Anti-Klebsiella pneumoniae antibody
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(4 Publications)
Reactivity data
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Supplementary information
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Biological function summary
Klebsiella pneumoniae plays a significant role in infections. The organism is noted for its pathogenic mechanisms which include evading host immune responses and harboring antibiotic resistance genes. It produces a robust polysaccharide capsule an important virulence factor and a siderophore production system for iron acquisition aiding in infection and persistence in host tissues. The bacterium does not form interlinked complexes with other microorganisms but it interacts with host cells and immune system components influencing the immune response.
Pathways
Klebsiella pneumoniae impacts metabolic routes related to its persistence and virulence. Iron uptake pathways important for its survival and growth involve proteins such as enterobactin which are essential for iron binding and transport. The bacterium also engages in nitrogen metabolism pathways that facilitate its growth in nutrient-limiting environments. Its ability to manipulate these pathways allows it to thrive in diverse environments including host tissues.
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Publications (4)
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Chemical science 11:3054-3067 PubMed34122810
2020
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The Journal of veterinary medical science 79:1167-1171 PubMed28529273
2017
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PloS one 9:e110703 PubMed25333280
2014
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Mikrochimica acta 181:1707-1714 PubMed25253911
2014
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