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AB62104

Anti-KIF5A + KIF5B + KIF5C antibody

5

(4 Reviews)

|

(6 Publications)

Rabbit Polyclonal KIF5A antibody. Suitable for IP, WB, IHC-P, ICC/IF, IHC-Fr and reacts with Mouse, Rat, Human samples. Cited in 6 publications. Immunogen corresponding to Synthetic Peptide within Human KIF5A.

View Alternative Names

NKHC1, KIF5A, Kinesin heavy chain isoform 5A, Kinesin heavy chain neuron-specific 1, Neuronal kinesin heavy chain, NKHC, KNS, KNS1, KIF5B, Kinesin-1 heavy chain, Conventional kinesin heavy chain, Ubiquitous kinesin heavy chain, UKHC, KIAA0531, NKHC2, KIF5C, Kinesin heavy chain isoform 5C, Kinesin heavy chain neuron-specific 2, Kinesin-1

3 Images
Immunocytochemistry/ Immunofluorescence - Anti-KIF5A + KIF5B + KIF5C antibody (AB62104)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-KIF5A + KIF5B + KIF5C antibody (AB62104)

Immunofluorescence of KIF5 in K562 cells using ab62104 at 20 ug/ml.

Immunocytochemistry/ Immunofluorescence - Anti-KIF5A + KIF5B + KIF5C antibody (AB62104)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-KIF5A + KIF5B + KIF5C antibody (AB62104)

ab62104 at 5 μg/ml staining KIF5A + KIF5B + KIF5C in human K562 cells by Immunocytochemistry.

Western blot - Anti-KIF5A + KIF5B + KIF5C antibody (AB62104)
  • WB

Unknown

Western blot - Anti-KIF5A + KIF5B + KIF5C antibody (AB62104)

Lane 1:

Western blot - Anti-KIF5A + KIF5B + KIF5C antibody (ab62104) at 0.5 µg/mL

Lane 2:

Western blot - Anti-KIF5A + KIF5B + KIF5C antibody (ab62104) at 1 µg/mL

All lanes:

K562 cell lysate

Predicted band size: 110 kDa

Observed band size: 116 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human, Rat, Mouse

Applications

IP, ICC/IF, WB, IHC-Fr, IHC-P

applications

Immunogen

Synthetic Peptide within Human KIF5A. The exact immunogen used to generate this antibody is proprietary information.

Q12840

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "IHCFr" : {"fullname" : "Immunohistochemistry (Frozen sections)", "shortname":"IHC-Fr"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p>See Abreview.</p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-1 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/500", "ICCIF-species-notes": "<p></p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" }, "Mouse": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p>See Abreview.</p>", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" }, "Rat": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p>See Abreview.</p>", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL). Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. The ZFYVE27-KIF5A complex contributes to the vesicular transport of VAPA, VAPB, SURF4, RAB11A, RAB11B and RTN3 proteins in neurons. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation.
See full target information KIF5A

Additional targets

KIF5B,KIF5C
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Publications (6)

Recent publications for all applications. Explore the full list and refine your search

The Journal of cell biology 220: PubMed33439240

2021

Small noncoding vault RNA modulates synapse formation by amplifying MAPK signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Shuji Wakatsuki,Yoko Takahashi,Megumi Shibata,Naoki Adachi,Tadahiro Numakawa,Hiroshi Kunugi,Toshiyuki Araki

eLife 8: PubMed30747709

2019

Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis.

Applications

Unspecified application

Species

Unspecified reactive species

Shuo-Chien Ling,Somasish Ghosh Dastidar,Seiya Tokunaga,Wan Yun Ho,Kenneth Lim,Hristelina Ilieva,Philippe A Parone,Sheue-Houy Tyan,Tsemay M Tse,Jer-Cherng Chang,Oleksandr Platoshyn,Ngoc B Bui,Anh Bui,Anne Vetto,Shuying Sun,Melissa McAlonis-Downes,Joo Seok Han,Debbie Swing,Katannya Kapeli,Gene W Yeo,Lino Tessarollo,Martin Marsala,Christopher E Shaw,Greg Tucker-Kellogg,Albert R La Spada,Clotilde Lagier-Tourenne,Sandrine Da Cruz,Don W Cleveland

Nature communications 8:1505 PubMed29138405

2017

Ca signals initiate at immobile IP receptors adjacent to ER-plasma membrane junctions.

Applications

Unspecified application

Species

Unspecified reactive species

Nagendra Babu Thillaiappan,Alap P Chavda,Stephen C Tovey,David L Prole,Colin W Taylor

Proceedings of the National Academy of Sciences of 114:E2955-E2964 PubMed28320970

2017

BORC/kinesin-1 ensemble drives polarized transport of lysosomes into the axon.

Applications

Unspecified application

Species

Unspecified reactive species

Ginny G Farías,Carlos M Guardia,Raffaella De Pace,Dylan J Britt,Juan S Bonifacino

The Journal of neuroscience : the official journal of the Society for Neuroscience 36:9647-58 PubMed27629715

2016

Soluble Conformers of Aβ and Tau Alter Selective Proteins Governing Axonal Transport.

Applications

Unspecified application

Species

Unspecified reactive species

Mathew A Sherman,Michael LaCroix,Fatou Amar,Megan E Larson,Colleen Forster,Adriano Aguzzi,David A Bennett,Martin Ramsden,Sylvain E Lesné

The Journal of biological chemistry 289:1213-26 PubMed24302729

2013

Brain-derived neurotrophic factor (BDNF)-induced mitochondrial motility arrest and presynaptic docking contribute to BDNF-enhanced synaptic transmission.

Applications

Unspecified application

Species

Rat

Bo Su,Yun-Song Ji,Xu-lu Sun,Xiang-Hua Liu,Zhe-Yu Chen
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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