
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