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AB95884

Anti-KIF7 antibody

4

(1 Review)

|

(2 Publications)

Rabbit Polyclonal KIF7 antibody. Suitable for WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human KIF7 aa 1200-1300.

View Alternative Names

UNQ340/PRO539, KIF7, Kinesin-like protein KIF7

1 Images
Western blot - Anti-KIF7 antibody (AB95884)
  • WB

Unknown

Western blot - Anti-KIF7 antibody (AB95884)

All lanes:

Western blot - Anti-KIF7 antibody (ab95884) at 0.4 µg/mL

Lane 1:

HeLa whole cell lysate at 50 µg

Lane 2:

HeLa whole cell lysate at 15 µg

Lane 3:

HeLa whole cell lysate at 5 µg

Lane 4:

293T whole cell lysate at 50 µg

Predicted band size: 150 kDa

true

Exposure time: 30s

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Synthetic Peptide within Human KIF7 aa 1200-1300. The exact immunogen used to generate this antibody is proprietary information.

Q2M1P5

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000 - 1/10000", "WB-species-notes": "<p></p>" }, "Gorilla": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Orangutan": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rhesus monkey": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Product details

Shelf Life: 1 year from date of receipt
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 - 8 Preservative: 0.09% Sodium azide Constituents: Tris citrate/phosphate
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
The product can be stored for up to 12 months
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Essential for hedgehog signaling regulation : acts both as a negative and positive regulator of sonic hedgehog (Shh) and Indian hedgehog (Ihh) pathways, acting downstream of SMO, through both SUFU-dependent and -independent mechanisms (PubMed : 21633164). Involved in the regulation of microtubular dynamics. Required for proper organization of the ciliary tip and control of ciliary localization of SUFU-GLI2 complexes (By similarity). Required for localization of GLI3 to cilia in response to Shh. Negatively regulates Shh signaling by preventing inappropriate activation of the transcriptional activator GLI2 in the absence of ligand. Positively regulates Shh signaling by preventing the processing of the transcription factor GLI3 into its repressor form. In keratinocytes, promotes the dissociation of SUFU-GLI2 complexes, GLI2 nuclear translocation and Shh signaling activation (By similarity). Involved in the regulation of epidermal differentiation and chondrocyte development (By similarity).
See full target information KIF7
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Human molecular genetics 28:764-777 PubMed30388222

2018

The deubiquitinating enzyme Usp14 controls ciliogenesis and Hedgehog signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Filomena Massa,Roberta Tammaro,Miguel A Prado,Marcella Cesana,Byung-Hoon Lee,Daniel Finley,Brunella Franco,Manuela Morleo

PloS one 9:e108248 PubMed25265279

2014

Downregulation of the gli transcription factors regulator Kif7 facilitates cell survival and migration of choriocarcinoma cells.

Applications

WB

Species

Human

Joanna Ho,Yanan Du,Oscar Gee-Wan Wong,Michelle K Y Siu,Karen K L Chan,Annie N Y Cheung
View all publications
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