Rabbit Polyclonal KIF3A antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Mouse, Rat, Human, Cow samples. Cited in 43 publications. Immunogen corresponding to Synthetic Peptide within Mouse Kif3a aa 650 to C-terminus conjugated to Keyhole Limpet Haemocyanin.
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Publications
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- Journal of the American Society of Nephrology : JASN 33:1726-17412022KLC3 Regulates Ciliary Trafficking and Cyst Progression in CILK1 Deficiency-Related Polycystic Kidney Disease.Applications:Unspecified applicationReactive species:Unspecified reactive speciesGyuyeong Rah,Hwayeon Cha,Joohee Kim,Jieun Song,Hyunho Kim,Yun Kyu Oh,Curie Ahn,Minyong Kang,Jongmin Kim,Kyung Hyun Yoo,Min Jung Kim,Hyuk Wan Ko,Je Yeong Ko,Jong Hoon ParkPubMed 35961787
- Nature biomedical engineering 6:463-4752022Modelling ciliopathy phenotypes in human tissues derived from pluripotent stem cells with genetically ablated cilia.Applications:Unspecified applicationReactive species:Unspecified reactive speciesNelly M Cruz,Raghava Reddy,José L McFaline-Figueroa,Christine Tran,Hongxia Fu,Benjamin S FreedmanPubMed 35478224
- Matrix biology : journal of the International Society for Matrix Biology 107:1-232022Coordination of two kinesin superfamily motor proteins, KIF3A and KIF13A, is essential for pericellular matrix degradation by membrane-type 1 matrix metalloproteinase (MT1-MMP) in cancer cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesValentina Gifford,Anna Woskowicz,Noriko Ito,Stefan Balint,B Christopher Lagerholm,Michael L Dustin,Yoshifumi ItohPubMed 35122963
- International journal of molecular sciences 22:2021Photoreceptor Compartment-Specific TULP1 Interactomes.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLindsey A Ebke,Satyabrata Sinha,Gayle J T Pauer,Stephanie A HagstromPubMed 34360830
- Cell reports 36:1093692021Molecular motor protein KIF5C mediates structural plasticity and long-term memory by constraining local translation.Applications:Unspecified applicationReactive species:Unspecified reactive speciesSupriya Swarnkar,Yosef Avchalumov,Isabel Espadas,Eddie Grinman,Xin-An Liu,Bindu L Raveendra,Aya Zucca,Sonia Mediouni,Abhishek Sadhu,Susana Valente,Damon Page,Kyle Miller,Sathyanarayanan V PuthanveettilPubMed 34260917
- The Journal of cell biology 220:2021Small noncoding vault RNA modulates synapse formation by amplifying MAPK signaling.Applications:Unspecified applicationReactive species:Unspecified reactive speciesShuji Wakatsuki,Yoko Takahashi,Megumi Shibata,Naoki Adachi,Tadahiro Numakawa,Hiroshi Kunugi,Toshiyuki ArakiPubMed 33439240
- Glia 69:1184-12032020Kif3a deletion prevents primary cilia assembly on oligodendrocyte progenitor cells, reduces oligodendrogenesis and impairs fine motor function.Applications:Unspecified applicationReactive species:Unspecified reactive speciesCarlie L Cullen,Megan O'Rourke,Shannon J Beasley,Loic Auderset,Yilan Zhen,Renee E Pepper,Robert Gasperini,Kaylene M YoungPubMed 33368703
- eLife 9:2020Functional exploration of heterotrimeric kinesin-II in IFT and ciliary length control in .Applications:Unspecified applicationReactive species:Unspecified reactive speciesShufen Li et. al.PubMed 33112235
- EMBO molecular medicine 12:e117392020Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMichaela Bosakova et. al.PubMed 33200460
- Oncology letters 20:3482020Kinesin family member 3A inhibits the carcinogenesis of non-small cell lung cancer and prolongs survival.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYie Yang et. al.PubMed 33123259
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.097% Sodium azide
Constituents: 0.0268% PBS- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Synthetic Peptide within Mouse Kif3a aa 650 to C-terminus conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information. Database link P28741
Reactivity data
Select an application| WB | IHC-P | ICC/IF | |
|---|---|---|---|
| Human | Expected | Predicted | Expected |
| Mouse | Expected | Tested | Expected |
| Rat | Expected | Tested | Expected |
| Cow | Expected | Predicted | Expected |
WB
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info - | Notes This concentration is determined by blotting using a rat brain homogenate and a whole cell extract of rat pheochromocytoma PC12 cell line. Staining of KIF3A is specifically inhibited by the KIF3A immunizing peptide. |
Species Rat | Dilution info - | Notes This concentration is determined by blotting using a rat brain homogenate and a whole cell extract of rat pheochromocytoma PC12 cell line. Staining of KIF3A is specifically inhibited by the KIF3A immunizing peptide. |
Species Human | Dilution info - | Notes This concentration is determined by blotting using a rat brain homogenate and a whole cell extract of rat pheochromocytoma PC12 cell line. Staining of KIF3A is specifically inhibited by the KIF3A immunizing peptide. |
Species Cow | Dilution info - | Notes This concentration is determined by blotting using a rat brain homogenate and a whole cell extract of rat pheochromocytoma PC12 cell line. Staining of KIF3A is specifically inhibited by the KIF3A immunizing peptide. |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info 1/100 | Notes - |
Species Rat | Dilution info 1/100 | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Cow, Human | Dilution info - | Notes - |
ICC/IF
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Rat, Human, Cow | Dilution info Use at an assay dependent concentration. | Notes - |
Associated Products
Select an associated product type
2 products for Alternative Product
Target data
Function
Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation. Plays a role in centriole cohesion and subdistal appendage organization and function. Regulates the formation of the subdistal appendage via recruitment of DCTN1 to the centriole. Also required for ciliary basal feet formation and microtubule anchoring to mother centriole.
Alternative names
KIF3, KIF3A, Kinesin-like protein KIF3A, Microtubule plus end-directed kinesin motor 3A
Recommended products
Rabbit Polyclonal KIF3A antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Mouse, Rat, Human, Cow samples. Cited in 43 publications. Immunogen corresponding to Synthetic Peptide within Mouse Kif3a aa 650 to C-terminus conjugated to Keyhole Limpet Haemocyanin.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.097% Sodium azide
Constituents: 0.0268% PBS- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Synthetic Peptide within Mouse Kif3a aa 650 to C-terminus conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information. Database link P28741
- Purity
- IgG fraction
- Concentration
- Purification notes
Whole antiserum is fractionated and then further purified by ion-exchange chromatography to provide the IgG fraction of antiserum that is essentially free of other rabbit serum proteins.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Storage in frost-free freezers is not recommended.
If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
4 product images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KIF3A antibody (ab11259)
Paraffin-embedded rat brain tissue stained for KIF3A with ab11259 at 0.1 μg/mL in immunohistochemical analysis.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KIF3A antibody (ab11259)
Paraffin-embedded rat brain tissue stained for KIF3A with ab11259 at 0.1 μg/mL in immunohistochemical analysis.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KIF3A antibody (ab11259)
Paraffin-embedded mouse brain tissue stained for KIF3A with ab11259 at 0.4 μg/mL in immunohistochemical analysis.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KIF3A antibody (ab11259)
Paraffin-embedded mouse brain tissue stained for KIF3A with ab11259 at 0.4 μg/mL in immunohistochemical analysis.
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