JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB11259

Anti-KIF3A antibody

5

(11 Reviews)

|

(48 Publications)

Rabbit Polyclonal KIF3A antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Mouse, Rat, Human, Cow samples. Cited in 48 publications. Immunogen corresponding to Synthetic Peptide within Mouse Kif3a aa 650 to C-terminus conjugated to Keyhole Limpet Haemocyanin.

View Alternative Names

KIF3, KIF3A, Kinesin-like protein KIF3A, Microtubule plus end-directed kinesin motor 3A

4 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KIF3A antibody (AB11259)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KIF3A antibody (AB11259)

Paraffin-embedded mouse brain tissue stained for KIF3A with ab11259 at 0.4 μg/mL in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KIF3A antibody (AB11259)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KIF3A antibody (AB11259)

Paraffin-embedded mouse brain tissue stained for KIF3A with ab11259 at 0.4 μg/mL in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KIF3A antibody (AB11259)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KIF3A antibody (AB11259)

Paraffin-embedded rat brain tissue stained for KIF3A with ab11259 at 0.1 μg/mL in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KIF3A antibody (AB11259)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-KIF3A antibody (AB11259)

Paraffin-embedded rat brain tissue stained for KIF3A with ab11259 at 0.1 μg/mL in immunohistochemical analysis.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Rat, Cow, Human

Applications

IHC-P, WB, ICC/IF

applications

Immunogen

Synthetic Peptide within Mouse Kif3a aa 650 to C-terminus conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.

P28741

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p>This concentration is determined by blotting using a rat brain homogenate and a whole cell extract of rat pheochromocytoma PC12 cell line. Staining of KIF3A is specifically inhibited by the KIF3A immunizing peptide.</p>", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p>This concentration is determined by blotting using a rat brain homogenate and a whole cell extract of rat pheochromocytoma PC12 cell line. Staining of KIF3A is specifically inhibited by the KIF3A immunizing peptide.</p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p>This concentration is determined by blotting using a rat brain homogenate and a whole cell extract of rat pheochromocytoma PC12 cell line. Staining of KIF3A is specifically inhibited by the KIF3A immunizing peptide.</p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" }, "Cow": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p>This concentration is determined by blotting using a rat brain homogenate and a whole cell extract of rat pheochromocytoma PC12 cell line. Staining of KIF3A is specifically inhibited by the KIF3A immunizing peptide.</p>", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" } } }

Product details

Storage in frost-free freezers is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.

Properties and storage information

Form
Liquid
Purity
IgG fraction
Purification notes
Whole antiserum is fractionated and then further purified by ion-exchange chromatography to provide the IgG fraction of antiserum that is essentially free of other rabbit serum proteins.
Storage buffer
pH: 7.4 Preservative: 0.097% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation. Plays a role in centriole cohesion and subdistal appendage organization and function. Regulates the formation of the subdistal appendage via recruitment of DCTN1 to the centriole. Also required for ciliary basal feet formation and microtubule anchoring to mother centriole.
See full target information KIF3A

Publications (48)

Recent publications for all applications. Explore the full list and refine your search

Cell death and differentiation 32:1930-1945 PubMed40275081

2025

Alternative spliceosomal protein Eftud2 mediated Kif3a exon skipping promotes SHH-subgroup medulloblastoma progression.

Applications

Unspecified application

Species

Unspecified reactive species

Ying Li,Liping Chen,Saisai Xue,Zhihong Song,Heli Liu,Hao Li,Wei Shen,Chen Zhang,Haitao Wu

Life science alliance 7: PubMed39293864

2024

Ccrk-Mak/Ick signaling is a ciliary transport regulator essential for retinal photoreceptor survival.

Applications

Unspecified application

Species

Unspecified reactive species

Taro Chaya,Yamato Maeda,Ryotaro Tsutsumi,Makoto Ando,Yujie Ma,Naoko Kajimura,Teruyuki Tanaka,Takahisa Furukawa

Journal of the American Society of Nephrology : JASN 33:1726-1741 PubMed35961787

2022

KLC3 Regulates Ciliary Trafficking and Cyst Progression in CILK1 Deficiency-Related Polycystic Kidney Disease.

Applications

Unspecified application

Species

Unspecified reactive species

Gyuyeong Rah,Hwayeon Cha,Joohee Kim,Jieun Song,Hyunho Kim,Yun Kyu Oh,Curie Ahn,Minyong Kang,Jongmin Kim,Kyung Hyun Yoo,Min Jung Kim,Hyuk Wan Ko,Je Yeong Ko,Jong Hoon Park

Cell death & disease 13:599 PubMed35821021

2022

Tumor suppressive role of microRNA-139-5p in bone marrow mesenchymal stem cells-derived extracellular vesicles in bladder cancer through regulation of the KIF3A/p21 axis.

Applications

Unspecified application

Species

Unspecified reactive species

Ying Xiang,Dong Lv,Tao Song,Chao Niu,Ying Wang

Nature biomedical engineering 6:463-475 PubMed35478224

2022

Modelling ciliopathy phenotypes in human tissues derived from pluripotent stem cells with genetically ablated cilia.

Applications

Unspecified application

Species

Unspecified reactive species

Nelly M Cruz,Raghava Reddy,José L McFaline-Figueroa,Christine Tran,Hongxia Fu,Benjamin S Freedman

Matrix biology : journal of the International Society for Matrix Biology 107:1-23 PubMed35122963

2022

Coordination of two kinesin superfamily motor proteins, KIF3A and KIF13A, is essential for pericellular matrix degradation by membrane-type 1 matrix metalloproteinase (MT1-MMP) in cancer cells.

Applications

Unspecified application

Species

Unspecified reactive species

Valentina Gifford,Anna Woskowicz,Noriko Ito,Stefan Balint,B Christopher Lagerholm,Michael L Dustin,Yoshifumi Itoh

International journal of molecular sciences 22: PubMed34360830

2021

Photoreceptor Compartment-Specific TULP1 Interactomes.

Applications

Unspecified application

Species

Unspecified reactive species

Lindsey A Ebke,Satyabrata Sinha,Gayle J T Pauer,Stephanie A Hagstrom

Cell reports 36:109369 PubMed34260917

2021

Molecular motor protein KIF5C mediates structural plasticity and long-term memory by constraining local translation.

Applications

Unspecified application

Species

Unspecified reactive species

Supriya Swarnkar,Yosef Avchalumov,Isabel Espadas,Eddie Grinman,Xin-An Liu,Bindu L Raveendra,Aya Zucca,Sonia Mediouni,Abhishek Sadhu,Susana Valente,Damon Page,Kyle Miller,Sathyanarayanan V Puthanveettil

The Journal of cell biology 220: PubMed33439240

2021

Small noncoding vault RNA modulates synapse formation by amplifying MAPK signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Shuji Wakatsuki,Yoko Takahashi,Megumi Shibata,Naoki Adachi,Tadahiro Numakawa,Hiroshi Kunugi,Toshiyuki Araki

Glia 69:1184-1203 PubMed33368703

2020

Kif3a deletion prevents primary cilia assembly on oligodendrocyte progenitor cells, reduces oligodendrogenesis and impairs fine motor function.

Applications

Unspecified application

Species

Unspecified reactive species

Carlie L Cullen,Megan O'Rourke,Shannon J Beasley,Loic Auderset,Yilan Zhen,Renee E Pepper,Robert Gasperini,Kaylene M Young
View all publications

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com