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AB150966

Anti-KIF26A antibody

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(2 Publications)

Rabbit Polyclonal KIF26A antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human KIF26A aa 950-1050.

View Alternative Names

KIAA1236, KIF26A, Kinesin-like protein KIF26A

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KIF26A antibody (AB150966)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KIF26A antibody (AB150966)

Immunohistochemical analysis of paraffin-embedded Human adrenal gland tissue labelling KIF26A with ab150966 at 1/500 dilution.

Immunocytochemistry/ Immunofluorescence - Anti-KIF26A antibody (AB150966)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-KIF26A antibody (AB150966)

Immunofluorescent staining of Human cell line A-431 shows positivity in plasma membrane. Recommended concentration of ab150966 1-4 µg/ml. Cells treated with PFA/Triton X-100.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human KIF26A aa 950-1050. The exact immunogen used to generate this antibody is proprietary information.

Q9ULI4

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/500 - 1/1000", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p></p>" } } }
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Product details

The antibody solution should be gently mixed before use.
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Atypical kinesin that plays a key role in enteric neuron development. Acts by repressing a cell growth signaling pathway in the enteric nervous system development, possibly via its interaction with GRB2 that prevents GRB2-binding to SHC, thereby attenating the GDNF-Ret signaling (By similarity). Binds to microtubules but lacks microtubule-based motility due to the absence of ATPase activity (By similarity). Plays a critical role in cerebral cortical development. It probably acts as a microtubule stabilizer that regulates neurite growth and radial migration of cortical excitatory neurons (PubMed : 36228617).
See full target information KIF26A
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in oncology 10:530933 PubMed33505901

2021

E2F1 Induces KIF26A Transcription and Promotes Cell Cycle Progression CDK-RB-E2Fs Feedback Loop in Breast Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Jing Xu,Lei Liu,Ranran Ma,Yawen Wang,Xu Chen,Haiting Liu,Youxin Ji,Tiantian Liu,Peng Gao

Disease models & mechanisms : PubMed33318051

2020

Hearing impairment due to mutations suggests both loss and gain of function effects.

Applications

Unspecified application

Species

Unspecified reactive species

Morag A Lewis,Francesca Di Domenico,Neil J Ingham,Haydn M Prosser,Karen P Steel
View all publications
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