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AB25715

Anti-KIF5B antibody

4

(2 Reviews)

|

(6 Publications)

Rabbit Polyclonal KIF5B antibody. Suitable for WB and reacts with Pig, Human samples. Cited in 6 publications. Immunogen corresponding to Recombinant Fragment Protein within Human KIF5B.

View Alternative Names

KNS, KNS1, KIF5B, Kinesin-1 heavy chain, Conventional kinesin heavy chain, Ubiquitous kinesin heavy chain, UKHC

1 Images
Western blot - Anti-KIF5B antibody (AB25715)
  • WB

Unknown

Western blot - Anti-KIF5B antibody (AB25715)

All lanes:

Western blot - Anti-KIF5B antibody (ab25715)

Lane 1:

Human HEK cell line

Lane 2:

Porcine brain

Predicted band size: 110 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human, Pig

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human KIF5B. The exact immunogen used to generate this antibody is proprietary information.

P33176

Specificity

This antibody detects total level of endogenous kinesin protein.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>" }, "Pig": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Purification notes
Purified from rabbit serum by afinity chromatography. > 95% pure (by SDS PAGE).
Storage buffer
pH: 7.4 Preservative: 0.097% Sodium azide
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner (By similarity). Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes (PubMed : 20386726). Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation (By similarity). Through binding with PLEKHM2 and ARL8B, directs lysosome movement toward microtubule plus ends (Probable). Involved in NK cell-mediated cytotoxicity. Drives the polarization of cytolytic granules and microtubule-organizing centers (MTOCs) toward the immune synapse between effector NK lymphocytes and target cells (PubMed : 24088571).
See full target information KIF5B
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Publications (6)

Recent publications for all applications. Explore the full list and refine your search

Current biology : CB 34:4476-4494.e11 PubMed39276769

2024

Systems mapping of bidirectional endosomal transport through the crowded cell.

Applications

Unspecified application

Species

Unspecified reactive species

Marlieke L M Jongsma,Nina Bakker,Lenard M Voortman,Roman I Koning,Erik Bos,Jimmy J L L Akkermans,Lennert Janssen,Jacques Neefjes

Histology and histopathology 38:1009-1016 PubMed36861878

2023

Treatment of berberine alleviates diabetic nephropathy by reducing iron overload and inhibiting oxidative stress.

Applications

Unspecified application

Species

Unspecified reactive species

Yujing Wang,Shuling Yue,Feng Cai,Wen Zhu,Yuxiang Zhong,Juanjuan Chen,Chunyun Li

Cell reports 30:269-283.e6 PubMed31914393

2020

TACC3 Regulates Microtubule Plus-End Dynamics and Cargo Transport in Interphase Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Colleen Furey,Vladimir Jovasevic,Derek Walsh

Cell reports 20:2792-2799 PubMed28930676

2017

Localized Phosphorylation of a Kinesin-1 Adaptor by a Capsid-Associated Kinase Regulates HIV-1 Motility and Uncoating.

Applications

Unspecified application

Species

Unspecified reactive species

Viacheslav Malikov,Mojgan H Naghavi

Nature communications 6:6660 PubMed25818806

2015

HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus.

Applications

ICC/IF, WB

Species

Unspecified reactive species, Unspecified reactive species

Viacheslav Malikov,Eveline Santos da Silva,Vladimir Jovasevic,Geoffrey Bennett,Daniel A de Souza Aranha Vieira,Bianca Schulte,Felipe Diaz-Griffero,Derek Walsh,Mojgan H Naghavi

Brain : a journal of neurology 135:2058-73 PubMed22719003

2012

Alterations in axonal transport motor proteins in sporadic and experimental Parkinson's disease.

Applications

ICC/IF

Species

Rat

Yaping Chu,Gerardo A Morfini,Lori B Langhamer,Yinzhen He,Scott T Brady,Jeffrey H Kordower
View all publications
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