Rabbit Polyclonal L3MBTL4 antibody. Suitable for WB, IHC-P and reacts with Rat, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human L3MBTL4 aa 1-300.
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Lethal(3)malignant brain tumor-like protein 4, H-l(3)mbt-like protein 4, L(3)mbt-like protein 4, L3mbt-like 4, L3MBTL4
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-L3MBTL4 antibody (AB235089)
Paraffin-embedded human testis tissue stained for L3MBTL4 using ab235089 at 1/100 dilution in immunohistochemical analysis.
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-L3MBTL4 antibody (AB235089)
Paraffin-embedded human prostate cancer tissue stained for L3MBTL4 using ab235089 at 1/100 dilution in immunohistochemical analysis.
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Supplementary information
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Biological function summary
L3MBTL4 influences chromatin state and gene expression by interacting with other chromatin-associated proteins participating in the silencing of genes. This protein is a part of larger complexes involved in chromatin modification notably influencing transcriptional repression activities. It contributes to the regulation of various genes thereby impacting cell cycle progression and differentiation events within cells.
Pathways
L3MBTL4 participates in the regulation of key processes such as the cell cycle and epigenetic modification pathways. It interacts with proteins like RB and members of the PcG complex to modulate these pathways ensuring appropriate cell proliferation and differentiation. L3MBTL4 also plays a role in histone modification pathways further highlighting its importance in gene expression regulation through its interaction with other chromatin modulators.
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Publications (1)
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Nature communications 14:3729 PubMed37349316
2023
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