JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB231002

Anti-Kinectin 1 antibody

Be the first to review this product! Submit a review

|

(1 Publication)

Rabbit Polyclonal Kinectin 1 antibody. Suitable for WB, IHC-P and reacts with Rat, Human samples. Cited in 1 publication.

View Alternative Names

Ktn1

4 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Kinectin 1 antibody (AB231002)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Kinectin 1 antibody (AB231002)

Formalin-fixed, paraffin-embedded rat testis tissue stained for kinectin 1 using ab231002 at 20 μg/ml in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Kinectin 1 antibody (AB231002)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Kinectin 1 antibody (AB231002)

Formalin-fixed, paraffin-embedded rat stomach tissue stained for Kinectin 1 using ab231002 at 20 μg/ml in immunohistochemical analysis.

Western blot - Anti-Kinectin 1 antibody (AB231002)
  • WB

Supplier Data

Western blot - Anti-Kinectin 1 antibody (AB231002)

All lanes:

Western blot - Anti-Kinectin 1 antibody (ab231002) at 1/250 dilution

All lanes:

HeLa (human epithelial cell line from cervix adenocarcinoma) cell lysate

Predicted band size: 109 kDa,156 kDa,214 kDa

false

Western blot - Anti-Kinectin 1 antibody (AB231002)
  • WB

Supplier Data

Western blot - Anti-Kinectin 1 antibody (AB231002)

All lanes:

Western blot - Anti-Kinectin 1 antibody (ab231002) at 1/250 dilution

All lanes:

Recombinant rat Kinectin 1 protein

Predicted band size: 123 kDa,156 kDa,17 kDa,20 kDa,21 kDa,23 kDa,28 kDa,312 kDa,49 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Rat, Human

Applications

WB, IHC-P

applications

style
left-column

Alternative Products

Primary Antibodies

AB224324

Anti-Kinectin 1 antibody

Immunocytochemistry/ Immunofluorescence - Anti-Kinectin 1 antibody (AB224324)

  • 0
  • 0

Complementary Products

Primary Antibodies

AB227506

Anti-UFL1 antibody - N-terminal

Western blot - Anti-UFL1 antibody - N-terminal (AB227506)

  • 0
  • 0
Primary Antibodies

AB236393

Anti-Kv beta 1/KCNAB1 antibody [OTI9F7]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Kv beta 1/KCNAB1 antibody [OTI9F7] (AB236393)

  • 0
  • 0
Primary Antibodies

AB231061

Anti-CD55 antibody

Western blot - Anti-CD55 antibody (AB231061)

  • 0
  • 0
Primary Antibodies

AB150385

Anti-LAMB3 antibody [EPR7525]

RabMAb|Recombinant

Western blot - Anti-LAMB3 antibody [EPR7525] (AB150385)

  • 0
  • 0
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.2-2 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.2-2 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5-20 µg/mL", "IHCP-species-notes": "<p></p>" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Purification notes
ab231002 was purified by antigen-specific affinity chromatography followed by Protein A affinity chromatography.
Storage buffer
pH: 7.4 Preservative: 0.011% Proclin 300 Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Kinectin 1 also known as kinectin is a protein with a molecular mass of approximately 156 kDa. Predominantly located in the endoplasmic reticulum kinectin 1 functions as a membrane anchor for kinesin motors. This protein facilitates the movement of organelles along microtubules by binding to kinesin which is essential for intracellular transport. Kinectin 1 expression can be detected in various tissues but is notably high in the brain liver and kidney reflecting its involvement in critical cellular processes.
Biological function summary

Kinectin 1 plays an important role in the organization of the cytoskeleton. It interacts with other cytoskeletal components and participates in the assembly of the Golgi apparatus. Kinectin 1 also forms part of the larger motor protein complex that includes kinesin light chains and other adaptors critical for vesicle-mediated transport. This complex is responsible for maintaining cellular homeostasis and efficient distribution of materials within the cell.

Pathways

Kinectin 1 is integral to the intracellular trafficking and signaling pathways. It is closely associated with the secretory and endocytic pathways both of which depend on accurate and timely transport of proteins and membranes. Kinectin 1 collaborates with proteins like kinesin and cytoplasmic dynein facilitating directional transport along microtubules. This interaction is vital for the proper functioning of cellular logistics and signaling cascades.

Research shows that kinectin 1 is connected to neurodegenerative diseases such as Alzheimer's. Disruption in its normal function or expression can lead to impaired intracellular transport contributing to the pathogenesis of such conditions. Additionally kinectin 1 interacts with kinesin motor proteins in processes that when dysregulated may relate to metabolic disorders impacting cellular energy distribution. Understanding these connections could inform therapeutic strategies for related diseases.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

See full target information Kinectin 1
style
left-column

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in molecular neuroscience 14:688050 PubMed34630032

2021

Tandem Mass Tag-Based Quantitative Proteomic Analysis Reveals Pathways Involved in Brain Injury Induced by Chest Exposure to Shock Waves.

Applications

Unspecified application

Species

Unspecified reactive species

Changci Tong,Peifang Cong,Ying Liu,Xiuyun Shi,Lin Shi,Shun Mao,Yan Zhao,Mingxiao Hou,Yunen Liu
View all publications
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com